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159 Cards in this Set

  • Front
  • Back
Urine leaving kidneys, travels along the following pathway to the exterior?
Ureter, Urinary Bladder, Urethra
Which organ does not belong to the urinary system?
a:Urethra b:Gall Bladder c:Urinary Bladder d: Kidneys
c: Ureters
B: Gall Bladder
The initial factor which determines if urine production occurs is
a: Secretion, b:Absorption
c: Sympathetic stimulation
d: Filtration
d: Filtration
Arrange in correct sequence from superior to deep?
a: Renal Capsule b:renal Medulla c:Renal Cortex, D: renal Pevis
Capsule,cortex,medulla, pelvis
Name the structures that form the renal corpuscle?
Bowman's capsule, Glomerulus
Describe the filtration membrane. Arrange in order the layers that fluid or solutes pass through as they move from blood into the forming urine:
Fenestrated capillary wall, B.M. of Lamina Densa,
Filtration Slits
what are the Filtration slits in the glomerulus?
Podocytes
Gromerular filtration is a process of pushing or Pulling? fluids and dilutes out of the glomerulus and into the fluid known as____?
pushing, Glomerular Filtrate
Name the waste product elliminated through urine?
urea, uric acid, NH4+
What does kidneys produce to regulate Blood Pressure?
Renin
Which product is vital to RBC production?
EPO (Erythropoietin
Which affects the Calcium absorption?
Calcitriol
What is the location of the kidneys?
Between T12 and L3 vertebrae
The ___ kidney is slightly superior to the___
Left and Right
The kidney are in the extreme anterior, or posterioir in the abdomen
Posterior
The kidneys are described as ___ since they are posterior to the peritoneum?
Retroperitoneal
The fnctional unit of the kidney
Nephron
microscope structures that are divided into two parts? in the nephron
renal corpuscle and renal tubule
Cuplike chamber of the renal corpuscles?
Bowman's Capsule
Spherical cluster capillaries within the renal Corpuscle
Glomerulus
Fluid enters from the Bowman's capsule to a series of?
Tubules
Tubules are divided into 3 sections
PCT, Loop of Henli, DCT
Several ___ drain into collecting ducts
Nephrons
3 main steps in urine production?
Filtration, Reabsorption, and Secretion
Blood enters the Nephron through
Afferent Arteriole
Blood drains From Glomerulus into
Efferent Arteriole
Hydrostatic Pressure in the glomerular capillaries forces fluid accros a filtration membrane formed by__
Endothelial Cells
of the capillary walls
Lamina Densa
Opening between processes of visceral epitheliun
Filtration slits
Glomeular Filtrate is similar to the composition of blood, but lacks these two?
Blood cells and Plasma Protein
Reabsorption begins when the filtrate enters the
PCT
In the PCT, 99% of organic nutrients are reabsorbed from filtrate?
Glucose and Amino acids
In the PCT, what are the ions needed that are reabsorbed
NA sodium, K potassium, Chloride, Bicarbonate
Forms a network around the renal tubule, receiving water and solutes as they are recovered from fitrate?
Peritubular Capillaries
Concentration of Urine due to?
Counter current Multiplication system in the loop of henli
Two hormones that affect the rate of reabsorption in the kidney.
ADH,Adosterone
Hormone from the renal cortex increases the rate of sodium reabsorption and potassium elimination
Aldesterone
Which follows the movement of NA+
Water
what does the flow from the
Peritubular Acpillaries flow through
Interlobular Veins
Interlobular Veins to?
