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230 Cards in this Set
- Front
- Back
Primate.
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Member of the mammalian order, including prosimians, monkeys, apes and humans, defined by a suite of anatomical and behavioral traits.
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Evolution.
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A change in the frequency of a gene or a trait in a population over multiple generations.
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Biological Anthropology
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The study of humans as biological organisms, considered in an evolutionary framework.
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Physical Anthropology.
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Also known as Biological Anthropology
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Hominid.
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A member of the primate family Hominidae, distinguished by bipedal posture and, in more recently evolved species, large brain.
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Adaptation.
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A trait that increases the reproductive success of an organism, produced by natural selection in the context of a particular environment.
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Anthropology.
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The study of humankind in a cross-cultural context.
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CLAP: Cultural, Linguistic, Archaeology & Physical/Biological
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What are the 4 subfields of Anthropology?
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culture.
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The sum total of learned traditions, values, and beliefs that groups of people (and a few species of highly intelligent animals) possess.
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What does LTVB represent?
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Learned Traditions, Values and Beliefs that is defined as culture.
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Biocultural Anthropology.
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The study of the interaction between biology and culture, which plays a role in most human traits.
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Paleoanthropology.
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The study of the fossil record of ancestral humans and their primate kin.
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Osteology.
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The study of the skeleton.
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Paleopathology.
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The study of the diseases in ancestral human populations.
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Forensic Anthrolopology.
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The study of human remains applied to a legal context. - Identifying victims of genocide, murder or disasters.
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Laetoli in Northern Tanzania.
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Where were the ancient human-like footprints found in fossilized ash?
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Primatology
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The study of the nonhuman primates; their anatomy, genetics, behavior, and ecology.
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Jane Goodall.
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Who is the famous primatologist that studied chimps in the 60's and 70's?
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Physical Anthropology.
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The study of humans as biological organisms, considered in an evolutionary framework.
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What is the importance of falsifiability?
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When an hypothesis is falsifiable it can never be proven 100%. This allows for reworkings of the hypothesis to fit future data and discovery.
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Falsifiability
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What must a theory or hypotheis have to be scientifically studied?
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paradigm.
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A conceptual framework useful for understanding a body of evidence.
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Linnaean system. Carolus Linnaeus built on John Ray's work to create his comprehensive classification system.
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What is the name of the classification system used in the biological sciences today? And who invented it?
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taxonomy.
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The science of biological classification.
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Binomial Nomenclature.
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Linnaean naming system for all organisms, consisting of a genus and species label.
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Binomial Nomenclature.
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What is the two word Linnaean naming system called?
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James Ussher.(Anglican Archbishop). *4004 BC God Usshered his creatures onto the earth*
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Who set the year of creation at 4004 BC?
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fixity or immutability of species.
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What is the opposite of evolutionary changes in species?
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What is so revolutionary about the idea of evolution - especially in the 1700's?
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Evolution is counter to the idea of the immutability of species which follows from a single creation event.
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Was Darwin the first naturalist to propose the evolution of species?
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No, other naturalists put forth various theories that were counter to the widely held beliefs of the immutability of species.
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Who drew on his observations of the New World to posit the idea of species changing in response to their environments?
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Comte de Buffon - said New World animals inferior to old. *Jefferson made him out to be a buffoon for saying Europe's evolved to be better than J's
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George Cuvier *God created all the species but sometimes a Curve-ball would get past him (like a meteorite) and He'd have to start all over again.
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Who was a staunch creationist that explained away dinosaur bones with the concept of Catastrophism?
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Catastrophism.
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Theory that there have been multiple creations interspersed by great natural disasters such as Noah's flood.
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Geoffroy Saint-Hilaire correctly identified what Cuvier thought was a crocodile as a fossil. *Hilaire thought Cuvier's catastrophism was hilarious
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.Who was the brilliant anatomist that made Cuvier look foolish over a fossil?
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theory of inheritance of acquired characteristics. *Lamarck's theory says that permanent marker on the mother will show up in the same place on her baby.
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What was Jean-Baptiste Lamarck's theory to explain the evolution of species?
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Discredited theory of evolutionary change proposing that changes that occur during the lifetime of an individual, through use or disuse, can be passed on to the next generation.
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What is the Theory of Inheritance of Acquired Characteristics?
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Uniformitarianism.
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Theory that the same gradual geological processess we observe today were operating in the past.
