Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
159 Cards in this Set
- Front
- Back
Urine leaving kidneys, travels along the following pathway to the exterior?
|
Ureter, Urinary Bladder, Urethra
|
|
Which organ does not belong to the urinary system?
a:Urethra b:Gall Bladder c:Urinary Bladder d: Kidneys c: Ureters |
B: Gall Bladder
|
|
The initial factor which determines if urine production occurs is
a: Secretion, b:Absorption c: Sympathetic stimulation d: Filtration |
d: Filtration
|
|
Arrange in correct sequence from superior to deep?
a: Renal Capsule b:renal Medulla c:Renal Cortex, D: renal Pevis |
Capsule,cortex,medulla, pelvis
|
|
Name the structures that form the renal corpuscle?
|
Bowman's capsule, Glomerulus
|
|
Describe the filtration membrane. Arrange in order the layers that fluid or solutes pass through as they move from blood into the forming urine:
|
Fenestrated capillary wall, B.M. of Lamina Densa,
Filtration Slits |
|
what are the Filtration slits in the glomerulus?
|
Podocytes
|
|
Gromerular filtration is a process of pushing or Pulling? fluids and dilutes out of the glomerulus and into the fluid known as____?
|
pushing, Glomerular Filtrate
|
|
Name the waste product elliminated through urine?
|
urea, uric acid, NH4+
|
|
What does kidneys produce to regulate Blood Pressure?
|
Renin
|
|
Which product is vital to RBC production?
|
EPO (Erythropoietin
|
|
Which affects the Calcium absorption?
|
Calcitriol
|
|
What is the location of the kidneys?
|
Between T12 and L3 vertebrae
|
|
The ___ kidney is slightly superior to the___
|
Left and Right
|
|
The kidney are in the extreme anterior, or posterioir in the abdomen
|
Posterior
|
|
The kidneys are described as ___ since they are posterior to the peritoneum?
|
Retroperitoneal
|
|
The fnctional unit of the kidney
|
Nephron
|
|
microscope structures that are divided into two parts? in the nephron
|
renal corpuscle and renal tubule
|
|
Cuplike chamber of the renal corpuscles?
|
Bowman's Capsule
|
|
Spherical cluster capillaries within the renal Corpuscle
|
Glomerulus
|
|
Fluid enters from the Bowman's capsule to a series of?
|
Tubules
|
|
Tubules are divided into 3 sections
|
PCT, Loop of Henli, DCT
|
|
Several ___ drain into collecting ducts
|
Nephrons
|
|
3 main steps in urine production?
|
Filtration, Reabsorption, and Secretion
|
|
Blood enters the Nephron through
|
Afferent Arteriole
|
|
Blood drains From Glomerulus into
|
Efferent Arteriole
|
|
Hydrostatic Pressure in the glomerular capillaries forces fluid accros a filtration membrane formed by__
|
Endothelial Cells
|
|
of the capillary walls
|
Lamina Densa
|
|
Opening between processes of visceral epitheliun
|
Filtration slits
|
|
Glomeular Filtrate is similar to the composition of blood, but lacks these two?
|
Blood cells and Plasma Protein
|
|
Reabsorption begins when the filtrate enters the
|
PCT
|
|
In the PCT, 99% of organic nutrients are reabsorbed from filtrate?
|
Glucose and Amino acids
|
|
In the PCT, what are the ions needed that are reabsorbed
|
NA sodium, K potassium, Chloride, Bicarbonate
|
|
Forms a network around the renal tubule, receiving water and solutes as they are recovered from fitrate?
|
Peritubular Capillaries
|
|
Concentration of Urine due to?
|
Counter current Multiplication system in the loop of henli
|
|
Two hormones that affect the rate of reabsorption in the kidney.
|
ADH,Adosterone
|
|
Hormone from the renal cortex increases the rate of sodium reabsorption and potassium elimination
|
Aldesterone
|
|
Which follows the movement of NA+
|
Water
|
|
what does the flow from the
Peritubular Acpillaries flow through |
Interlobular Veins
|
|
Interlobular Veins to?
