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5 Cards in this Set
- Front
- Back
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Name TH2 Cytokines and their actions
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IL-2 (also from TH1) -- Stimulates Tcell growth
IL-4 -- Bcell differentiation (switch to IgE) IL-5 -- Bcell differentiation (switch to IgA) IL-6 (also TH1&Macrophage) --Stimulates production of acute phase reactants and is a pyogen IL-10 -- Stimulates TH2 and Inhibits TH1 (cellular immunity) |
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Name TH1 Cytokines and their actions
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IL-2 (also from TH2) -- Stimulates Tcell growth
IL-6 (also TH2&Macrophage) --Stimulates production of acute phase reactants and is a pyogen IFN-gamma -- Stimulates TH1, inhibits TH2 |
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Name Macrophages' cytokines and their actions
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IL-1 --Endogenous pyogen
IL-6 (also TH1&2) --Stimulates production of acute phase reactants and is a pyogen IL-8 -- Major chemotactic factor for neutrophils TNF-alpha --Leukocyte recruitment and vascular leakage (key in septic shock) |
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Name Bcells' cytokines and their actions
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IL-12 (also by macrophages) --Activates Th1 and NK cells
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Pneumonic for cytokines 1-5?
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HOT T-Bone stEAk
IL-1 = fever (hot) IL-2 = Tcell activator IL-3 = Bone marrow stimulation (similar to GM-CSF) IL-4 = activates switch to IgE IL-5 = activates switch to IgA |
