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25 Cards in this Set

  • Front
  • Back

H


S


D


R


E


C


B&c


L


R


u


C N

List the order of the systems response to radiation exposure from most sensitive to least sensitive..

Acute radiation syndrome

Sickness that occurs in humans after large whole body dose of radiation received in a short time.

Prodromal

First stage, happens after hour of 1 gray or more.



Nausea, committing,



Leukopenia

200-300 rad

Sub lethal , recovery in 3 months

Super lethal

No recovery after 600-1000 rad

Death in 3-10 days. Infection, Hermitage, dehydration

Gastrointestinal syndrome death in how many days after damage to skin and intestine cells?

3-4 Gy . 6 gy death in all. 8.5 recovery with medz

LD 50/30

LD,

Measure how lethal a dose is

90% repair over time

Damage from radiation

Carcinogenesis. And embryological effects.

Stochastic late effects are

Deterministic effects. Non-Linear threshold

Cataractogenesis and nonspecific life span shortening.

700 rads

Cataracts

500-600 rads,

Permanent sterility

25 rads

Decrease in stem cells and lymphocytes

Late effects from subelthal dose

Seen in 10 years. Recovery is 3 months

Cataractogenesis

High probability from 200 rad dose

Life span shortening

Loss of parachymal cells, organ atrophy, fibrosis

Teratogenesis

Birth defects caused by radiation exposure of fetus

20 rad, organogenesis

Fetal abnormalities

Preinplanation

5-15 rad caused embryological death

Fetal stage 6 weeks to term

Skeletal damage. Childhood cancer, sterility

3x rate of deformities and abnormalities. Miscarriages, still birth. Premature birth

Children exposed in ureto at Chernobyl

Spontaneous late genetic effects

Sickle cell anemia. Down syndrome

Mutagens

Increase frequency of mutations

Measures effectiveness of causing mutations . 156 rem in humans is amount of radiation that causes 2x mutations

Doubling dose concept