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10 Cards in this Set

  • Front
  • Back
What are pathogens?
Pathogens are microorganisms that cause disease. for a microorganism to be considered a pathogen it must:
- gain entry to the host
- colonise the tissue of the host
- resist the defences of the host
- cause damage to the host tissue
How do pathogens enter the body?
By penetrating one of the organism's interfaces with the environment:
- the gas exchange system (e.g. influenza, tuberculosis).
- the digestive system (e.g. cholera, typhoid).
To prevent the entry body has a number of natural defences:
- a mucus layer forms a thick, sticky barrier
- enzymes, which break down the pathogens
- stomach acid, which kills microorganisms
How do pathogens cause disease?
Pathogens affect the body in two ways:
- by damaging the host tissues. Viruses inhibit the synthesis of DNA, RNA and proteins by the host cells and many pathogens break down the membranes of the host cells.
- by producing toxins. most bacterial pathogens produce toxins e.g. cholera bacterium produces a toxin that leads to excessive water loss from the lining of the intestines.
How are data on disease interpreted and analysed?
Epidemiologists collect data on diseases and the look for a pattern or a relationship between these diseases and various factors in the lives of people who have them.
What is a correlation and what does it mean?
A correlation occurs when a change in one of two variables is reflected by a change in the other variable.
A correlation does not mean that there is a causal link!
How is a causal link established?
A causal link is established when we can provide experimental evidence of which specific factor and how affects the formation of disease.
What is a risk?
A risk is a measure of the probability that damage to health will occur as a result of a given hazard.
Risk has two elements:
- the probability that hazardous event will occur
- the consequences of that hazardous event
How is a risk measured?
It can be measured as a value that ranges from 0 per cent (no harm will occur) to 100 per cent (harm will certainly occur).
Health risks need a timescale and it is often relative- comparing the likelihood of harm occurring in those exposed to hazard with those who are not exposed to it.
What factors affects a risk of contracting cancer?
- Smoking; also those who passively breathe tobacco smoke also have an increased risk of getting cancer.
- Diet; strong evidence that a low-fat, high-fibre diet, rich in fruit and vegetables reduces the risk.
- Obesity
- Physical Activity; people who take regular exercise are at lower risk from some cancers.
- Sunlight; the more explosion to sunlight or light from sunbeds the greater the risk of skin cancer.
What factors affect a risk of contracting a coronary heart disease?
- Smoking
- High Blood Pressure
- Blood Cholesterol Levels
- Obesity
- Diet; high levels of salt in diet raise the blood pressure while high levels of saturated fatty acids increase blood cholesterol concentration.
- Physical Activity