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James Hutton and Charles Lyell. *It's not Rock Hudson! it's James Hutton who's the father of geology *Lyell showed that it took geological processes a Lllllong time to form the earth we see now.
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Who were the uniformitarians?
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James Hutton and Charles Lyell. *It's not Rock Hudson! it's James Hutton who's the father of geology *Lyell showed that it took geological processes a Lllllong time to form the earth we see now.
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Who are the important influences of Darwin's from geology?
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Because their uniformitarianism presumed a much older earth than the biblical reckoning of 6000 years.
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Who are the important influences of Darwin's from geology?
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Giant tortoises with different shells - depending on the islands they were confined to.
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Besides the finches, what other interestingly variable species did Darwin discover on the Galapagos?
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It was actually John Gould back in London who sorted the finches and discovered their were 11 species.
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How many different finches did Darwin identify on the Galapagos?
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adaptive radiation.
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The diversification of one founding species into multiple species and niches.
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Natural Selection.
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Differential reproductive success over multiple generations.
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Alfred Russel Wallace?
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A naturalist who's theory of evolution was very close to Darwin's.
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1 - Variations in a trait exist or individuals of a species vary.
2 - Variations are heritable 3 - Different traits yield differential reproductive success. |
What are the three main principles of Darwin's natural selection?
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Fitness.
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Reproductive success.
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population.
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An interbreeding group of organisms.
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mutation.
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An alteration in the DNA that may or may not alter the function of a cell. If it occurs in a gamete, it may be passed from one generation to the next.
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creation science?
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A creationist attempt to refute the evidence of evolution. (Creation science is an oxymoron, i.e. creationism is not science).
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Why is creationism not science?
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Because the hypothesis that something beyond observation created or helped to create the natural world is not falsifiable.
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intelligent design?
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A creationist school of thought that proposes that natural selection cannot account for the diversity and complexity of form and function seen in nature.
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pedigree.
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A diagram used in the study of human genetics that shows the transmission of a genetic trait over generations of a family.
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Telomeres - are pieces of DNA that cap the ends of chromosomes. As an individual ages, the telomeres shorten. A cloned adult passes the already shortened telomeres to the 'offspring'.
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What are the structures called that may be responsible for the shortened lifespan of clones.
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Prokaryotes do not have a nucleus and EUkaryotes have a neclEUs.
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Which type of cells have a nucleus and which do not?
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Prokaryotes.
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Single-celled organisms, such as bacteria, in which the genetic material is not separated from the rest of the cell by a nucleus.
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Cytoplasm?
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In a eukaryotic cell, the region within the cell membrane that surrounds the nucleus; it contains organelles, which carry out the essential functions of the cell, such as energy production, metabolism, and protein synthesis.
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Bacteria and blue-green algae.
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Name two Prokaryotes.
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Somatic Cells?
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The cells of the body that are not sex cells or gametes.
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Gametes?
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The sex cells; sperm in males and eggs (or ova) in females.
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Stem Cells?
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Undifferentiated cells found in the developing embryo that can be induced to differentiate into a wide variety of cell types or tissues.
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Organelles?
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Various structures found iin the cytoplasm of a eukaryotic cell that help maintain the cell and carry out its functions.
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totipotent stem cell can differentiate into any of the somatic cell types.
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What does it mean to say that a cell is Totipotent?
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olfactory mucosa lining of the nasal passages.
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From what part of the (adult) human body have scientists recovered stem cells?
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Deoxyribonucleic Acid (DNA)
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A double-stranded molecule that is the carrier of genetic information. Each strand is composed of a linear sequence of nucleotides; the two strands are held together by hydrogen bonds that form between complementary bases.
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Proteins.
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What are the structural molecules that transport molecules, antibodies, enzymes and hormones?
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proteins
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Complex molecules formed from chains of amino acids (polypeptide) or from a complex of polypeptides. They function as structural molecules and transport molecules, antibodies, enzymes and hormones.
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Protein Synthesis
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The assembly of proteins from amino acids that occurs at ribosomes in the cytoplasm and is based on information carried by mRNA.
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Ribonucleic Acid (RNA)
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Single-straded nucleic acid that performs critical functions during protein synthesis and comes in three forms:
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Messenger RNA, transfer RNA, and ribosomal RNA.
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What are the the three forms of RNA?
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Mitochondria
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Organelles in the cytoplasm of the cell where energy production for the cell takes place. Contains its own DNA.
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Endoplasmic Reticulum
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An organelle in the cytoplsam consisting of a folded membrane.
