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42 Cards in this Set
- Front
- Back
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What factors are affected with the PT and PTT are both elevated?
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Common pathway
Factors I, II, V, X or multiple factor deficiencies Coumadin therapy |
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Fibrin monomers break down to what?
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FDP
D-Dimer |
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Which tests are prolonged in DIC?
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PT
PTT |
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The blood in hemolytic disease of the newborn shows what?
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Nucleated RBCs
Erythroblasts |
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What does a "shift to the left" mean?
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Blood contains more immature neutrophils
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Rh antibodies are usually which Ig?
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IgG, warm reacting
don't activate complement |
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Protein C inactivates what factors?
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Factors V and VIII
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Which pathways does the PT measure?
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extrinsic & common
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Which Rh is most antigenic?
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D
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What converts plasminogen to plasmin?
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TPA
plasminogen activators |
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What are the tests for fibrinolysis?
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FDP
D-Dimer |
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What factors are affected with the PT is normal and the PTT is elevated?
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Factors VIII, IX, XI, XII, or von Willebrand's
Intrinsic pathway |
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What enhances antithrombin?
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Presence of heparin
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What breaks the fibrinogen and the fibrin monomers?
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Plasmin
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Indirect Antibody/Coombs looks at maternal serum to detect what disease?
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Hemolytic Disease of Newborn
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Which test for DIC would NOT be increased in liver disease?
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D-Dimer
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What 5 tests should you order for suspicion of DIC?
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Platelet count
PT PTT Fibrinogen D-Dimer |
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What is protein S in relation to protein C?
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Protein S is the cofactor for Protein C
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What is the role of fibrinolysis?
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Dissolves unwanted clots
Restores blood flow Keeps coagulation in check |
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What does the Indirect Antiglobulin Test look for?
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Antibodies that are not supposed to be there in the serum
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Which pathways does the PTT measure?
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intrinsic & common
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ABO antibodies are which Ig?
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IgM, cold reacting
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Microspherocytes are seen in which HDN, Rh or ABO?
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ABO
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Which blood type is the universal recipient?
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AB
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When can an abbreviated crossmatch be done?
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When the antibody screen is negative
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What prevents HDN?
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Ante- and post-natal Rho-Gam
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What is a normal PT time?
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11-13 seconds
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What pathway does a thrombin time test measure?
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Final steps of common pathway
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Which blood type is the universal donor?
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O
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When is the DAT positive?
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Autoimmune Hemolytic Anemia
Hemolytic disease of the newborn Hemolytic transfusion reactions Drug therapy |
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When is Rho-Gam started?
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28 weeks of pregnancy and at delivery
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What does type & screen mean?
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ABO
Rh Antibody screen |
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Which test is the routine test for fibrinolysis?
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D-Dimer
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Which tests are decreased in DIC?
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Platelet count
Fibrinogen |
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What does a crossmatch look at?
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Donor RBCs, recipient serum to determine compatibility
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What are the two ways to get exposed to Rh antibody?
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Pregnancy
Transfusion |
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What is a normal PTT time?
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28-40 seconds
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What is Rho-Gam?
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anti-Rh IgG
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PT is exclusive for which factor?
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Factor VII
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Which test is increased in DIC?
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D-Dimer
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What level should bilirubin not be above without a transfusion?
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20.0
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What would you suspect in a patient with a bleeding problem who has normal PT & PTT?
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platelet deficiency, vascular defect, or factor XIII deficiency
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