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20 Cards in this Set
- Front
- Back
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circumventricular organs
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median eminence
vascular organ of lamina terminalis (close to nuclei that regulates blood volume; senses osomotic pressure differences by letting electrolytes into blood to adjust vasopressin) median eminence; important for feeding and metabolism neurohypophysis; releases hormones from hypothalamus |
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anterior vs posterior pituitary
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posterior; neurons stimulate neurohypophysis
anterior; nerves release hormones into first part of hypophyseal portal system; |
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only nerve IN the cavernous sinus
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VI; all others are in the lateral bone (III, IV, V1, V3
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where does blood in the cavernous sinus go?
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jugular -> anything that goes into cavernous sinus (i.e. hormones) ends up in the venous circulation
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lateral nucleus
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hunger center; destruction -> anorexia, failure to thrive (infants)
inhibited by leptin |
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which area does leptin inhibit
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lateral area
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no leptin present
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no latereal nucleuar inhibition -> constant hunger/obesity
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ventromedial nucleis
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satiety area; Desturction (craniopharyngioma) -> hyperphagia; stimulated by leptin
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which nucleus does leptin stimulate
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ventromedial area
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leptin deficiency
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make you fat
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MCR4 gene deficiency
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receptor for melanocortin; more common than leptin deficiency
results in obesity |
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melanocortin
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leptin gains entrance through median eminance; 2 receptors for leptin on neurons in arcuate nucleus
POMC/CART receptor (stimulated by leptin) NPY/AgRP receptor (inhibited by leptin) leptin decreases feeding |
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POMC/CART
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Leptin stimulates these neurons which inhibits hunger
decreased hunger |
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NPY/AgRP
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Leptin inhibits these which stimulate hunger
decreased hunger |
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POMC
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pro-opio-melanocortin
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suprachiastmatic nucleus
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circadian rhythm
you need sleep to be charismatic (chiasmatic) |
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SCN clock machinery
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Clock/BMAL, cryptochrome/period = heterodimers that regulate eachother and make up the SCN clock machinery
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intermediate lobe
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anterior pituitary
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posterior pituitary
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