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Ribosomes
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Structures composed primarily of RNA that are found on the endoplasmic reticulum. They are the site of protein synthesis.
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nucleotide
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Molecular building block of nucleic acids DNA and RNA; consists of a phospate, sugar, and base.
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A phosphate, sugar and base. (The bases can be either adenine, guanine, thymine or cytosine in DNA or uracil - that replaces thymine - in RNA.)
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What are the three parts of a nucleotide?
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base
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Variable component of the nucleotides that form the nucleic acids DNA and RNA.
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Adenine, guanine, thymine and cytosine. *All Tots Can Grow
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What are the bases in DNA?
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Adenine, guanine, uracil and cytosine
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What are the bases in RNA?
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Enzyme
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A complex protein that is a catalyst for chemical processes in the body.
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A & T G & C
(A & T made of straight lines; G & C out of curved) |
What are the base pairs in DNA?
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A & U G & C
U comes after T |
What are the base pairs in RNA?
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Hemoglobin
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Protein found in red blood cells that transports oxygen.
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Hormone
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A natural substance (often a protein) produced by specialized cells in one location of the body that influences the activity or physiology of cells in a different location.
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amino acids
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Molecules that form the basic building blocks of protein.
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20.
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How many amino acids are there?
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9 (3x3)
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How many amino acids are essential - they cannot be synthesized by the body and must be obtained from diet?
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They cannot be synthesized by the body and must be obtained from diet.
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What makes an amino acid 'essential'?
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Adenosine Triphospate (ATP) an energy rich molecule to power the activities of the cell.
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What do mitochondria produce?
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Adenosine Triphosphate (ATP)
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An energy rich molecule produced by the mitochondria to power the activities of the cell.
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It provides increased surface area within the cell for metabolic reactions to take place.
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What is the importance of the folded-sheet structure of the endoplasmic reticulum?
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A Nucleotide consiting of a sugar, a phospate group and a nitrogenous base.
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What is the most basic building block of DNA?
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Watson and Crick
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Who formulated the model of DNA as a double helix?
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Hydrogen bonds.
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What holds the A-T and C-G pairings together in DNA?
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Self-replication and protein synthesis.
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What are the two functions of DNA?
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Yes
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Is Hemoglobin a protein?
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Yes
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Are Hormones a protein?
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Enzymes.
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What are the largest class of protiens in the body?
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amino acids chain.
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What are proteins made up of?
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polypeptide.
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A molecule made up of a chain of amino acids is called a?
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Genetic Code
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The system whereby the nucleotide triplets in DNA and RNA contain the information for synthesizing proteins from the twenty amino acids.
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If DNA only has 4 different bases for coding how does it code for 20 different amino acids?
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A sequence of 3 bases codes for each amino acid. The three base sequences are called codons.
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Codon
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A triplet of nucleotide bases in mRNA that specifies an amino acid or the intiation or termination of a polypeptide sequence.
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Gene
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The fundamental unit of heredity. Consists of a sequence of DNA bases that carries the information for synthesizing a protein (or polypeptide), and occupies a specific chromosomal locus.
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Besides coding for amino acids what else do codons code?
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Three codons signal that the protein chain is ending. One codon (TAC) codes for the amino acid methionine and also servies as an initiation codon.
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Transcription then translation.
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What is the two step process for synthesizing a protein?
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Nucleus
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Where is Transcription of the protein is done in the cell? and translation is done in the
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cytoplasm.
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Where is translation of the protein is done in the cell?
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messenger RNA (mRNA).
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What carries the transcription of a protein out of the nucleus of a cell to the cytoplasm for translation?
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transfer RNA (tRNA)?
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RNA molecules that bind to specific amino acids and transport them to ribosomes to be used during protein synthesis.
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Ribosomes.
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Where in the cytoplasm does protein synthesis occur?
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no
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Does all DNA code for something?
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Chromatin.
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The diffuse form of DNA as it exists during the interphase of the cell cycle.
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mitosis and meiosis
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When does DNA go from a dispersed state (chromatin) to forming chromosomes?
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Mitosis
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Somatic cell division in which a single cell divides to produce two identical daughter cells.
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Meiosis?
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Cell division that occurs in the testes and ovaries that leads to the formation of sperm and ova (gametes).
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chromosome?
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Discrete structures composed of condensed DNA and supporting proteins.
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For humans there are 23 pairs of different chromosomes in every cell except the gametes. 46 since we're a Dipolid organism.
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Who many chromosomes are present in every cell?
