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62 Cards in this Set

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Where is the pancreas located?
Behind the stomach
A&P of the Pancreas
*Lies behind the stomach
*Has endocrine & exocrine functions
*Islets of Langerhans perform endocrine functions
*Alpha cells secrete glucagon
*Beta cells secrete insulin
Major stimulus for insulin secretion
Carbohydrates
The pancreas has _______cells & _________cells.
Alpha cells & Beta cells
Alpha cells
Responsible for creating glucagon
Beta cells
Create insulin
Glucose homeostasis
Gluconeogenesis
Glycogenolysis
Glucagon
Hormone released to increase blood glucose levels
Insulin
Lowers blood glucose levels
Increase after a meal
Inhibits gluconeogenesis
High blood sugar >>>Pancreas>>>Insulin>>>Tissue cells>>>Lowers Blood Sugar
Low blood
sugar>>>Pancreas>>>Glucagon>>>Liver>>>Raises Blood Sugar
Diabetes patients are more at risk to develop what disease?
Cardiovascular disease
Diabetes patients are also at risk for ____________.
infection
What is Diabetes Mellitus?
A disturbance in CHO, protein, and lipid metabolism because of a deficiency of insulin, marked by hyperglycemia.
Diabetes Mellitus is a multisystem disease related to:
*Abnormal insulin production
*Impaired insulin utilization
*both abnormal production and impaired utilization
What is the leading cause of heart disease, stroke, adult blindness, and non-traumatic lower limb amputations?
Diabetes Mellitus
Why is the patient not getting enough insulin?
1. The pancreas isn't producing enough insulin.
2. Insulin is being released by the pancreas, but it isn't being utilized by the body.
3. A combination of both 1 & 2.
What happens between meals?
Blood glucose low>>pancreas secretes glucagon>>liver changes glycogen to glucose>>Glucose sent to target tissues.
What happens after a meal?
Blood glucose high>>pancreas secretes insulin>>glucose goes to the liver (Glygogen) & goes to target tissues
Diabetes Mellitus Classification
*Type 1 Diabetes
*Type 2 Diabetes
*Metabolic Syndrome (Syndrome X)
*Gestational Diabetes Mellitus
Which type of Diabetes is insulin dependent?
Type 1
Which type of Diabetes is non-insulin dependent?
Type 2
Which type of diabetes is "Insulin resistant"?
Metabolic Syndrome (Syndrome X)
What type of diabetes would you see in pregnant women?
Gestational diabetes mellitus
Gestational diabetes mellitus
Develops during pregnancy. Normally goes away after the baby is born. Increases your risk for developing diabetes later in life by 80%
Who is more at risk to develop Type 1 Diabetes?
White females with a lean body type
Type 1 Diabetes
Autoimmune disorder - beta cell destruction in the pancreas occurs in a genetically susceptible individual.
Without insulin, glucose builds up causing hyperglycemia.
Causes fluid and electrolyte imbalances.
Most often occurs in people under 30 yrs old.
Peak onset between ages 11 & 13.
Clinical Manifestations of Type 1 Diabetes
Develop when the pancreas can no longer produce insulin
*weight loss
*polyuria
*polydipsia
*polyphagia
*weakness & fatigue
*Diabetic Ketoacididosis (DKA)
*Kussmaul's respirations
Polyuria
Frequent urination
Polydipsia
Excessive thirst
Polyphagia
Excessive hunger
What type of diabetes is preventable?
Type 2 Diabetes
Which type of diabetes accounts for 90% of patients with DM?
Type 2 diabetes
Type 2 Diabetes
*Accounts for 90% of patients with DM
*Usually occurs in people over 40 years of age.
*80-90% of patients are overweight
*Etiology & Pathophysiology
Pancreas continues to produce some endogenous insulin
*Onset of disease is GRADUAL
Type 2 Diabetes
Major Risk Factors
*Family history
*Obesity > or = 20% above ideal
*Race:Native American, Hispanic, African American
*Age >40 yrs old
*Impaired glucose tolerance
*Hypertension, hyperlipidemia
*Gestational diabetes, babies>9 pounds
Diagnostic Studies for DM
*Fasting blood glucose
*Oral glucose tolerance test
*Glycosylated hemoglobin-hemoglobin A1c
*Urine ketones
*Urine glucose
*Self-monitoring of blood glucose
Fasting blood glucose
NPO for 8 hours.
Should be less than 100.
If you test >126 on 2 different occasions you will be diagnosed with diabetes
Oral glucose tolerance test
Drink a sugary drink & get tested 1 hr later, 2 hrs later, 3 hours later, ect.
Sometimes used to test for gestational diabetes.
Glycosylated hemoglobin
Blood test to see where sugars have been over a 3 month period. over 6% = diabetic
Urine ketones
Ketones could be an indicator to evaluate further
Urine glucose
Sugar is greater than 300 if in the urine
How often should a type 1 diabetic check their glucose?
4 times a day.
How often should a type 2 diabetic check their glucose?
one time a day unless they don't feel well
Type 1 Diabetes Treatment Options
1. Insulin
2. Nutrition and diet
3. Exercise
You should teach your diabetic patient to exercise how often?
30 minutes, 5 times a week
Which type of Insulin can be given IV?
Regular
Rapid Insulin
Humalog
(Lispro)
Novolog
Apidra
Short Insulin
Regular
Intermediate Insulin
NPH
Long Acting Insulin
Lantus
Levemir
Typically give once per day. Usually given at bedtime.
Mixed Insulin
Regular & NPH
70/30
75/25
50/50
Where do you give insulin injections?
#1 site Abdomen, #2 site Arm, #3 site Thigh. Avoid rubbing. Rotate sites (1 1/2 inches apart)
Subcutaneous injections
Name the different ways you can administer insulin
Syringes -most common 100 unit. Insulin pen - you don't have to keep it in the fridge. Good for people who work. Insulin pump - used by very compliant & intelligent patients.
Proper disposal required. Cost varies.
What is the most important thing a diabetic can do?
Carb counting
What is the total carbohydrate goal/meal For diabetics
45-60g/meal
Foods containing carbohydrates
Starches (bread, cereal, pasta, rice, grains, potatoes, beans, corn). Fruits & fruit juices. Milk & yogurt. Sweets, desserts, beverages
Approx ______g___carbs/snack
15g
How many snacks per day can a diabetic have?
2 snacks per day. Approx 15g carb/snack
What do you teach your diabetic patient about food choices?
Drink skim or 1% milk instead of whole milk. Avoid sweet tea & coke. Eat an apple or and orange instead of drinking the juice.
If ____or more grams of fiber in serving, may subtract grams of fiber from total carbohydrate count per serving
5. Ex: 60 total carbs, 7 g of fibers = 53g of total carbs
Carbs turn to ___________, sugar turns to __________.
Carbs turn to sugar, sugar turns to Fat.
Long acting insulin
Lantus. Onset 2-4 hrs, no peak time, duration 24 hrs
Type diabetic medication