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24 Cards in this Set
- Front
- Back
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What percentage of children with urticaria will have angioedema?
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50%
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What causes popular urticaria?
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Ectoparasite hypersensitivity
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What do heat and exercise urticaria look like?
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10- to 20-mm red, blotchy macules with a 0.1-mm wheal in the center.
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What is the primary chemical mediator of urticaria?
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Histamine
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What is the primary chemical mediator of physical urticaria?
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Neuropeptides in dermographism and heat and exercise urticaria; complement products in cold urticaria
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What causes papular urticaria?
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Basophil infiltrate around superficial dermal blood vessels
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Infectious agents associated with transient urticaria
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Streptococcus
Infectious mononucleosis (Epstein-Barr virus) Hepatitis A, B, and C Adenovirus Enterovirus Parasites |
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Medications associated with urticaria
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Penicillin & Cephalosporins
Salicylates Morphine, codeine, and other opiates Nonsteroidal anti-inflammatory drugs Barbiturates Amphetamines Atropine Hydralazine Insulin Blood and blood products |
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Foods associated with transient common urticaria
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Nuts Eggs Shellfish Strawberries Tomatoes
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Systemic disease associated with transient common urticaria
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collagen vascular disease, inflammatory bowel disease, aphthous stomatitis, behcet disease or thyroiditis
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How long does an episode of transient urticaria last?
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24 hrs-3 weeks
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What is angioedema?
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Subcutaneous extension of urticarial lesion
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Diagnosis of Hereditary angioedema?
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serum C4 level is persistently low; confirmed by functional assay of the C1 esterase inhibitor
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What does papular urticaria look like?
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Has central puncti
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Ddx of urticaria
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Erythema multiforme Mastocytosis
Flushing Reactive erythemas Juvenile rheumatoid arthritis Vasculitis Guttate psoriasis Pityriasis rosea (early lesions) |
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how is urticaria differentiated from mastocytosis?
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Skin biopsy
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how is urticaria differentiated from flushing?
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Flushing is flat
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how is urticaria differentiated from JRA?
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Faint erythematous macules with clear centers are present and associated with spiking fever
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how is urticaria differentiated from vasculitis lesions?
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Vasculitis lesions have purpuric centers
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how is urticaria differentiated from psoriasis?
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Scale overlies the erythematous papules
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how is urticaria differentiated from pityriasis rosea?
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scaling overlies the erythematous papules
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What is the Melkersson-Rosenthal syndrome?
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a rare neurological disorder characterized by recurring facial paralysis, swelling of the face and lips (usually the upper lip), and the development of folds and furrows in the tongue
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what diseases are associated with melkersson-rosenthal syndrome?
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crohn syndrome and sarcoidosis
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what can be added if angioedema is not controlled by antihistamines?
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pseudoephedrine
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