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26 Cards in this Set
- Front
- Back
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Fecal leukocytes are indicative of what?
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Inflammation
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Ulcerative colitis is confined to what area?
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Colon - mucosa & submucosa
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What is the location of Crohn's?
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Anywhere in GI tract
May be transmural |
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What is the most common age range to be diagnosed with IBD?
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20s
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What is the hallmark of ulcerative colitis?
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Bloody diarrhea
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Tenesmus, weight loss, bloody diarrhea, and abdominal pain are indicative of what?
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Ulcerative colitis
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What is the most common location for UC?
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Distal/left sided colitis (40%)
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What is the most common location for Crohn's?
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Ileocolitis (40%)
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Perianal disease, diarrhea, and chronic abdominal pain and tenderness are indicative of what?
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Crohn's disease
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After how many years of having the disease should UC patients get frequent colonoscopies?
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10 years
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What does transmural mean?
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Going all the way through the intestinal wall
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What are the skin complications of IBD?
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Erythema nodosum
Pyoderma gangrenosum |
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What are the joint disorders associated with IBD?
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Peripheral arthritis
Sacroiliitis Ankylosing spondylitis |
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What are common hepatobiliary complications of IBD?
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Gallstones
Sclerosing cholangitis Cholangiocarcinoma |
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What is the therapy for mild IBD?
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Aminosalicylates (1st line)
Antibiotics Oral corticosteroids Elemental diets |
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What is the therapy for moderate IBD?
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Oral/parenteral corticosteroids
Elemental diets Antimetabolites |
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What is the therapy for severe IBD?
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Infliximab
Parenteral corticosteroids Bowel rest Surgery |
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What drugs are effective for UC?
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Sulfasalazine
Olsalazine (Dipentum) Mesalamine (Asacol) delayed release Mesalamine (Pentasa) controlled release |
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What is the maintenance therapy of remission of distal UC?
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Topical mesalamine
Aminosalicylates |
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What are the drugs used for maintenance of remission for moderate extensive colitis?
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Oral aminosalicylates
Oral azathioprine or 6-mercaptopurine |
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What are the drugs used for management of severe UC?
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IV steroids
IV infliximab |
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What drugs are used for management of mild-moderate distal UC?
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Oral aminosalicylates
Topical mesalamine Topical steroids |
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What drugs are used for management of mild-moderate extensive UC, active disease?
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Oral aminosalicylates
Oral prednisone Oral azathioprine or 6-mercaptopurine |
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What are the drugs for management of severe colitis?
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IV steroids
IV infliximab IV cyclosporine Surgery |
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What are the drugs used for treatment of mild-moderate active Crohn's?
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Oral aminosalicylates
Antibiotics - Metronidazole, Ciprofloxacin Budesonide |
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What are the drugs used for treatment of moderate-severe active Crohn's?
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Prednisone
Immunomodulators - azathioprine/6-MP, methotrexate Anti-TNF therapy - infliximab, certolizumab, adalimumab |