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One from the mother and one from the father.
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Since most organisms have two copies of each chromosome: where does each copy come from?
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Centromere?
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Condensed and constricted region of a chromosome. During mitosis and meiosis, location where sister chromatids attach to one another.
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Diploid number?
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What is the Full complement of paired chromosomes in a somatic cell number called ? 46 (23 pairs of different chromosomes).
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Haploid number?
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the number of chromosomes found in a gamete, representing one from each pair found in a diploid somatic cell. In humans the number is 23.
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Homologous Chromosomes?
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Members of the same pair of chromosomes (or autosomes).
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locus?
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The location of a gene on a chromosome.
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alleles?
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Alternative versions of a gene. Different alleles are distinguished from one another by their different effects on the phenotypic expression of the same gene.
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Homozygous.
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Having the same allele at the loci for a gene on both members of a pair of homologous chromosomes (or autosomes).
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Heterozygous.
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Having two different alleles at the loci for a gene on a pair of homologous chromosomes (or autosomes).
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Interphase.
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What is the cell phase called between times of mitosis?
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Prophase - pre-phase
Metaphase - orderly line up in center (*military lineup) Anaphase - split up and go to opposite sides (*shows animosity) Telophase - split into two cells with own cytoplasm (they can still telephone) |
What are the 4 phases of mitosis?
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Zygote?
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A fertilized egg.
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Crossing Over?
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Exchange of genetic material between homologous chromosomes during the first prophase of meiosis; mechanism for genetic recombination.
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Recombination?
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The rearrangement of genes on homologous chromosomes that occurs during crossing over in meiosis. Source of variation arising out of sexual reproduction; important for increasing rates of natural selection.
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Only in the testes of males and ovaries of women.
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Where does Meiosis happen?
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Karyotype?
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The complete chromosomal complement of an individual: usually based on a photograph of the chromosomes visualized under the microscope.
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Autosomes?
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Any of the chromosomes other than the sex chromosomes.
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Sex Chromosomes?
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In mammals chromosomes X and Y, with XX producing Females and XY producing males.
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Nondisjunction Error?
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The failure of homologous chromosomes (chromatids) to separate properly during cell division. When it occurs during meiosis, it may lead to the formation of gametes that are missing a chromosome or have an extra copy of a chromosome.
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24 chromosomes.
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What is the Haploid number of chromosomes in human's closest living relative; the chimpanzee?
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Monosomy - missing a chromosome as in Turner Syndrome
Trisomy - an extra chromosome is present as in Down Syndrome. |
What are the two common kinds of nondisjunction errors?
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Turner syndrome
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What nondisjunction error syndrome results from a missing chromosome (or monosomy) in the gamete - an X or Y is missing and the female is XO exhibiting delayed maturation, small stature.
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Down syndrome
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What nondisjunction error syndrome is also known as trisomy 21 occurs when indvidual has three copes of chromosome 21 rather than 2.
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Genome?
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The sum total of all the genes carried by an individual.
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Polymerase Chain Reaction (PCR)?
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Method for amplifying DNA sequences using the Taz polymerase enzyme. Can potentially produce millions or billions of copies of a DNA segment starting from a very small number of target DNA.
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Mitochondrial DNA (mtDNA).
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Small loop of DNA found in the mitochondria. It is clonally and maternally inherited.
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Because the regions of the mtDNA genome (such as the D loop) that do not code for anything are highly variable and can point to evolutionary patterns between populations or even members of populations. (and there is no crossing over)
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Why is mitochondrial DNA used by bioanthropologists.
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Because it is found in the cytoplasm of the egg and in the tail of a sperm - which is lost (the tail) upon fertilization of the egg.
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Why is mitochondrial DNA only passed on through the mother?
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Structural Genes?
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Genes that contain the information to make a protein.
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Regulatory genes?
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Guide the expression of structural genes, without coding for a protein themselves.
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Genotype.
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The genetic makeup of an individual. Can refer to the entire genetic complement or more narrowly to the alleles present at a specific locus on two homologous chromosomes.
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Phenotype.
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An observable or measurable feature of an organism. Can be anatomical, biochemical, or behavioral.
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ABO blood type system.
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Refers to the genetic systme for one of the proteins found on the surface of red blood cells. Consists of one gene with three alleles: A, B, and O.
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Recessive.
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In a diploid organism, refers to an allele that must be present in two copes (homozygous) in order to be expressed.
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Dominant.
