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35 Cards in this Set
- Front
- Back
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What is the Brand name of Atropine?
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Atro-Pen
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How is Atropine typically supplied (concentration)?
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0.4 mg/ml OR 1 mg/ml
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The usual dose of Atropine is?
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0.01 - 0.02 mg/kg OR 0.5-1 mg
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What is the time to onset of Atropine?
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1 minute
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What is the time to peak of Atropine?
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2 minutes
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What is the duration of Atropine?
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1-4 hrs
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How is Atropine metabolized?
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50-75% liver
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What receptors does Atropine act on?
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Muscarinic blocker
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What drug class is Atropine in?
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Anticholinergic
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What is the mechanism of action of Atropine?
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competitively blocks binding of acetylcholine and prevents receptor activation
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What patients would you not give Atropine to?
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caution in narrow angle glaucoma, prostatic hypertrophy, bladder neck onstruction
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Does Atropine cross the blood brain barrier?
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Yes, it is a tertiary ammonium
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What is the Brand name of Scopalomine?
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Hyoscine
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How is Scopalomine typically supplied (concentration)?
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0.3mg/ml, 0.4mg/ml, 1mg/ml
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The usual dose of Scopalomine is?
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0.3-0.6mg IV
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What is the time to onset of Scopalomine?
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10 minutes
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What is the time to peak of Scopalomine?
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50-80 minutes
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What is the duration of Scopalomine?
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2 hours
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How is Scopalomine metabolized?
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hepatic metabolism, renal elimination
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What receptors does Scopalomine act on?
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muscarinic
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What drug class is Scopalomine in?
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anticholinergic, antiemetic
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What is the mechanism of action of Scopalomine?
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peripheral and central cholinergic (muscarinic) antagonist, antisialagogue, histamine and serotonin antagonist
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What patients would you not give Scopalomine to?
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obstetrics- crosses placenta- tertiary amine
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What patients might you give Scopolamine to?
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Unstable trauma patients that are too sick for GA
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What is the Brand name of Glycopyrrolate?
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Robinul
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How is Glycopyrrolate typically supplied (concentration)?
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0.2 mg/ml for injection
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The usual dose of Glycopyrrolate is?
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Premedication 0.1-0.2mg / Reversal 0.2mg per 1mg Neostigmine (1ml/1ml)
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What is the time to onset of Glycopyrrolate?
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<1 min
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What is the time to peak of Glycopyrrolate?
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5 minutes
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What is the duration of Glycopyrrolate?
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2-3 hours
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How is Glycopyrrolate metabolized?
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hepatic
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What receptors does Glycopyrrolate act on?
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muscarinic cholinergic receptors
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What drug class is Glycopyrrolate in?
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anticholinergic
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What is the mechanism of action of Glycopyrrolate?
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reversibly blocks muscarinic cholinergic receptors causing increase HR decreased secreations
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What patients would you not give Glycopyrrolate to?
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Tachycardia, narrow angle glaucoma, prostate hypertrophy, bladder neck obstruction
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