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48 Cards in this Set

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MC arteries affected by Monckenberg arteriosclerosis
Radial and Ulnar arteries
Definition:

Hyaline thickening of small arteries in Essential HTN and DM
Arteriolosclerosis
Dx:

"Onionskin" thickening of the arteriolar walls
Hyperplastic Arteriolosclerosis

(Malignant HTN)
Definition:

Dx specific to an aneurysm of the Ascending Aorta

where does it exert its effect?
what heart problem can it lead to?
Syphillic (Leutic) Anneurysm

effects: Vaso Vasorum

leads to: Aortic valve incompetence
what may be confused w/ a MI if it wasn't for the normal serum enzymes?
Dissecting Aneurysm
Definition:

dilated small vessel surrounded by radiating fine channels and associated w/ hyperestrinism
Spider Telangiectasia
Dx:

Port-wine stain birthmark
Hemangioma
Dx:

Hemangioblastomas of the retina, cerebellum and medulla.
What can it lead to?

what genetics? gene?
Von Hippel-Lindau Dz

can lead to: Bilateral Renal Cell CA

genetics:
Auto Dominant;
deletion on VHL gene on chrom 3

(chrom 3 = 3 words in name VHL)
Malignant vascular tumor caused by Arsenic exposure
Hemangiosarcoma
Dx:

fever, weight loss, abd pain, HTN, cutaneous eruptions, arthralgia, vasculitis in arterioles and glomeruli of kidney

What is possible predisposing virus?
Polyarteritis Nodosa
(P-ANCA)


virus: HBV
Dx:

granulomatous vasculitis w/ eosinophilia and asthma; prominent in pulmonary vasculature
Churg-Strauss syndrome
Dx:

child w/ previous URI gets hemorrhagic urticaria of extensor surfaces, arthralgia, abd pain, melena
Henoch-Schonlein purpura
Dx:

necrotizing granulomatous vasculitis in lung and upper airway and necrotizing glomerulonephritis
Wegener's Glanulomatosis
(C-ANCA)
Dx:

unilateral HA, visual impairment, polymyalgia rheumatica (muscle pain), increased ESR
Temporal arteritis

(Giant cell arteritis)
Dx:

fever, arthritis, night sweats, myalgia, skin nodules, ocular disturbances, weak pulse in upper extremities, elevated ESR
Takayasu's Arteritis
Dx:

child w/ fever, congested conjuctiva, changes in lips/oral mucosa, lymphadenitis
Kawasaki Dz
Dx:

intermittent claudication, nodular phlebitis, cold sensitivity, heavy smoker
Buerger's Dz

(Tx: quit smoking)
Dx:

marked increase in diastolic BP, retinal hemorrhages, papilledema, "flea-bitten" kidney
Malignant HTN
Definition:

focal interstitial myocardial inflammation w/ fragmented collagen and fibrinoid material and some mulitnucleated giant cells; seen in Rheumatic fever
Aschoff Body

(w/ Anitschkow's cells)
MC coronary artery for MI
LAD
Definition:

Autoimmune phenomenon resulting in fibrinous pericarditis post-MI
Dressler's syndrome
what lab is elevated in Rheumatic Heart Dz?
elevated ASO titer
Dx:

fever, erythema marginatum, valvular damage, elevated ESR, polyarthritis, Sub-q nodules, chorea
Rheumatic Heart Dz

(mitral = MC valve)
MCC of Subacute Endocarditis
Strep Viridians
MCC of Acute Endocarditis
Staph Aureus
Definiton:

Endocarditis secondary to metastasis or renal failure
Marantic endocarditis

(can result in peripheral emboli)
(3) congenital Right -> Left shunts
3 Ts:

Tetralogy of Fallot;

Transposition of great vessels;

Truncus Arteriosus
Dx:

Fixed S2 split
ASD
Definition:

uncorrected VSD, ASD, or PDA leads to progressive pulmonary HTN. With Inc pulm resistance, shunt reverses from L -> R to
R -> L, causing late cyanosis, clubbing and polycythemia
Eisenmenger's syndrome
which congenital heart defect is not compatable with life unless a shunt is present?
Transposition of great vessels
Dx:

notching of ribs, HTN in upper extremities and weak pulses in lower extremities
Coarctation of Aorta
Dx:

continuous "machine-like" murmur
PDA
what is given to close a PDA?
Indomethacin
what is given to keep a PDA open?
Prostaglandins

[PROp it open]
Congenital defect with:

Congenital Rubella
(2)
Septal defect;

PDA
Congenital defect with:

Marfan's syndrome
Aortic insufficiency
Congenital defect with:

offspring of Diabetic mother
Transposition of Great vessels
Murmur:

systolic High-pitched "blowing"
Mitral Regurg
Murmur:

Midsystolic Click
Mitral Prolapse
Murmur:

Wide pulse-pressure
Aortic Regurg
MC heart tumor in children
Rhabdomyoma

(w/ Tuberous Sclerosis)
which type of emboli can lead to DIC?
Amniotic fluid embloi
Dx:

low CO, equilibrium of pressures in all 4 chambers, JVD, pulsus paradoxus
Cardiac tamponade
(4) causes of Serous Pericarditis
SLE;

RA;

Infection;

Uremia
(3)* causes of Fibrinous pericarditis
Fiber in your RUM:

Rheumatic fever;

Uremia;

MI
Fiber in your RUM
(4) signs of Tetralogy of Fallot
PROVe:

Pulmonary stenosis;

RVH;

Overriding Aorta;

VSD
developmental cause of Tetralogy of Fallot?
Anterosuperior displacement of Infundibular septum
Definition:

passage of emboli from the venous circulation into the arterial circulation via a R -> L shunt
Paradoxic Emboli