Arcuate Vein
Arcuate Vein to
Interlobar Vein
Interlobar Vein to
Renal Vein
ABdominal Aorta to
Renal Artery
Renal Artery to
Interlobar artery
Interlobar Artery to
Arcuate Artery
Arcuate Artery to
Interlobular Artery
Interlobular artery to
Afferent Arteriole
Position of kidneys
Vertebrae T12 and L3
Function of kidney
Removal of metabolic waste from the blood and excretion out of body
Red blood cell production
EPO - Erythropoitin
Blood Pressure Regulation
Renin hormone
Calcium absorption
Calcitriol hormone
Fat and connective tissue of kidney 3 layers
Renal Capsule(fibrous)
Adipose capsule(fat)
Renal Fascia(kidney anchor to wall)
Leads from each kidney to Urinary Bladder
Ureters
Nephroptosis
Congenital loose kidney
thin people
not enough fat
Concave on medial side
Hilus
Hilus Drains 3 parts
Renal Vein, Artery, Ureter
Blood that passes to capillary walls into lumen of Bowman's Capsule
Glomerular Filtrate
Inflamation of renal Cortex
Glomerulonephritis
Immune response
Antigen-anti-body complexes
function of PCT
Reabsorption
What type of cells are the PCT made of?
Cuboidal cells
DCT functions
Secretion & Reabsorption
Collecting system
Transport tubular fluid to Pelvis
Collecting ducts receives
Tubular fluid from many nephrons
Papillary duct receives
Urine from several collecting ducts
urine pathway
Collecting duct->papillary duct-> minor Calyx->major calyx->renal pelvis->Ureter-> Urinary Bladder->Urethra-> out of body-> into toilet bowl
JGA
Juxtaglomerular Apparatus
Macula densa+juxtaglomerular cells
Function of JGA
secrete EPO
secrete Renin
when blood pressure is low
JG secretes
Renin and angiotensin system is activated and angiotensin is formed whichincreases Blood Pressure
VESA RECTA
capillary loops dip into medulla
cortical nephrons
shorter loop of henli and located mostly in the cortex
close to surface
Juxtaglomerullary nephrons
Longer loops of henli
near medulla
3 processes of urine formation
Glomerulus Filtration
Tubular reabsorption
Tubular secretion
Net Filtration Pressure
Forces in filtration between Capsular hydrostatic pressure and glomerular capillary osmotic pressure due to plasma protein
filtration pressure and rate
GFR & NFP - PROPOTIONAL
Reabsorption - tubule to blood
blood to tubule - secretion
normal pressure
35 mm hg
high pressure
60 mm hg
Liver -> Angiotensinogen
ACE inhibitor -> angiotensin 1 & 2
Increases ADH (anti-diuretic hormone)
Factors affecting GFR:
Shock, hemorrhage ->decreases BP and GFR
Heart failure-> decreases BP & GFR
Prostate enlargement->increase tubular pressure->decrease GFR
Hypertension-> increase BP and GFR
NA and water reabsorption
Osmosis reabsorbs na and other solute thrugh active transport
how many percent of the filtrate is reabsorbed
99%
Certain substances are reabsorbed
h20, ions, glucose, amino acids
in DCT, potassium and hydrogen may be passively be secreted in response to?
active reabsorption of sodium ions
ions in blood
K+ and H+
Wastes
Ammonia, Creatine
Other waste in bladder that is also released
Neurotransmitters
Histamine
some drugs
Why is the DCT and collecting ducts impermeable to water?
So water can be excreted in dilute urine
Role of ADH
water conservation/increase urine concentration/ water reabsorbed
If solute concentration is too High
Hypothalmus-> posterior pituitary gland-> increase plasma ADH ->increase water reabsoprtion
ADH more water reabsorbed
concentration of blood returns to normal
If solute concentration is too low then less ADH is secreted
Decrease in water reabsorbed and blood becomes more diluted(less water, more salt)
Diabetes Insipidus
Defieciency in ADH, constant drinking, water pass through
Counter Current Multplier
Helps maintain the NACL (salt)concentration gradient in the medullaary interstitial fluid
Fluid in ascending limb becomes..
