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26 Cards in this Set
- Front
- Back
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Normal Flora of Upper Respiratory
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Staphylococcus, Corynebacterium, Moraxella, Haemophilus, Bacteroides, Streptococcus
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Protection of Upper Respiratory
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Mucociliary escalator, Tonsils (lymphoid tissue), Macrophages in lungs, Lysosymes in tears, Eye Blinking
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Common Cold
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Rhinoviruses, Coronaviruses
nasopharynx, epithelial layer |
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Adenoviral Pharyngitis
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70% sore throat cases= Viral
Inflammation of mucosa or lymphoid tissue (tonsillitis) |
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Cytomegalovirus
Common Characteristics |
Largest Human herpes
dense DNA core Herpesviridae |
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Cytomegalovirus
Mode of Transmission |
Saliva, urine, blood, semen, cervical secretion, cross placental. Species Specific.
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Cytomegalovirus
Virulence |
interfere with MHC I
Induce Fc recp in infected cells Hiding in infected cells |
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Epstein Barr Virus
Common Characteristics |
Herpesviridae
Strain = viral capsid antigen (VCA) Mononucleosis |
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Epstein Barr Virus
Pathogenesis |
Attach B lymphocytes
CD21 receptors Tc lymphocytes produced to attack B cells. |
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Epstein Barr Virus
Associated Diseases |
Ubiquitous Disease
Lymphoma, Burkitt's Lymphoma (Africa) Nasopharyngial Carcinoma B cell lymphomas (immunodefi) |
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Burkitt's Lymphoma
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Associated with Africa, and Papua New Guinea
Coinfection with Malaria |
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Strep Throat
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Streptococcus pyrogenes
Group A hemolytic |
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Complications of Strep Throat
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Scarlet Fever
Toxic Shock Acute rheumatic Fever Chorea Glomerulonephritis |
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Scarlet Fever
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Erythrogenic Strains of Strep. pyogenes
Exotoxin. Strawberry Tongue. |
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Toxic Shock Syndrome
Associated with Strep pyogenes |
SPE
Superantigen |
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Acute Rheumatic Fever
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Strep pyogenes r/Strep Throat
Autoimmune vs. skin, joints, heart, kidneys |
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Chorea r/strep pyogenes/strepthroat
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uncontrollable jerky movements
surface antigens close to human = host tissue destruction |
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Glomerulonephritis
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Immune complex formed
disease of kidneys block glomeruli = inflammation, high BP, loss proteins (IN URINE) |
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Diphtheria
Agent? Vaccine? Prominent Feature? |
Corynebacterium diphtheriae
Exotoxin Vaccine = Yes Pseudomembrane in throat |
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Diphtheria
Mode of action? |
Exotoxin
A-B B Attach, A injected A = ribosalation of EF-2 |
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Possible Complications of Diphtheria
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Conjunctivitis, Pharyngeal Membrane, Bull Neck, Severe Myocarditis
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Conjunctivitis
Agent? |
Haemophilus influenzae
Strept pneumoniae Adenoviruses, Rhinoviruses |
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Otitis Media and Sinusitis
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Haemophilus influenzae
Strept pneumoniae Adenoviruses, Rhinoviruses (commonly in conjunction with conjunctivitis) |
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Otitis Media
Prominent Feature |
Bulging of Eardrum due to Eustachian tube inflammation
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Candidiasis
Cause? |
Immunocompression
Corticosteroid/antibiotic trmnt AIDS, Diabetic, other |
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Candidiasis
Symptoms |
Thrush (lips, gums, palate)
Whitish pseudomembranous tissue |
