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45 Cards in this Set

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  • Back
b-mercaptoethanol
Reduces disulfide bonds.
2,4 dinitrophenol (DNP)
Uncouples ATP synthesis from ETC.
Acetaminophen
Hepatotoxic.
Aflatoxin
Hepatocellular CA.
Alcohol
FAS (Teratogen).
Aniline dye
Transitional cell CA of bladder.
Arsenic
(2)
- Angiosarcoma of Liver
- SCC
Asbestos
(2)
- Primary Lung CA
- Mesothelioma
Benzene
(3)
- Acute leukemia
- Aplastic anemia
- AML
Benzidine
Transitional cell CA of bladder.
Bungarotoxin (cobra venom)
Ach receptor blocker
Cadmium
(2)
- Prostate CA
- Lung CA
Carbon tetrachloride
Liver damage.
Carboxypeptidase
Carboxy terminus determination of protein structure.
Chewing tobacco
Verrucous CA of mouth.
Chloramphenicol
(2)
- Aplastic anemia
- Gray baby syndrome
Chromium
Lung CA.
Chymotrypsin
Cleaves protein at Phe, Tyr, Trp.
CNBr
Cleaves protein at Met.
Carbon Monoxide
(2)
- Inhibits complex IV of ETC blocking ATP synthesis
- Shifts OSC to Left
Cyanide
Inhibits complex IV of ETC blocking ATP synthesis.
Cyclophosphamide
Transitional cell CA of bladder.
Diethylstilbesterol
Clear cell adenocarcinoma. Teratogen.
Edmund's reagent
Amino terminus determination of protein structure.
Ethylene glycol; antifreeze
Oxalate crystals in renal tubules.
Iron excess
(2)
- Gastritis
- Hepatic necrosis
Lead
Microcytic anemia; blocks heme synthesis.
Lithium
Teratogen.
Methanol; windshield washer fluid
Blindness.
Nickel
Lung CA.
Ninhydrin
Detects amino acids (proline-yellow).
Nitrosamines
(2)
- Esophageal CA
- Gastric CA.
Oligomycin
Inhibitor of ATP synthesis from ETC.
Oral contraceptives
(3)
- Hepatocellular CA
- Liver cell adenoma
- blocks Folate absorption
Phenacetin
Transitional cell CA of bladder.
Rotenone
Inhibits complex I of ETC blocking ATP synthesis.
Salicylates
Respiratory alkalosis. Metabolic acidosis.
Smoke
SCC of lung, oral, esophagus. Transitional cell CA of bladder. Adenocarcinoma of pancreas.
Succinyl choline
Ach receptor perturbants.
Thalidomide
Teratogen.
Thorotrast
Angiosarcoma of Liver.
Trypsin
Cleaves protein at Arg, Lys.
Uranium
Lung CA.
Vinyl chloride
Angiosarcoma of Liver.
Warfarin
Teratogen.