hypotonic as solute is reabsorbed
Fuild in descending limb
hypertonic as it looses water by OSMOSSIS
Urine Composition
95% water, contains :
UREA(protein catabolism)
Uric Acid(Nucleic metabolism)
Creatine(loss of tissue)
TRace amount of amno acid and electrolyte, volume varies to intake and other conditions
ph of urine
4.5- 8.0 (normal 6.0)
Specific gravity of urine
1.003- 1.030
Volume of urine
1.2 liters a day
Color of urine
clear yellow
odor of urine
aromatic (varies)
Bacterial content of Urine
Sterile
Renal Clearance
rate at which chemical is removed from plasma
renal clearance test
inulin
plant polisaccharide
creatine clearance test
efficiency of GFR
efficiency of kidney
Para-aminoluppuric acid tes
calculate GFR
Length of Ureter
25 cm long extended downward posterior to the parietal peritoneum(retroperitoneal)
parallel to vertebral column
joined to urinary bladder
how does Urine flow in Ureter
Peristalsis and gravity
3 layers of wall of Ureter
Mucous coat
muscular coat-Transitional en.
fibrous coat
Urinary Bladder is located
within the pelvic region,
posterior to pubic symphysis
inferior to parietal peritoneum
Trigone
Triangular area inside urinary bladder by opening w/ 3 angle
Mucosa (urinary Bladder)
transistional epithelium , allows stretch
Submucosa(URINARY bLADDER)
connects mucosa to muscularis
Muscularis in urinary bladder
3 layers of smooth muscle
DETRUSOR MUSCLE
Tube that conveys urine from urinary bladder to the outside
Urethra
External uretral sphincter
Skeletal muscle
Voluntary
passes through the urogenital diaphragm
As detrusors contract the sphincters
relax
Acute Glomerulonephritis
occurs as an immun reaction to streptococus infection
occurs in cortical region or short loop of henli
Chronic Gromerulonephritis
progressive and may result into renal failure
Kidney stone
CALCULI - composed of calcium
Soundwaves used to break kidney stones
Lithotripsy- depends on location for application
Excessive urine output
Polyuria
Insufficient urine output
Olyguria
Painful urination
Dysuria
Protein in urine
Proteinuria
Blood in Urine
Hematuria
Due to mercaptan (sulfur containing compound foun in rotten eggs, garlic, etc
Asparagu urine
Urethra size
Female 3-5 cm and 18-20 in male
Urethra walls
Smooth muscles- mucosa membrane lining
function of ext. sphincter
Voluntary for both male and female
urethra pathway(reproductive ans urination)
Seaprate-female and together in male
Parts of Urethra
Female-single structure
Male- Prostatic,Membranous, Penile(cavernous)
Urination is also
Micturition
Urinary bladder can hold how much urine
1 liter
Average adult male has 40 liter of water
divided into 2 areas
intracellular fluid(2/3-63%)
extracellular fluid(1/3-37%)
Intracellular fluid have a high concentration of
Potassium, magnesium, phosphates, and sulfates
Extracellular fluid have a high concentration of
Sodium, calcium, Chloride, Bicarbonate
How much water intake is needed by humans?
2500 mm -drink
water loss
2500mm- through urine, skin, lungs, feces - 150ml(6%)
Dehydration causes ADH
to increase
Excess water intake causes ADH
to decrease
Salt and Water Hormone
Adosterone
Control of Aldosterone
REnin-Angiotensin pathway
Low blood (na+)
decrease in BP and GFR
Kidney renin increase
Stimulate adrenal cortex and increase aldosterone secretion
Na+ reabsorption at DCT
Leads to Excessive water and sodium loss from kidneys, increase potassium retention
Hyposecretion
Kidneys retain sodium and excrete potassium
Hypersecretion
food
fluids -->
metabolic reaction
Electrolyte intake->eletrolyte output ->persiratio,feces, urine
Strong Acids releases more?
Release more H+(hydrogen)
Weak acids
ionize more cmletely and release less OH(hydroxide)
Weak Base
Release few OH(Hydroxide)
Strong Base
increase release of H+ lower Ph,
ACidosis
Ph level goes below 7.5
Regulation of Hydrogen ions
Acid base buffer system
respiratory excretion of carbon dioxide
renal excretion of hydrogen ions
H20 output>h20 intake
Dehydration
increase sweating or decrease in water intake increases
concetration of ECF(solid less solvent water)
Elephantiasis
Lymphatic filiarsis - occlude lymphatic vessels