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12 Cards in this Set
- Front
- Back
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What are the 10 essential amino acids?
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"Any Help In Learning these Little Molecules Proves Truly Valuable."
Arginine (urea cycle) Histidine Isoleucine Leucine (ketogenic) Threonine Lycine (ketogenic) Methionine Phenylalanine Tryptophan Valine |
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What are the substances used in the urea cycle?
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" ordinarily, careless crappers are also frivolous about urination"
ornithine carbamoyl phosphate citrulline aspartate argininosuccinate fumarate arginine urea |
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What are the substances used in the TCA cycle?
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" cindy is kinky so she fornicates more often"
citrate isocitrate ketoglutarate (alpha-) succinyl coa succinate fumarate malate oxaloacetate |
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What are the familial dyslipidemias?
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1=chylo (lipop.lipase/apoCII)
2=LDL (a=receptor, b=production) 3=IDL (apoE) 4=VLDL (prod) 5=VLDL and chylo (prod/clear) |
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What crystals are found in gout?
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monosodium urate (not uric acid!)
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What is different between endo and exopeptidases?
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endo: cleave aminobond within protein
exo: cleav ends of -> aminopeptidase or carboxypeptidase nb amino acid sequences are given in N-C order |
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Where are glut1-5 found?
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1= RBC, brain vessels, kidney, colon
2= liver, pancreas 3= neurons, placenta, testes 4= muscle (only one influenced by insulin) 5= sm intestine, testes, sperm (=fructose transporter) |
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What are serine proteases?
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cleave proteins and have serine residue
trypsin, chymotrypsin, thrombin, plasminogen, plasmin, elastase, cathepsin G |
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What does albumin consist of en what is essential in the making?
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glycoprotein
protein, carbohydrate chains synthesized on dolichol |
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What is Hartnups disease
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epithelial transport neutral AA -> sx vlg pellagra
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What are basics of purines and pyrimidines
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purine: aspartate, co2, glycine, n10-formyl-tetrahydrofolate, glutamine
pyrimidine: carbamoyl phosphate, aspartate (source of cleaved co2) |
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Which type of disease in newborns presents with:
a) severe hyperammonemia and respiratory alkalosis b) hypoketotic hypoglycemia, hyperammonemia and cardiomyopathy c) hypoglycemia, lactic/ketoacidosis and hepatosplenomegaly d) feeding difficulties, lethargy, seizures, coma, renal/liver disease e) metabolic acidosis with ketosis, elevated lactate, mild hyperammonemia, vomiting, encephalopathy, neutropenia, thrombocytopenia |
a) urea cycle defects
b) # fatty acid oxidation c) # carbohydrate metabolism d) aminoacidopathy e) organic acidemias |
