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64 Cards in this Set
- Front
- Back
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gas anesthetics + succinylcholine
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malignant hyperthermia (uncontrolled ↑ in skel. m. oxidative metabolism)
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bupivicaine
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cardiotoxicity
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bromocriptine & pergolide (DA agonists)
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Raynaud's syndrome
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ziprasidone, TCAs
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prolong QT interval
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olanzapine, quetiapine
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metabolic syndrome
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PCN, methyldopa, quinidine
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AIHA
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clindamycin, ampicillin
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pseudomembranous colitis
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phenytoin
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gingival hyperplasia, hirsutism, megaloblastic anemia (blocks intestinal conjugate--> folate def), generalized lymphadenopathy (w/ atypical lymphocytes)
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psychotics (DA blockade)
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hyperprolactinemia--> ammenorrhea
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protease inhibitors (ritonavir, indinavir)
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lipodystrophy
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metclopromide
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parkinsonian effects (DA-antagonist)
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amlodipine
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lower extremidy edema
(L type Ca channel blocker) |
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bile acid binders
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inhibit absorbtion of many other drugs
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amiodarone vs. amiloride vs. amlodipine?
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amiodarone: Class III anti-arrhy.
amiloride: K sparing diuretic amlodipine: L-type Ca blocker |
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nitrates (nitroglycerin, isosorbide)
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HA, early tolerance
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statins, fibrates
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myositis
+ statins hepatitis |
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nitroprusside
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CN- toxicity
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diazoxide
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hyperglycema
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thiazides
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hyperGLUC
glycemia, lipidemia, uricemia, calcemia |
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verapamil
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constipation, AV block, gingival hyperplasia
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reserpine (for HTN)
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suicidal ideations & depression, nasal congestion, gastric ulcer
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hydralazine & minoxidil
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reflex tachy, salt retention (use w/ B-blockers & diuretic)
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agranulocytosis
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carbamazepine, clozapine, colchicine, thioamides (PTU, methimazole)
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aplastic anemia
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chloramphenicol, NSAIDs, thioamides
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mannitol
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pulmonary edema
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pulmonary fibrosis
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Amiodarone
Bleomycin & busulfan |
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cocaine, sumatriptin
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coronary vasopasm
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dilated cardiomyopathy
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doxorubicin, daunorubicin
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vincristine/vinblastine
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neurotoxicity (areflexia, peripheral neuritis)
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lithium (in utero)
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Ebstein's anomaly (displacement of tricuspid leaflets, RV volume, atrialization of R ventricle)
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mirtazapine, trazodone
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sedating anti-depressants
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drug induced lupus
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it's not HIPP to have SLE
Hydralazine INH Procainamide Phenytoin |
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ethambutol (for TB)
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optic neuritis
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buproprion, INH, imipenem
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seizures
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B6
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can increase peripheral metabolism of levodopa
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Syndrome of inappropriate ADH (SIADH)
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chlorpropamide (1st gen sulfonoylurea)
cyclophosphamide carbamazepine SSRIs |
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metformin
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lactic acidosis (pts w/ impaired renal fxn)
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cimetidine, ranitidine
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↓ renal excretion of creatinine
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methemoglobinemia
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trimethoprim, sulphonamides, dapsone, aniline dyes, nitrates
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allopurinol
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↑ toxicity of azathioprine, 6-MP (as these are metabolized by xanthine oxidase)
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gancyclovir
AZT/zidovudine toclipidine |
neutropenia
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amphoteracin B (anti-fungal)
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nephrotoxicity (hypoK, hypoMg) (reduce w/ hydration), IV phlebitis, fever/chills
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colcichine
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n/v, diarrhea (so not 1st line, NSAIDs ie indomethacin are)
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isoniazid
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age related hepatitis
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diabetes insipidus
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lithium
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tinnitus
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aspirin, quinidine
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hemolytic anemia in G6PD deficiency
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INH
Sulfonamides Primaquine dapsone |
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thyroid toxicity
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lithium
amiodarone |
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fetal spina bifida
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valproic acid
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methacillin
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intersticial nephritis
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acute cholestatic hepatitis
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macrolides
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photosensitivity
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sulfonamides
amiodarone tetracycilne |
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Fanconi's syndrome
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expired tetracycline
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ototoxicity & nephrotoxicity
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aminoglycosides
loop diuretics cisplatin |
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stevens johnson syndrome
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sulfonamides
ethosuximide |
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gynecomastia (5)
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Spironolactone, Digitalis, Cimetidine, Alcohol, Ketoconazole
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chloroquine
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retinal toxicity
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fulminant hepatitis (3)
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acetaminophen
halothane valproic acid |
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p450 inhibitors
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Inhibitors Stop Cyber-Kids from Eating Alot of Grapefruit Regularly
Isoniazid Sulfonamides Cimetidine, Cipro Ketoconazole Erythromycin Amiodarone Grapefruit Ritonavir |
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p450 inducers
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Queen Barb takes PhenPhen and Refuses Greasy Carb Shakes
Quinidine Barbs Phenytoin Rifampin Griseofulvin Carbamazepine St. John’s wort |
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thiazolidinones
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weight gain, edema (may exacerbate CHF)
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heparin
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skin necrosis (black) at injection site
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niacin
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gout
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fibric acid
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gallstones
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