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187 Cards in this Set

  • Front
  • Back
The skin synthesizes what vitamin?
Vitamin D
Which layer of the skin does not have blood vessels?
Epidermis
Where are the sebaceous glands located?
Dermis
What are the four pigments of the skin?
Melanin
Carotene
Oxyhemoglobin
Deoxyhemoglobin
What is poor skin turgor?
An abnormality in the skin's ability to change shape and return to normal (elasticity)
What is poor skin turgor commonly a sign of?
Dehydration
What areas of the skin are associated with atopic dermatitis?
Back of knee & antecubital areas (flexor surfaces)
What areas of the skin are associated with psoriasis?
Knees & elbows
(Extensor surfaces)
Where does pityriasis rosea usually occur?
Trunk
What is the size of a macule?
Less than 0.5 cm in diameter
Freckles and petechiae are examples of what kind of skin lesion?
Macule
Macules are what?
Small, flat spot
Any color
What size is the diameter of a papule?
Less than 0.5 cm
Papules are what?
Small palpable lesion
Any color
Surface can be smooth or rough
What is a nodule?
Enlargement of a papule in length, width, and height
What is a patch?
Extension of a macule in length and width
What size is a patch?
0.5 cm or larger in diameter
What is a plaque?
Enlargement of a papule in length and width
What is a pustule filled with?
Neutrophils
What is the size of a vesicle?
Less than 0.5 cm in diameter
A vesicle can be thought of as what?
A fluid filled papule
A bulla is very similar to what other lesion?
Vesicle
What is the size of a bulla?
0.5 cm or larger in diameter
What is crust, and what is an example?
Dried residue of serum, pus, or blood
Example - impetigo
What is a scale?
A thin flake of exfoliated epidermis
What are some examples of a scale?
Dandruff
Dry skin
psoriasis
What is an example of a target lesion?
Erythema multiforme
Herpes Zoster follows what type of pattern?
Dermatomal
Unilateral
Herpes Zoster - Shingles has what kind of lesions?
Vesicular
A patient with shingles will feel what prior to eruption?
Prickly, tingly sensation
What skin condition has a herald patch that precedes the full eruption by 1-2 weeks?
Pityriasis Rosea
Pityriasis rosea follows what type of pattern?
Christmas tree
Describe the eruption of pityriasis rosea.
Oval
fawn colored
scaly
Mildly puritic
Confined to trunk
What type of disease is pityriasis rosea?
Common, mild, acute inflammatory
What are the treatments for pityriasis rosea?
Antihistamines
Topical steroids
Oral erythromycin
How long does pityriasis rosea usually last?
6 weeks
What causes molluscum contagiosum?
Poxvirus
What does the rash of molluscum contagiosum look like?
Single/multiple rounded, dome-shaped, waxy papules
2-5 mm, umbilicated
How is molluscum contagiosum spread?
Wet skin to skin contact
When molluscum contagiosum is located in the genital region, what is it considered?
STD
What is the treatment for molluscum contagiosum?
Curettage or liquid nitrogen
What does HSV look like?
Grouped vesicles on an erythematous base
What are the symptoms of HSV?
Burning, stinging
Neuralgia
Regional adenopathy
What tests are positive in HSV?
Tzanck smear
Viral cultures
Serologies
ELISA
Direct fluorescent antibody tests
What are the treatments for HSV?
Systemic agents (acyclovir, famciclovir, valacyclovir)
Topical agents
Pyoderma is a complication of what virus?
HSV
What is the drug of choice for shingles?
Acyclovir
Can also use valacyclovir or famciclovir
When is shingles considered an emergency?
When it involves the facial nerve - can see lesion on tip of nose
What are verrucae more commonly known as?
Warts
What are verrucae caused by?
HPV
How long is the incubation period for verrucae?
2-18 months
Imiquimod treats what skin condition?
Verrucae (warts)
Podophyllum resin treats what skin condition?
