Usmle 9 Bateman

Front 1

hemophilia B inheritance

Back 1

x-linked

Front 2

lesch-nyhan dz inheritance

Back 2

x-linked

Front 3

classical galactosemia inheritance

Back 3

AR

Front 4

primary outcome of a case-control study

Back 4

exposure odds ratio

can't generate indcidence measures (e.g.- RR) because the people already have the dz

Front 5

power formula

Back 5

power = 1- beta

beta = type II error = stating there is no difference when there is a difference

Front 6

Langerhans giant cells in TB

Back 6

macrophages that were activated by CD4+ TH1 cells

Front 7

net filtration pressure

Back 7

NFP = (Pc - Pi) - (ONCOTIC c - ONCOTIC i)

c = capillary
i = interstitium

Front 8

what pH do uric acid and cysteine stones form at?

Back 8

low (acidic) pH

Front 9

what pH do Ca2+ salt stones form at?

Back 9

acidic or neutral pH

Front 10

what pH do struvite stones form at?

Back 10

alkaline pH

Front 11

Reid index

Back 11

mucous layer thickness / bronchial wall between respiratory epithelium and bronchial cartilage

increased = chronic bronchitis

Front 12

what would cause ANP/BNP to be formed in ventricular myocytes

Back 12

ventricular hypertrophy and volume overload

Front 13

Reserpine

Back 13

cheap and old antiHTN drug

blocks adrenergic mediators in pre-synaptic vesicles

predisposes to depression, nasal congestion, and increases gastric acid that leads to peptic ulcers

Front 14

Lesch-Nyhan: what enzyme would be INCREASED?

Back 14

def in HGPRT

so PRPP synthase has to increase

Front 15

which clinical illness is worse: acute HCV or HBV?

Back 15

HCV is usually mild

HBV is associated with serum-sickness like syndrome in the prodromal period

Front 16

drug half-life formula

Back 16

T 1/2 = (Vd x ln2)/CL

Front 17

major serious side effect from buproprion

Back 17

seizures

Front 18

drugs that lead to seizures

Back 18

buproprion
isoniazid (if not given with B6)
imipenem

Front 19

bioavailability (F) formula

Back 19

F = (AUC oral x dose IV)/(AUC IV x dose oral)

Front 20

volume of distribution formula

Back 20

Vd = amt of drug in body / plasma concentration of drug

Front 21

genetic defect of carbonic anhydrase II

Back 21

osteopetrosis

Front 22

Anti-Jo-I antibody

Back 22

polymyositis, dermatomyositis

Front 23

anti-desmosome antibodies

Back 23

pemphigus vulgaris

Front 24

anti-hemidesmosome antibodies

Back 24

bullous pemphigoid

Front 25

P450 inducers

Back 25

Queen Barb Steals Phen-phen and Refuses Greasy Carbs Chronically

Quinidine
Barbituates
St. jons wort
Phenytoin
Rifampin
Griseofulvin
Carbamazepine
Chronic EtoH use

Front 26

P450 inhibitors

Back 26

SICK AGE

Sulfa drugs
Isoniazid
Cimetidine
Ketoconazole

Acute EtOH
Grapefruit juice
Erythromycin

Front 27

Meissner's corpuscles

Back 27

position sense, dynamic fine touch, adapt quickly

glabrous (hairless) skin

Front 28

Pacinian corpuscles

Back 28

vibration, pressure

deep skin layers, ligaments, and joints

Front 29

Merkel's disks

Back 29

Position sense, static touch, adapt slowly

hair follicles

Front 30

supraoptic nucleus

Back 30

makes ADH

Front 31

paraventricular nucleus

Back 31

makes oxytocin

Front 32

lateral hypothalamus

Back 32

hunger

destruction --> anorexia

Front 33

ventromedial hypothalamus

Back 33

satiety

destruction --> hyperphagia

Front 34

anterior hypothalamus

Back 34

cooling, parasympathetic

anterior = A/C

Front 35

posterior hypothalamus

Back 35

heating, sympathetic

destruction --> poikilotherm (cold-blooded, cant regular body heat)

Front 36

septal nucleus

Back 36

sexual urges

Front 37

suprachiasmatic nucleus

Back 37

circadian rhythm

Front 38

PICA stroke

Back 38

lateral medullary syndrome (Wallenberg's syndrome)

Front 39

AICA stroke

Back 39

lateral pontine syndrome

Front 40

biconcave disc on CT

Back 40

epidural hematoma

Front 41

brain bleed that does not cross suture lines

Back 41

epidural hematoma

Front 42

crescent shaped brain bleed

Back 42

subdural hematoma

Front 43

brain bleed that crosses suture lines

Back 43

subdural

Front 44

red nuron after ischemic brain disease (time)

Back 44

12-48 hours

Front 45

foramen of monroe

Back 45

lateral --> 3rd ventricle

Front 46

foramen of Luschka

Back 46

lateral drainage from 4th --> SA space

Front 47

foramen of Magendie

Back 47

medial drainage from 4th --> SA space

Front 48

NPH pathophysiology

Back 48

expansion --> distortion of corona radiata fibers --> dementia, ataxia, urinary incontinence

Front 49

Werndig-Hoffman dz

Back 49

infantile spinal-muscular atrophy

AR inheritance

presents as floppy baby with tongue fasiculations

die in 1st year

Front 50

Friedreich's ataxia

Back 50

AR inherited trinucleotide expansion d/o

impairment in mito function

staggering gait, frequent falling, nystagmus, dysarthria, pes cavus, hammer toes

Front 51

usual COD in children with Freidrich's ataxia

Back 51

hypertrophic cardiomyopathy

Front 52

Parinaud syndrome

Back 52

paralysis of conjugate vertical gaze due to lesion in superior colliculus

Front 53

Nucleus Solitarius

Back 53

visceral sensory info (tase, baroreceptors, gut distention)

CN VII, IX, X

Front 54

Cavernous sinus syndrome

Back 54

ophthalmoplegia, ophthalmic and maxillary sensory loss

Front 55

muscles that open the jaw

Back 55

massiter, temporalis, medial pterygoid

Front 56

muscles that close jaw

Back 56

lateral pterygoid

Front 57

muscles with "glossus" innervation

exceptions?

Back 57

glossus = CN XII except palatoglossus (CN X)

Front 58

muscles with "palat" innervation

exceptions?

Back 58

palat = CN X except tenser veli palatini (CN V3)