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14 Cards in this Set

  • Front
  • Back

growth hormone excess is associated with what

adenomas of the pituitary gland

prolonged exposure to GH excess causes what

overgrowth of the skeleton and soft tissue (acromegaly)

what is pituitary gigantism

GH excess is seen before long bone growth is complete

where is pituitary gigantism evident

face and extremities

pituitary gigantism causes what

striking acceleration of linear growth

children who have inadequate GH production or a GH receptor defect do not what

grow normally

GH deficiency is caused by what 3 things

- congenital or acquired


- damage to the pituitary gland or hypothalamus


- deficiencies of other pituitary hormones

what is psychosocial dwarfism

reversible GH deficiency state that leads to GH suppression and growth retardation

what causes psychosocial dwarfism

environmental stress

what percent of children with growth retardation have endocrine problems

15%

what portion of the 15% of children with growth retardation have GH deficiency

½

GH deficiency in adults is the most common demonstrable abnormality in patients with what 2 things

large pituitary adenomas


pituitary irradiation

GH deficiency in adults leads to what 5 things

premature mortality


abnormal body composition


impaired serum lipids


decreased bone density


overall impaired quality of life

how is GH deficiency treated

GH replacement therapy