Verrucae (warts)
Bleomycin treats what skin condition?
Verrucae (warts)
What is cellulitis?
A bacterial infection of the dermis and subcutaneous tissues
What are the symptoms of cellulitis?
Warmth
Erythema
Edema
Tenderness
Later: Fever, chills, malaise
How long is the onset to presentation of cellulitis?
6-36 hours
What skin condition is ascending lymphangitis associated with, and what does it look like?
Cellulitis
Red streaking
Cellulitis with a violaceous collor and bullae suggests infection with what?
Strep pneumoniae
Cellulitis of the lower extremities can develop into what (especially in geriatric patients)?
Thrombophlebitis
What antibiotics could you use to treat MSSA cellulitis in an inpatient?
Cefuroxime
Ceftriaxone
Dicloxacillin
With MRSA cellulitis, what drugs could be used?
TMP/SMZ
Clindamycin
What is scalded skin syndrome?
Acute exfoliation of the skin following an erythematous cellulitis
What is scalded skin syndrome caused by?
An exotoxin from a staph infection
Scalded skin syndrome is most common in what populations?
Children
Neonates
Mortality rate in scalded skin syndrome is highest in what population?
Adults (20-30%)
Describe the rash of scalded skin syndrome.
Diffuse erythematous rash
Tender, warm
Exfoliation
Perioral crusting
Facial edema
Sandpaper like rash, accentuated in flexor creases
What is the treatment for scalded skin syndrome?
IV fluids - lactated Ringer solution
Topical wound care similar to burns
Topical antibiotic ointment
Parenteral antibiotics to cover S. aureus
What drugs should be avoided in the treatment of scalded skin syndrome?
Steroids
What is the name of the superficial bacterial skin infection that extends into the cutaneous lymphatics?
Erysipelas
Where does erysipelas usually occur?
on the face
What bacteria usually causes erysipelas?
Strep pyogenes
Erysipelas is sharply demarcated, true or false?
True
What tests are useful in diagnosing erysipelas?
CBC w/diff
ESR
Urinalysis
Cultures
What are the first-line agents for treating erysipelas?
Pen VK
Pen G
What drug should be used in PCN allergic patients to treat erysipelas?
Erythromycin
What is the most common skin infection in children?
Impetigo contagiosa
What causes impetigo?
group A beta-hemolytic strep OR staph aureus
What is the most common location for impetigo?
Face - around mouth and nose
Also could be around a site of trauma
What color are the crusts in impetigo?
Honey-colored
What is usually used to treat MSSA impetigo?
Keflex
What is used to treat recurrent impetigo?
Rifampin
or intranasal mupirocin
What are furuncles caused by?
Staph entering damaged hair follicle
Where are furuncles most commonly found?
Face
Neck
Armpit
Buttocks
Thighs
What does an early furuncle look like?
Small firm tender red nodule
In the late stages of a furuncle, what may happen?
Pus-filled
Inflammation
Tenderness
Mobility
What is the treatment for furuncles?
Usually heal on their own, must drain
Can use warm moist compresses
Need good hygiene
What is folliculitis?
Inflammation of hair follicules as a result of obstruction/disruption
What is the treatment for folliculitis?
Topical & oral antibiotics
Wash with antibacterial soaps
What bacteria usually causes hot tub folliculitis?
Pseudomonas
Gram negative folliculitis in acne patients can be treated with what?
Isotretinoin
Eosinophilic folliculitis can be treated with what?
Topical corticosteroids
Oral antihistamines
What is folliculitis caused by yeast treated with?
topical 2.5% selenium sulfide or oral ketoconazole
What topical antibiotics can be used for acne?
topical EES
topical clindamycin
w/benzoyl peroxide gel
What oral agents can be used for papular inflammatory acne?
Tetracycline
Erythromycin
Oral contraceptives
Spironolactone
What drug can be used for severe cystic acne that is unresponsive to other therapy?
