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16 Cards in this Set
- Front
- Back
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How can you give UFH
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SQ, IV
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Bioavailability of UFH
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30% because binding with plasma proteins
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What is the half life on UFH
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dose dependent, between 30 and 150 mins
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How can UFH be dosed
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Raschke nomogram (weight-based) and standard nomogram
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how do you monitor UFH
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aPTT (therapeutic is 1.5-2.5)
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(UFH indications) acute coronary syndrome
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full dose IV hep protocol
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(UFH indications) thromboembolic event
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full dose IV hep protocol
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(UFH indications) a fib
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full dose iv hep protocol
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(UFH indications) acute cerebrovascular accident
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low-lose or full dose iv hep protocol
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(UFH indications) DVT prophylaxis
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hep 5000 units sq 8-12 hrs
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UFH adverse effects
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bleeding, injection site irritation, hematoma, thrombocytopenia, hyperkalemia
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UFH reversal
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protamine sulfate (forms a complex with UFH to neutralize activity)
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Onset of activity for protamine sulfate
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within 5 mins
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How is protamine sulfate given
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iv
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How is protamine sulfate diagnosed
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1 mg/100 units of hep
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Why do you need a hep drip
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because its halflife is dose dependent
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