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24 Cards in this Set

  • Front
  • Back
What percentage of children with urticaria will have angioedema?
What causes popular urticaria?
Ectoparasite hypersensitivity
What do heat and exercise urticaria look like?
10- to 20-mm red, blotchy macules with a 0.1-mm wheal in the center.
What is the primary chemical mediator of urticaria?
What is the primary chemical mediator of physical urticaria?
Neuropeptides in dermographism and heat and exercise urticaria; complement products in cold urticaria
What causes papular urticaria?
Basophil infiltrate around superficial dermal blood vessels
Infectious agents associated with transient urticaria
Infectious mononucleosis (Epstein-Barr virus)
Hepatitis A, B, and C
Medications associated with urticaria
Penicillin & Cephalosporins
Morphine, codeine, and other opiates
Nonsteroidal anti-inflammatory drugs
Blood and blood products
Foods associated with transient common urticaria
Nuts Eggs Shellfish Strawberries Tomatoes
Systemic disease associated with transient common urticaria
collagen vascular disease, inflammatory bowel disease, aphthous stomatitis, behcet disease or thyroiditis
How long does an episode of transient urticaria last?
24 hrs-3 weeks
What is angioedema?
Subcutaneous extension of urticarial lesion
Diagnosis of Hereditary angioedema?
serum C4 level is persistently low; confirmed by functional assay of the C1 esterase inhibitor
What does papular urticaria look like?
Has central puncti
Ddx of urticaria
Erythema multiforme Mastocytosis
Reactive erythemas
Juvenile rheumatoid arthritis Vasculitis
Guttate psoriasis
Pityriasis rosea (early lesions)
how is urticaria differentiated from mastocytosis?
Skin biopsy
how is urticaria differentiated from flushing?
Flushing is flat
how is urticaria differentiated from JRA?
Faint erythematous macules with clear centers are present and associated with spiking fever
how is urticaria differentiated from vasculitis lesions?
Vasculitis lesions have purpuric centers
how is urticaria differentiated from psoriasis?
Scale overlies the erythematous papules
how is urticaria differentiated from pityriasis rosea?
scaling overlies the erythematous papules
What is the Melkersson-Rosenthal syndrome?
a rare neurological disorder characterized by recurring facial paralysis, swelling of the face and lips (usually the upper lip), and the development of folds and furrows in the tongue
what diseases are associated with melkersson-rosenthal syndrome?
crohn syndrome and sarcoidosis
what can be added if angioedema is not controlled by antihistamines?