|
Arcuate Vein
|
|
Arcuate Vein to
|
Interlobar Vein
|
|
Interlobar Vein to
|
Renal Vein
|
|
ABdominal Aorta to
|
Renal Artery
|
|
Renal Artery to
|
Interlobar artery
|
|
Interlobar Artery to
|
Arcuate Artery
|
|
Arcuate Artery to
|
Interlobular Artery
|
|
Interlobular artery to
|
Afferent Arteriole
|
|
Position of kidneys
|
Vertebrae T12 and L3
|
|
Function of kidney
|
Removal of metabolic waste from the blood and excretion out of body
|
|
Red blood cell production
|
EPO - Erythropoitin
|
|
Blood Pressure Regulation
|
Renin hormone
|
|
Calcium absorption
|
Calcitriol hormone
|
|
Fat and connective tissue of kidney 3 layers
|
Renal Capsule(fibrous)
Adipose capsule(fat) Renal Fascia(kidney anchor to wall) |
|
Leads from each kidney to Urinary Bladder
|
Ureters
|
|
Nephroptosis
|
Congenital loose kidney
thin people not enough fat |
|
Concave on medial side
|
Hilus
|
|
Hilus Drains 3 parts
|
Renal Vein, Artery, Ureter
|
|
Blood that passes to capillary walls into lumen of Bowman's Capsule
|
Glomerular Filtrate
|
|
Inflamation of renal Cortex
|
Glomerulonephritis
|
|
Immune response
|
Antigen-anti-body complexes
|
|
function of PCT
|
Reabsorption
|
|
What type of cells are the PCT made of?
|
Cuboidal cells
|
|
DCT functions
|
Secretion & Reabsorption
|
|
Collecting system
|
Transport tubular fluid to Pelvis
|
|
Collecting ducts receives
|
Tubular fluid from many nephrons
|
|
Papillary duct receives
|
Urine from several collecting ducts
|
|
urine pathway
|
Collecting duct->papillary duct-> minor Calyx->major calyx->renal pelvis->Ureter-> Urinary Bladder->Urethra-> out of body-> into toilet bowl
|
|
JGA
|
Juxtaglomerular Apparatus
Macula densa+juxtaglomerular cells |
|
Function of JGA
|
secrete EPO
secrete Renin |
|
when blood pressure is low
JG secretes |
Renin and angiotensin system is activated and angiotensin is formed whichincreases Blood Pressure
|
|
VESA RECTA
|
capillary loops dip into medulla
|
|
cortical nephrons
|
shorter loop of henli and located mostly in the cortex
close to surface |
|
Juxtaglomerullary nephrons
|
Longer loops of henli
near medulla |
|
3 processes of urine formation
|
Glomerulus Filtration
Tubular reabsorption Tubular secretion |
|
Net Filtration Pressure
|
Forces in filtration between Capsular hydrostatic pressure and glomerular capillary osmotic pressure due to plasma protein
|
|
filtration pressure and rate
|
GFR & NFP - PROPOTIONAL
|
|
Reabsorption - tubule to blood
|
blood to tubule - secretion
|
|
normal pressure
|
35 mm hg
|
|
high pressure
|
60 mm hg
|
|
Liver -> Angiotensinogen
|
ACE inhibitor -> angiotensin 1 & 2
Increases ADH (anti-diuretic hormone) |
|
Factors affecting GFR:
|
Shock, hemorrhage ->decreases BP and GFR
Heart failure-> decreases BP & GFR Prostate enlargement->increase tubular pressure->decrease GFR Hypertension-> increase BP and GFR |
|
NA and water reabsorption
|
Osmosis reabsorbs na and other solute thrugh active transport
|
|
how many percent of the filtrate is reabsorbed
|
99%
|
|
Certain substances are reabsorbed
|
h20, ions, glucose, amino acids
|
|
in DCT, potassium and hydrogen may be passively be secreted in response to?
|
active reabsorption of sodium ions
|
|
ions in blood
|
K+ and H+
|
|
Wastes
|
Ammonia, Creatine
|
|
Other waste in bladder that is also released
|
Neurotransmitters
Histamine some drugs |
|
Why is the DCT and collecting ducts impermeable to water?
|
So water can be excreted in dilute urine
|
|
Role of ADH
|
water conservation/increase urine concentration/ water reabsorbed
|
|
If solute concentration is too High
|
Hypothalmus-> posterior pituitary gland-> increase plasma ADH ->increase water reabsoprtion
|
|
ADH more water reabsorbed
|
concentration of blood returns to normal
|
|
If solute concentration is too low then less ADH is secreted
|
Decrease in water reabsorbed and blood becomes more diluted(less water, more salt)
|
|
Diabetes Insipidus
|
Defieciency in ADH, constant drinking, water pass through
|
|
Counter Current Multplier
|
Helps maintain the NACL (salt)concentration gradient in the medullaary interstitial fluid
|
|
Fluid in ascending limb becomes..
