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9 Cards in this Set
- Front
- Back
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immune privilege in testis
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tight junctions between sertoli cells protect testis
sertoli cells secrete TGF-B and FasL to blow up lymphocytes testis macrophages secrete Il-10 (antinflammatory) androgens/steroids produced by testis suppress immune activity can still get immune response with trauma/orchitis |
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antisperm antibodies
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they exist; only a couple specific kinds can cause infertility, but w in vitro fertilization not much research is done on them anymore
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which dz is premature ovarian failure associated with
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Addisons dz
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APS2 (thyroid dz + addisons dz)
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potential cause of gonadal failure in females
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APS1 (AIRE defect = no tolerance = autoimmune)
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potential cause of gonadal failure in females (ass with mucocutaneous candidiasis, hypoparathyroidism, addisons dz)
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mucocutaneous candidiasis, hypoparatyroidism, addisons disease
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APS1, ass w gonadal failure in men
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thyroid disease + addisons disease
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APS2
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why are men infertility in CF in men?
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plugged vas deferans, 95% of men are infertile
normal spermatogenesis normally |
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Kartageners syndrome
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immotile cilia due toa dyenin arm defect; male/femaele infertility (sperm immotile), bronchiectasis (respiratory tract lined w cilia), recurrent sinusitis (bacteria/particles not pushed out)
associated w situs inversus |