Isotretinoin (Accutane)
What can be used to treat a lesion that needs to be gone overnight?
Intralesional injection of triamcinolone acetonide
Relapse during treatment of acne vulgaris suggests what bacteria?
Resistant propionibacterium acnes
What is the most common mycotic infection?
Candidiasis
Which Candida is most commonly responsible for candidiasis?
Candida albicans
What is the medical term for ringworm?
Tinea corporis
Tinea cruris is more commonly known as what?
Jock itch
Tinea versicolor usually flares up in what season?
Summer
What is the most common cause of mouth sores in children?
Hand/foot/mouth
What causes hand, foot, & mouth disease?
Coxsackie virus
What illness in children presents with copious drooling?
Hand, foot, & mouth disease
What are the ingredients in "magic mouthwash"?
Mylanta
Benadryl
Xylocaine
What is pediculosis?
Infestation with lice
What is pubic lice known as?
Pthirus pubis
What is the body louse a vector of?
Typhus
Trench fever
Relapsing fever
What is the "home remedy" for removal of lice?
Water & white vinegar
Soak hair in solution & wrap in towel for 15 minutes
What can eyelash infestation of lice be treated with?
Petrolatum ointment (Vaseline)
What is the DOC for lice?
Permethrin 5% (Elimite) or 1% (Nix)
What lice treatment is not very safe in children?
Lindane 1% shampoo (Kwell)
What causes the pruritus associated with scabies?
The feces of the parasite
What are the treatments for scabies?
Lindane
Permethrin cream
Crotamiton (Eurax)
What insect bite presents with an erythematous halo around the lesion?
Brown recluse spider
When does the hemorrhagic vesicle appear in a brown recluse bite?
24-72 hours after the bite
Which insect bite presents with an eschar in its later stages?
Brown recluse spider
What toxin causes the effects of a brown widow spider bite?
Alpha-Iatrotoxin
How does alpha-iatrotoxin from a black widow bite cause toxic effects?
Opens cation channels (including calcium channels) presynaptically, causing increased release of multiple neurotransmitters
What are the most common effects of a black widow bite?
Neurologic
Autonomic
What will the vital signs show in a patient bitten by a black widow spider?
Hypertension
Tachycardia
What are the treatments for an uncomplicated black widow spider bite?
Pain control
Benzodiazepines
Immunizations (Tetanus)
Antivenom
For a patient showing serious effects of a black widow bite, what should be done?
Admit to hospital; urinalysis; evaluate for evidence of coagulopathy, hemolysis, hemoglobinuria, renal failure, further progression
Rosacea is most common in what population?
White women between 30-60
Severe rosacea in men can cause what?
Rhinophyma
(Red, enlarged nose)
What are the treatments for rosacea?
Avoid aggravating situations
Antibiotics (tetracycline)
Accutane
Gels/Creams
What are the treatments for perioral dermatitis?
Anti-inflammatories
Metronidazole
Doxycycline/Minocycline
What disease presents with swollen, painful, inflamed lesions in the axillae and groin?
Hidradenitis suppurativa
Hidradenitis suppurativa occurs as a result of what?
Apocrine gland outlets become blocked by perspiration or cannot drain normally because of incomplete gland development
What other diseases does hidradenitis suppurativa resemble?
Recurrent bacterial folliculitis, furunculosis
Down syndrome, Hashimoto thyroiditis, Sjogren's syndrome, Crohn's, IBS, and Herpes simplex are associated with the presence of what skin condition?
Hidradenitis suppurativa
What are the antibiotics used in the treatment of hidradenitis suppurativa?
Tetracycline
Erythromycin
Acute: Cephalosporins
What is a biopsy in which a sample of the suspicious tissue is cut into?
Incisional
What is the primary technique for obtaining diagnostic full skin thickness samples?
Punch biopsy
What are the two types of incisional biopsies?
Punch
Shave
What is a procedure that completely removes a lump or abnormal area from the skin?
