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20 Cards in this Set
- Front
- Back
describe the "micturition reflex"
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1. stretch receptors fire
2. signals are sent to Micturition Reflex Center [MRC] in pons to sacral spinal cord 3. parasympathetic impulses [detrusor muscle in bladder contracts, sphincter relaxes] 4. urine expelled 5. neurons of MRC fatigue, detrusor muscle relaxes |
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list the kidney functions
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1. urine formation [removes wastes & maintains fluid balance]
2. secrete erythropoietin [stimulates RBC formation] 3. regulate blood pressure 4. activate vitamin D |
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identify the gross anatomical features of the kidney
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renal capsule
renal hilum renal cortex renal medulla renal pyramids renal papilla renal calyx [major and minor] renal column |
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identify the microscopic functional unit of the kidney
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nephron: cortical & juxtamedullary
see handout! |
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trace the blood supply into and out of the kidney
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1. aorta
2. renal artery 3. segmental artery 4. lobar artery 5. interlobar artery 6. arcuate artery 7. interlobular artery 8. afferent arteriole 9. glomerulus [capillaries] 10. efferent arteriole 11. peritubular capillaries and vasa recta 12. interlobular vein/arcuate vein 13. arcuate vein 14. interlobar vein 15. renal vein 16. inferior vena cava |
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where does filtration occur?
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Bowman's capsule
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where does gas exchange occur?
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peritubular capillaries
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trace a drop of urine from its formation in Bowman's capsule to the ureter
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1. glomerulus
2. Bowman's capsule 3. proximal convoluted tubules 4. descending limb of Loop of Henle 5. ascending limb of Loop of Henle 6. distal convoluted tubule 7. connecting tubule 8. collecting ducts (cortical and medullary) 9. renal papillae 10. renal calyces (minor and major) 11. renal pelvis 12. ureter |
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define the term "renal corpuscle"
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the initial blood-filtering component of a nephron
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recognize normal components of urine
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95% water
5% solutes -nitrogenous wastes [urea --> comes from proteins; -uric acid --> comes from nucleic acids -creatine --> comes from muscular contractions] -electrolytes |
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recognize abnormal components of urine
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glucose [diabetes]
bilirubin [liver dysfunction] ketones [fat metabolism] blood [hematuria] leukocytes [infection] |
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list the 3 processes involved in the formation of urine
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1. glomerular filtration
2. tubular reabsorption 3. tubular secretion |
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define "glomerular filtration"
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movement of substances from glomerular blood into Bowman's capsule
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list the 3 sources of pressure contributing to Peff
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1. GHP [glomerular hydrostatic pressure)
2. GPOP [glomerulus plasma osmostic pressure] 3. CHP [capsular hydrostatic pressure] |
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in which direction does each source of pressure tend to push fluid?
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GHP -- OUT
GPOP -- IN CHP -- IN |
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list the factors involved in the control of filtration pressure (and how)
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1. juxtaglomerular apparatus: contact point between JG cells & the macula densa cells of the distal convoluted tubule [INCREASES glomerular filtration rate]
2. atrail naturiuretic peptide: hormone secreted by atria [INCREASES glomerular filtration rate] 3. neural regulation: sympathetic stimulation constricts afferent arterioles [DECREASES glomerular filtration rate] |
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list and define the 2 mechanisms of osmosis in the kidney... and which predominates
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obligatory osmosis: not hormonally controlled; happens in proximal convoluted tubule; constitutes 90% of water reabsorption [by laws of physics]
facultative osmosis: hormonally controlled; happens in distal convoluted tubule & collecting tubule; constitutes 10% of water reabsorption [what our kidneys can control] |
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list the mechanisms of action of Antidiuretic hormone (ADH) and Aldosterone
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ADH and aldosterone both increase water reabsorption!
ADH is produced by the pituitary gland & the tubule water permeability increases [starting in the ascending limb of the loop of Henle] by forming aquaporins [pores that allow water to pass through and leave] aldosterone is produced in the adrenal cortex & it increases sodium reabsorption, therefore water will follow |
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define "tubular reabsorption"
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things move from glomerular filtrate to peritubular capillaries
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define "tubular secretion"
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things move from the blood of peritubular capillaries into filtrate; rids body of excess
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