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In a diploid organism, an allele that is expressed when present on only one of a pair of homologous chromosomes.
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Codominant.
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In a diploid organism, two different alleles of a gene that are both expressed in a heterozygous individual.
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Particulate Inheritance.
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The concept of heredity based on the transmission of genes (alleles) according to Mendelian principles.
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Mendel's four postulates or laws?
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1 - Heritable characteristics are controlled by particulate unit factors that exist in pairs.
2 - There are dominant and recessive particulate units. 3 - Mendel's law of Segregation 4 - Mendel's law of Independent Assortment |
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Mendel's law of Segregation?
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The two alleles of a gene found on each of a pair of chromosomes segregate independently of one another into sex cells.
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Mendel's law of independent assortment?
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Genes found on different chromosomes are sorted into sex cells independently of one another.
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Linkage?
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Genes that are found on the same chromosome are said to be linked. The closer together two genes are on a chromosome, the greater the linkage and the less likely they are to be separated during crossing over.
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Point Mutation?
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A change in the base sequence of a gene that results from the change of a single base to a different base.
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Sickle Cell Disease?
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An autosomal recessive disease caused by a point mutation in an allele that codes for one of the polypeptide chains of the hemoglobin protein.
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Autosomal recessive disease?
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A disease caused by a recessive allele; one copy of the allele must be inherited from each parent for the disease to develop.
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Insertion Mutation?
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A change in the base sequesnce of a gene that results from the addition of one or more base pairs in the DNA.
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Deletion Mutation?
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A change in the base sequence of a gene that results from the loss of one or more base pairs in the DNA.
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Trinucleotide Repeat Diseases?
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A family of autosomal dominant diseases that is caused by the insertion of multiple copies of a three-base pair sequence (CAG) that codes for the amino acid glutamine. Typically, the more copies inserted into the gene, the more serious the disease.
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Autosomal Dominant Disease?
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A disease that is caused by a dominant allele. Only one copy needs to be inherited from either parent for the disease to develop.
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X-linked Disorders?
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Genetic conditions that result from mutations to genes on the X chromosome. they are almost always expressing in males, who have only one copy of the X chromosome; in females, the second X chromosome containing the normally functioning allele protects them from developing X-linked disorders.
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Cystic Fibrosis, Sickle Cell Disease, Tay-Sachs Disease and Phenylketonuria (PKU)
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Name 4 Autosomal Recessive Disorders.
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Huntington Disease, Neurofibromatosis type I
Myotonic dystrophy (form of musculor distrophy) Achondroplasia (form of dwarfism) |
Name 4 Autosomal Dominant Disorders.
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Fragile X syndrome (severe mental retardation)
Hemophilia (bleeding disease) Lesch-Hyhan syndrome (overproduction of uric acid) |
Name 3 X-Linked Disorders.
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Good in Birth or Noble in Heredity
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From what Greek root meaning did the term Eugenics derive?
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Qualitative Variation.
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Phenotypic variation that can be characterized as belonging to discrete, observalbe categories.
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Polygenic Traits?
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Phenotypic traits that result from the combined action of more than one gene; includes most complex traits
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continuous variation for a trait
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When the trait is caused by polygenic inheritance rather than a single gene effect it is called?
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Qualitative variation.
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When phenotypes are different and nonoverlapping - either/or; what type of variation is this?
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Quantitative variation.
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When phenotypes are overlapping or continuous - appear on a continuum; what type of variation is this?
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pleiotropy.
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The phenomenon of a single gene having multiple phenotypic effects.
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heritability.
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The proportion of total phenotypic variability observed for a given trait that can be ascribed to genetic factors.
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Phenylketonuria (PKU).
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Autosomal recessive condition that leads to the accumulation of large quantities of the amino acidi phenylalanine, causing mental retardation and other phenotypic abnormalties.
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natural selection.
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Differential reproductive success over multiple generations.
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Directional selection.
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Natural selection that drives evolutionary change by selecting for greater or lesser frequency of a given trait in a population.
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Stabilizing Selection.
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Selection that maintains a certain phenotype by selecting against deviations from it.
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Gene Flow.
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Movement of genes between populations.
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Inbreeding.
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Mating between close relatives.
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Genetic Drift
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Random changes in gene frequency in a population.
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Founder Effect?
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A component of genetic drift theory, stating that new populations that become isolated from the parent population carry only the genetic variation of the founders is what effect.
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Genetic Bottleneck?
