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16 Cards in this Set
- Front
- Back
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Pt with severe epigastric pain after fatty meal; history of this same occurence; tenderness in right subcostal area; which hormone likely provoked this attack?
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CCK; biliary colic (gall bladder disease = 4 Fs); produced by I cells in duodenum and jejunum when fat protein rich chyme enters the duodenum; increases pancreatic enzyme secretion and gall bladder contraction as well as decrease stomach emptying
in cholecystitis, fatty foods increase CCK production and pain occurs when an inflammed or obstructed gallbladder contracts |
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Women with cholecystectomy eats mealw ith triglycerides; where in the GI tract are the dietary lipids absorbed?
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Jejunum; emulsified by bile, turned into micelles brings them to the brush border; absorbed into lacteals
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Pt with total gastrectomy after gastric cancer; what should he receive supplementation of
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B12 administration, since parietal cells in the stomach normally produce itnrinsic factor; even though pepsin is in the stomach proteins can still be digested after total gastrectomy
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Pt with nighttime abdominal pain relieved by food. No significant PMI and takes no meds. Endoscopy reveals pep ulcer in proximal duodenum. What medication wold provide long term relief?
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Antibiotics; kills H. pyloi
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Ranitidine
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H2 blocker
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Sucralfate
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Binds to base of mucosal ulcers, protects against gastric acid. Helps ulcers heal but not effective at preventing reccurence
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Metoclopramide
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Dopamine antagonist; prokinetic (speeds food through GI tract), antiemetic
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Misoprostol
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Prostagladin E1 analog; prevent NSAID induced ulcer disease
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A drug that decreases HCl output in response to vagal, histamine and gastrin stimulation is what
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Omeprazole, Lansoprazole -> PPI blocks the final common pathway of gastric acid secretion from parietal cells
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Diphenoxylate
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Opiate antidiarrheal; binds to mu opiate receptors in the GI tract and slows motility.
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2 vaccines: one live, one killed; the levels of which antibodies will difer the msot betweeum the two recipients?
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Duodenal IgA; live attenuated vaccine when applied to mucosal surfaces prolongs the synthesis and secretion of local mucosal IgA than does a killed vaccine. Offers immune protection at the normal site of viral entry.
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1 yo with recurrent, indolent skin infections and gingivitis. PMH significant for delayed umbilical cord separation. What protein is likely underexpressed in this pt?
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Integrins; LAD results from autosomal recessive genetic absence of CD18; leads to inability to synthesize integrins; integrins are necesary for leukocytes toe xit the bloodstream and se1uelae of this ilness include reccurent infections WITHOUT pus formation,d elayed detachment of the umbilical cord and poor wound healing.
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Pt w schistosomiasis; high blood eonsinophil count; how does eosinophils contribute to host defense?
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Antibody dependent cytotoxicity; Eosinophils play a role during parasitic infection, when stimulated by IgE bound to a parasitic cell they destroy the parasite via antibody dependent cellular cytotoxicity with enzymes from their cytioplasmic granules (major basic protein); eosinophils also regulate type I hypersensitivity reactions
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Mutation of FAS protein would do what
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FAS mutation prevents apoptosis of autoreactive lymphocytes, thereby disposing individuals to develop autoimmune disorders like SLE
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Describe how the immune system regulates candida albicans
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Localized defense: T cells
Systemic defense: Neutrophils HIV pts likely have localized candidiasis while neutropenic individuals more likely to have systemic disease |
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B cell surface markers
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CD19,20,21
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