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15 Cards in this Set
- Front
- Back
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Which is not accurate when describing the characteristics of metabolic pathways:
a. they are irreversible (exergonic) b. every one has a first committed step c. catabolic and anabolic pathways differ d. Metabolic pathways are regulated e. Pathways in eukaryotic cells occur in specific cellular compartments f. all of these are true |
f.
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Catabolism: energy-__________
Anabolism: enerty-__________ |
yielding; requiring
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Catabolic pathways converge to ________ end products
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a few
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Anabolic pathways diverge to synthesize _________________
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many biomolecules
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Some metabolic pathways serve both in catabolism and anabolism. These are ___________.
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amphibolic
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Energy-requiring cellular activities are powered by _____________.
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ATP hydrolysis
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Catabolism is ____________ - substrates lose reducing equivalents (e-s), usually H:- ions. ___________ collects electrons released in catabolism.
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oxidative ; NAD+
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Anabolism is ____________. ____________ provides the reducing power (electrons) for anabolic processes
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reductive ; NADPH
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Which end is fully reduced? Fully oxidized?
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left; right
H is least electronegative element, so e-s in that bond are closest to the nucleus of C atom; O is highly electronegative. Fully oxidized C has the LEAST energy. |
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1. Usually the quickest method of influencing an enzymatic activity is by:
A) allosteric regulation. B) covalent modification. C) enzyme induction. D) activation of a zymogen. E) enzyme destruction. |
A
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2. The transition state has an estimated life-time of about:
A) microseconds (10-6 s). B) nanoseconds (10-9 s). C) (10-2 s). D) (10-14 to 10-13 s). E) milliseconds (10-3 s). |
D
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3. The good transition state analog is one which would serve also as an effective:
A) competitive inhibitor. B) noncompetitive inhibitor. C) allosteric inhibitor. D) mixed-noncompetitive inhibitor. E) irreversible inhibitor. |
A
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4. Organic fluorophosphates are ______________ inhibitors of serine proteases such as chymotrypsin, etc.
A) competitive B) uncompetitive C) noncompetitive D) irreversible E) mixed noncompetitive |
D
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5. What’s the circled part of the molecule?
A) niacin B) nicotinamide C) adenine D) ribose E) dinucleotide |
C
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___________________
provides electrostatic stabilization of the carbanion (intermediate) formed by removal of the C-2 proton |
Thiazolium Nitrogen
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