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18 Cards in this Set

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What is "the cell theory of disease"?
The idea that disease are accompanied by consistent changes in the types and populations of cells in tissues.
What are the seven classes of disease, as given in lecture?
Vascular and hemodynamic, inflammatory, infectious, immunologic, neoplasia and other growth disorders, genetic, and environmental.
What is ischemia? How is that different from anoxia?
Lack of oxygenated blood in the tissues. Anoxia is just lack of oxygen in the tissue.
What are some effects of ischemia?
Lack of oxygen, glucose, and other metabolic substrates.
What is infarction?
Necrosis of tissue due to the lack of blood supply.
What is one means the body has of adapting to ischemia?
Cell atrophy (shrinkage).
What is inflammation?
A shift of fluids and cells from the blood into the surrounding tissues.
What is chronic inflammation frequently caused by?
Alterations in tissue structure.
What suffix is used to denote inflammatory diseases?
-itis.
What are two common causes of inflammation?
Infection and immunologic mechanisms.
What is meant by an infectious disease?
One where organisms invade or damage tissues.
What kind of organisms can be involved in infectious disease?
Bacteria, viruses, fungi, protozoa, worms, and occasionally algae.
What is immunologic disease?
An exaggerated immune response, where the body attacks the tissues as though they were an invading microorganism.
What does "neoplasia" mean?
New growth. This is essentially synonymous with the word tumor.
What is hyperplasia?
Englargement of tissues by cell multiplication.
What is hypertrophy?
Enlargement of tissue via an increase in the size of the cells.
What are storage diseases?
When there is a lesion in a metabolic pathway (example given is a genetic lesion), causing the buildup of an abnormal metabolic byproduct.
What are some examples of environmental disease?
Nutritional disease, chemical toxicity, trauma, and many iatrogenic disease.