Excisonal
What does an excisional biospy look for?
Cancer
Infection
Inflammation
What procedure offers the highest potential from recovery of skin cancer?
Mohs Micrographic Surgery
What two cancers are commonly treated with Mohs?
Basal cell
Squamous cell
What skin condition is associated with tapioca vesicles on the palms, soles, and sides of fingers?
Dyshidrosis
What controlls the process of sweating?
Sympathetic Nervous System
Two thirds of the body's sweat glands are located where?
Hands
Tannic acid, aluminum hexahydrate, formalin, and glutaraldehyde are examples of what?
Prescription antiperspirants
Tranquilizers, anticholinergics, NSAIDs, Calcium channel blockers, Catapres are examples of what?
Oral antiperspirants
Milaria crystallina is most common in what climates?
Hot, humid
What condition occurs in a minority of those who have repeated bouts of miliaria rubra?
Miliaria profunda
What vaccination should not be given to individuals or family members of those with atopic dermatitis?
Smallpox
What physiologic process causes urticaria?
Release of histamine, bradykinin, kallikrein, or acetylcholine, resulting in intradermal edema and occasional leukocyte infiltration
Which immunoglobulin is associated with urticaria?
IgE
What is the first line treatment for urticaria?
Antihistamines
usually Hydroxyzine or diphenhydramine
When are glucocorticoids indicated for urticaria?
Serious and refractory cases
Which dermatitis affects only those previously sensitized to an irritant?
Allergic contact dermatitis
What type of hypersensitivity reaction is allergic contact dermatitis?
Cell mediated type IV
What are the most common allergens causing allergic contact dermatitis?
Toxicodendron genus
Poison ivy, oak, sumac
Which dermatitis is associated with immunological abnormalities?
Seborrheic dermatitis
Nummular eczema takes what shape?
Coin shaped
Where is nummular eczema most commonly found?
Arms & legs
Nummular eczema starts as what and progresses to what?
Starts as papules, coalesces into plaques
What climate typically aggravates nummular eczema?
Cold or dry
What is the most common form of alopecia?
Androgenic (pattern) baldness
What are the drugs used for pattern baldness?
Rogaine
Propecia (only in males)
For what form of alopecia is the pull test performed?
Alopecia areata
What systemic drugs are used to treat alopecia?
Corticosteroids
What illness is described as a transitory increase in the number of hairs in the telogen phase of the hair growth cycle?
Telogen effluvium
When does telogen effluvium usually occur?
After pregnancy
Crash dieting
High fever
Stress
Shock
Surgery
What illness is a loss of functional melanocytes?
Vitiligo
What is the most effective treatment for vitiligo?
Systemic phototherapy (70% success)
What is melasma?
An acquired hypermelanosis of sun-exposed areas
What does melasma present as?
Symmetric hyperpigmented macules
What are the most common locations for melasma?
Cheeks
Upper lip
Chin
Forehead
What is the name for melasma during pregnancy?
Chloasma
What must be avoided in the treatment of melasma?
Sunlight
Koebner's phenomenon is associated with what disease?
Psoriasis
Silvery scaled plaques on the elbows and knees is suggestive of what disease?
Psoriasis
What is the name for a benign fatty tumor?
Lipoma
What is the medical term for freckle?
Solar lentigo
Blue nevi are common in people of what descent?
Asian
Brown/black benign plaques with a velvety or warty surface are called what?
Seborrheic keratosis
Actinic keratosis can develop into what cancer?
Squamous cell
What are the treatments for actinic keratosis?
Liquid nitrogen OR
5-fluorouracil
What is the most important prognostic factor in malignant melanoma?
Tumor thickness
What may reduce recurrences of malignant melanoma?
Alpha-interferon
Vaccine therapy
What are the most common cutaneous vascular proliferations?
Cherry hemangiomas
Where do dermatofibromas usually develop?
Lower legs
What skin condition is included in the spectrum of fibroproliferative disorders?
Keloids