|
hypotonic as solute is reabsorbed
|
|
Fuild in descending limb
|
hypertonic as it looses water by OSMOSSIS
|
|
Urine Composition
|
95% water, contains :
UREA(protein catabolism) Uric Acid(Nucleic metabolism) Creatine(loss of tissue) TRace amount of amno acid and electrolyte, volume varies to intake and other conditions |
|
ph of urine
|
4.5- 8.0 (normal 6.0)
|
|
Specific gravity of urine
|
1.003- 1.030
|
|
Volume of urine
|
1.2 liters a day
|
|
Color of urine
|
clear yellow
|
|
odor of urine
|
aromatic (varies)
|
|
Bacterial content of Urine
|
Sterile
|
|
Renal Clearance
|
rate at which chemical is removed from plasma
|
|
renal clearance test
inulin |
plant polisaccharide
|
|
creatine clearance test
|
efficiency of GFR
efficiency of kidney |
|
Para-aminoluppuric acid tes
|
calculate GFR
|
|
Length of Ureter
|
25 cm long extended downward posterior to the parietal peritoneum(retroperitoneal)
parallel to vertebral column joined to urinary bladder |
|
how does Urine flow in Ureter
|
Peristalsis and gravity
|
|
3 layers of wall of Ureter
|
Mucous coat
muscular coat-Transitional en. fibrous coat |
|
Urinary Bladder is located
|
within the pelvic region,
posterior to pubic symphysis inferior to parietal peritoneum |
|
Trigone
|
Triangular area inside urinary bladder by opening w/ 3 angle
|
|
Mucosa (urinary Bladder)
|
transistional epithelium , allows stretch
|
|
Submucosa(URINARY bLADDER)
|
connects mucosa to muscularis
|
|
Muscularis in urinary bladder
|
3 layers of smooth muscle
DETRUSOR MUSCLE |
|
Tube that conveys urine from urinary bladder to the outside
|
Urethra
|
|
External uretral sphincter
|
Skeletal muscle
Voluntary passes through the urogenital diaphragm |
|
As detrusors contract the sphincters
|
relax
|
|
Acute Glomerulonephritis
|
occurs as an immun reaction to streptococus infection
occurs in cortical region or short loop of henli |
|
Chronic Gromerulonephritis
|
progressive and may result into renal failure
|
|
Kidney stone
|
CALCULI - composed of calcium
|
|
Soundwaves used to break kidney stones
|
Lithotripsy- depends on location for application
|
|
Excessive urine output
|
Polyuria
|
|
Insufficient urine output
|
Olyguria
|
|
Painful urination
|
Dysuria
|
|
Protein in urine
|
Proteinuria
|
|
Blood in Urine
|
Hematuria
|
|
Due to mercaptan (sulfur containing compound foun in rotten eggs, garlic, etc
|
Asparagu urine
|
|
Urethra size
|
Female 3-5 cm and 18-20 in male
|
|
Urethra walls
|
Smooth muscles- mucosa membrane lining
|
|
function of ext. sphincter
|
Voluntary for both male and female
|
|
urethra pathway(reproductive ans urination)
|
Seaprate-female and together in male
|
|
Parts of Urethra
|
Female-single structure
Male- Prostatic,Membranous, Penile(cavernous) |
|
Urination is also
|
Micturition
|
|
Urinary bladder can hold how much urine
|
1 liter
|
|
Average adult male has 40 liter of water
|
divided into 2 areas
intracellular fluid(2/3-63%) extracellular fluid(1/3-37%) |
|
Intracellular fluid have a high concentration of
|
Potassium, magnesium, phosphates, and sulfates
|
|
Extracellular fluid have a high concentration of
|
Sodium, calcium, Chloride, Bicarbonate
|
|
How much water intake is needed by humans?
|
2500 mm -drink
|
|
water loss
|
2500mm- through urine, skin, lungs, feces - 150ml(6%)
|
|
Dehydration causes ADH
|
to increase
|
|
Excess water intake causes ADH
|
to decrease
|
|
Salt and Water Hormone
|
Adosterone
|
|
Control of Aldosterone
|
REnin-Angiotensin pathway
|
|
Low blood (na+)
|
decrease in BP and GFR
|
|
Kidney renin increase
|
Stimulate adrenal cortex and increase aldosterone secretion
Na+ reabsorption at DCT |
|
Leads to Excessive water and sodium loss from kidneys, increase potassium retention
|
Hyposecretion
|
|
Kidneys retain sodium and excrete potassium
|
Hypersecretion
|
|
food
fluids --> metabolic reaction |
Electrolyte intake->eletrolyte output ->persiratio,feces, urine
|
|
Strong Acids releases more?
|
Release more H+(hydrogen)
|
|
Weak acids
|
ionize more cmletely and release less OH(hydroxide)
|
|
Weak Base
|
Release few OH(Hydroxide)
|
|
Strong Base
|
increase release of H+ lower Ph,
|
|
ACidosis
|
Ph level goes below 7.5
|
|
Regulation of Hydrogen ions
|
Acid base buffer system
respiratory excretion of carbon dioxide renal excretion of hydrogen ions |
|
H20 output>h20 intake
|
Dehydration
|
|
increase sweating or decrease in water intake increases
|
concetration of ECF(solid less solvent water)
|
|
Elephantiasis
|
Lymphatic filiarsis - occlude lymphatic vessels
|