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Temporary dramatic reduction in size of a population or species. (Gene pool reduction)
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Sexual Selection?
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Differential reproductive success within one sex of any species.
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Sexual Dimorphism?
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Difference in size, shape, or color, between the sexes.
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Reproductive Potential?
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The possible offsptring output by one sex.
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Reproductive Variance.
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A measure of variation from the mean of a population in the reproductive potential of one sex compared with the other.
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systematics?
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Branch of biology that describes patterns of oranismal variation. (Taxonomy)
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Homology.
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Similarity of traits resulting from shared ancestry.
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Analogous.
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Having similar traits due to similar use, not due to shared ancestry.
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Convergent (or Parallel) Evolution
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Similar form or function brought about by natural selection undder similar environments rather than shared ancestry.
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Cladogram?
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Branching diagram shwoing evolved relationshps among members of a lineage.
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Species?
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An interbreeding group of animals or plants that are reproductively isolated through anatomy, ecology, behavior, or geographic distribution from all other such groups.
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Speciation?
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Formation of one or more new speices via reproductive isolation.
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Biological species concept
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Defines species as interbreeding populations reproductively isolated from other such populations.
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Recognition species concept
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Defines species based on unique traits or behaviors that allow members of one species to identify each other for mating.
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Premating Isolating mechanisms (4)
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Habitat isolation, Temporal isolation, Behavioral isolation, Mechanical incompatibility.
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temporal isolation?
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When the different species breed in different seasons, different months or different times of day.
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habitat isolation?
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When the different species occupy different habitats such as the canopy vs the forest floor.
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behavioral isolation?
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Courtship rituals or other mating behavior that differs from species to species.
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mechanical incompatibility?
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When the different species cannot mate successfully because of anatomical differences.
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Reproductive Isolating Mechanisms (RIMs)
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Any factor - behavioral, ecological, or anatomical - that prevents a male and female of two different species from hybridizing.
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Postmating Isolating Mechanisms (4)
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Sperm-egg incompatibility,
Zygote inviability Enbryonic or fetal inviability Offspring inviability (dies after birth) Offspring sterility |
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Anagenesis.
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Evolution of a trait or a speices into another over a period of time.
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Cladogenesis.
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Evolution through the branching of a species or a lineage.
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Allopatric Speciation?
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Speciation occuring via geographic isolation. (gALLaPOgos isolated islands)
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Parapatric Speciation?
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Speciation occurring when two populations have continuous distributions and some phenotypes in that distribution are more favorable than others.
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Gradualism?
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Darwinian view of slow, incremental evolutionary change.
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Macroevolution.
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Large-scale evolutionary change over a long time period.
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Punctuated equilibrium.
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Model of evolution characterized by rapid bursts of change, followied by long periods of stasis.
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Adaptationism.
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A premise that all aspects of an organism have been molded by natural selection to a form optimal for enhancing reproductive success.
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reductionism.
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Paradigm that an organism is the sum of many evolved parts and that organisms can best be understood through an adaptationist approach.
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Null Hypothesis?
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the starting assumption for scientific inquiry that one's research results occur by random chance. One's hypothesis must challenge this initial assumption.
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Hardy-Weinberg equilibrium?
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The theoretical distribution of alleles in a given population in the absence of evoultion, expressed as a mathematical equation.
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Hardy Weinberg ratio:
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for A and B alleles
p for frequency of A and q for frequency of B AA = p squared AB = 2pq BB = q squared |
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group selection?
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Notion (largely discredited by the rise of of Darwinian theory) that proposes that animals act for the good of their social group or their species.
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Is group selection valid - what type of 'selection' explains altruism?
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Group selection is not valid but kin selection or inclusive fitness explains altruistic acts by members of a species.
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kin selection?
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Principle that animals behave preferentially toward their genetic kin; formulated by William Hamilton.
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William Hamilton?
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Introduced idea of kin selection or inclusive fitness.
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Sociobiology.
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What field of study incorporates the concepts of kin selection and inclusive fitness?
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inclusive fitness?
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Reproductive success of an organism plus the fitness of its close kin.
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Which kin share 50% of their genes?
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Parent/child; sibling/sibling.
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50%
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What percentage of genes does a parent share with it's child?
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50%
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What percentage of genes do siblings share?
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25%
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What percentage of genes does an Aunt or Uncle share with it's Niece or Nephew?
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25%
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What percentage of genes does a grandparent share with it's grandchild?
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12.5% or 1/8th
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What percentage of genes do first cousins share?
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