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6 Cards in this Set

  • Front
  • Back
-This hormone is an anabolic hormone
-Promotes protein synthesis and mobilizes glucose and fatty acids
-Produced by the anterior pituitary and stimulates the liver to produce insulin-like growth factor-1
-Stimulates the growth of bones and soft tissues
-Growth Hormone
What does overproduction of growth hormone cause?
-leads to unwanted growth of bones and other soft tissue
-causes elevation of BG leading to glucose intolerance
-In children: results in giantism
-In adults: results in acromegaly (overgrowth of bones and soft tissues); however, bones are unable to grow long so they grow in width and thickness
What causes overproduction of growth hormones?
-almost always caused by benign pituitary tumor (adenoma)
Describe s&s of an overproduction of growth hormones:
-begin gradually (20-30s)
-enlargement of hands and feet
-club-like fingers
-range from mild joint pain to deforming, crippling arthritis
-thickening and enlargement of bony and soft tissues on the face and head
-jaw juts forward
-paranasal and frontal sinuses enlarge
-forehead enlarges
-coarsening of facial features
-tongue enlarges
-voice deepens
-sleep apnea
-skin becomes thick, leathery, and oily
-peripheral neuropathy
-proximal muscle weakness
-colon polyps and poss cancer
-visual disturbances and headaches
-predisposes to atherosclerosis
-hyperglycemia (polydipsia and polyuria)
-cardiomegaly, left ventricular hypertrophy, angina pectoris, and HTN
Most frequently-occurring pituitary tumor:
-Prolactinomas
A rare disorder that involves a decrease in one or more of the pituitary hormones:
-hypopituitarism