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26 Cards in this Set

  • Front
  • Back
Normal Flora of Upper Respiratory
Staphylococcus, Corynebacterium, Moraxella, Haemophilus, Bacteroides, Streptococcus
Protection of Upper Respiratory
Mucociliary escalator, Tonsils (lymphoid tissue), Macrophages in lungs, Lysosymes in tears, Eye Blinking
Common Cold
Rhinoviruses, Coronaviruses
nasopharynx, epithelial layer
Adenoviral Pharyngitis
70% sore throat cases= Viral
Inflammation of mucosa or lymphoid tissue (tonsillitis)
Cytomegalovirus
Common Characteristics
Largest Human herpes
dense DNA core
Herpesviridae
Cytomegalovirus
Mode of Transmission
Saliva, urine, blood, semen, cervical secretion, cross placental. Species Specific.
Cytomegalovirus
Virulence
interfere with MHC I
Induce Fc recp in infected cells
Hiding in infected cells
Epstein Barr Virus
Common Characteristics
Herpesviridae
Strain = viral capsid antigen (VCA)
Mononucleosis
Epstein Barr Virus
Pathogenesis
Attach B lymphocytes
CD21 receptors
Tc lymphocytes produced to attack B cells.
Epstein Barr Virus
Associated Diseases
Ubiquitous Disease
Lymphoma, Burkitt's Lymphoma (Africa)
Nasopharyngial Carcinoma
B cell lymphomas (immunodefi)
Burkitt's Lymphoma
Associated with Africa, and Papua New Guinea
Coinfection with Malaria
Strep Throat
Streptococcus pyrogenes
Group A hemolytic
Complications of Strep Throat
Scarlet Fever
Toxic Shock
Acute rheumatic Fever
Chorea
Glomerulonephritis
Scarlet Fever
Erythrogenic Strains of Strep. pyogenes
Exotoxin.
Strawberry Tongue.
Toxic Shock Syndrome
Associated with Strep pyogenes
SPE
Superantigen
Acute Rheumatic Fever
Strep pyogenes r/Strep Throat
Autoimmune vs. skin, joints, heart, kidneys
Chorea r/strep pyogenes/strepthroat
uncontrollable jerky movements
surface antigens close to human = host tissue destruction
Glomerulonephritis
Immune complex formed
disease of kidneys
block glomeruli = inflammation, high BP, loss proteins (IN URINE)
Diphtheria
Agent?
Vaccine?
Prominent Feature?
Corynebacterium diphtheriae
Exotoxin
Vaccine = Yes
Pseudomembrane in throat
Diphtheria
Mode of action?
Exotoxin
A-B
B Attach, A injected
A = ribosalation of EF-2
Possible Complications of Diphtheria
Conjunctivitis, Pharyngeal Membrane, Bull Neck, Severe Myocarditis
Conjunctivitis
Agent?
Haemophilus influenzae
Strept pneumoniae
Adenoviruses, Rhinoviruses
Otitis Media and Sinusitis
Haemophilus influenzae
Strept pneumoniae
Adenoviruses, Rhinoviruses
(commonly in conjunction with conjunctivitis)
Otitis Media
Prominent Feature
Bulging of Eardrum due to Eustachian tube inflammation
Candidiasis
Cause?
Immunocompression
Corticosteroid/antibiotic trmnt
AIDS, Diabetic, other
Candidiasis
Symptoms
Thrush (lips, gums, palate)
Whitish pseudomembranous tissue