Umkc Dental Pathology 1 2012. Exam 1. Lec. Inflammation

Front 1

Stomatitis=??

Back 1

Inflamation of the MOUTH

Front 2

Mucositis=?/

Back 2

Inflamation of the MUCOSA

Front 3

Periodontitis?

Back 3

Inflamation of the PERIODONTUM =
(PYRA= PUS

Front 4

Lymphadenitis=?

Back 4

Inflamation of the LYMPH NODES = Inflammed lymph gland

Front 5

Tonsilitis

Back 5

Inflamation of the TONSIL
(white parts = pus from crypts)

Front 6

appendicitis
Peritonitis=

Back 6

Appendicitis= Inflamation of the APPENDIX
peroitontitis= Inflamation of the peritoneum
( if pus on appendix= peritontis)

Front 7

Salpingitis=?

Back 7

Inflamation of the FALLOPIAN TUBE

Front 8

Keratitis=?

Back 8

Inflamation of the CORNEA

Front 9

Balanitis=?

Back 9

Inflamation of the GLANS PENIS

Front 10

Cystitis=?

Back 10

Inflamation of the BLADDER

Front 11

Inflammation=?

Back 11

The body's Response to (any type of) Injury--> Thermal, physical, chemical, allergic, or immune-mediated dz

Front 12

Immunity=?

Back 12

Comes into play when INFLAMMATION is caused by a LIVING ORGANISM (infection)
- arises bc inflammation due to some biological agent

Front 13

What are the Body's 3 lines of defense and what does each one include?

Back 13

1. Barriers- Skin, mucous membrane, secretions
2. Inflammatory Response-cells (leukocytes), molecules (Mediators)
3. Immune Response- Antibodies (humoral), Cytotoxic T cells(cellular

Front 14

Bodys 3 lines of defense- barriers, inflamatory response, immune response:
1st line-
2nd line-
3rd line-

Back 14

1st line- NonSpecific- skin, mucous, memrnaeoes, chem.
2nd line-NonSpecific- phagocytosis, complement, interferon, inflammation, fever
3rd line-Specific Defenses- Lymphocytes and antibodies

Front 15

Are inflammation and infection the same thing?

Back 15

NOOOOOO~

Front 16

Infection my provoke:
Inflammation may exist w/o:
___& ____ may cause inflammation

Back 16

Infection my provoke: INFLAMMATION & IMMUNITY
Inflammation may exist w/o: INFECTION (contact mucositis)
_HYPERSENSITIVITY (ALLERGIC DZ)_& _AUTOIMMUNE DZ_ may cause inflammation (W/O INFECTION)
(Immune rxn takes more time to develop than inflammation)

Front 17

Rhematoid Arthritis is an example of what kind of inflammation>

Back 17

Inflammation W/Out INFECTION!!
- Destroys joints, no infection, chronic inflammation

Front 18

Components of Inflammatory responses:
-3

Back 18

1. Circulating Cells & Proteins (w/in blood vasculature/vessels)
2.Cells of the Blood Vessels- Endothelial cells
3. Cells & proteins of the Extracellular Matrix- mass cells, growth factors

Front 19

Inflammation=body's response to Injury:
WHere are most of the defensive elements?
-What are these defesive cells used for in inflammation/ how it works

Back 19

Most of the defensive elements are located in the blood.
- Inflammation is the means by which defensive cells and chemicals leave the blood and enter the tissue.

Front 20

Inflammation is a complex Rxn to Injury- 4 responses/ rxns/

Back 20

1. Vascualr response-allows cells to enter site of injury
2. Cellular response
3. Systemic reactions- fever, etc.
4. Repair

Front 21

Inflammation is:
Excess or Prolonged inflammation may be:

Back 21

Inflammation is: BENEFICIAL
Excess or Prolonged inflammation may be: HARMFUL

Front 22

The inflammatory response Delivers defensive materials: 2

Back 22

1. Leukocytes= DEFNSIVE CELLS
2.Plasma= DEFENSIVE PROTEINS

Front 23

The inflammatory response Delivers defensive materials: 2
1. Leukocytes= defensive ____
2. Plasma= defensive ___

Back 23

1. Leukocytes= Defensive CELLS
2.Plasma= DefensivePROTEINS

Front 24

Collateral damage and destruction due to inflammation:

Back 24

Even though it is meant to help fight the pathogen - need repair mechanism to fix the mess of too much?? ex. CF

Front 25

What are the 5 cardinal signs of inflamation? (Acute?)

Back 25

1. Rubor= Redness
2. Tumor= Swelling
3. Calor= Heat
4. Dolor= Pain
5. Loss of Fx (sprained ankle)

Front 26

Echimosis=

Back 26

blood extravigated from blood vessels

Front 27

All that is red/rubor is it all inflammed?

Back 27

NOOO - could be be do to increase # of blood vessels

Front 28

What are 7 Causes of Acute Inflammation?

Back 28

1. Mechanical Injury -(ex. laceration)
2. Chemical Injury- (ex. eye)
3. Radiation Injury- (ex. sunburm)
4. Thermal Injury-(ex. heat or frost bite)
5. Infection- (ex. urema pus from glans penis)
6. Compromise of Blood Supply- (ex. blod, dianetic w/pvd- gangreen)
7. Immune Injury- (ex. lips= angiodema= immune-mediated)

Front 29

What are the 3 different ways inwhich we can classifiy Inflammation?

Back 29

1. Acute vs. Chronic
2. Exudative vs Non Exudative
3. Clinical Features

Front 30

Clinical & Pathological Definitions of Acute Inflammation:

Back 30

Clinical (intensity/ duration)= Short term & Intense
Patholigcal (histo appearance)= Neautrophils (PMN )

Front 31

Clinical & Pathological Definitions of Chronic Inflammation:

Back 31

Clinical (intensityu/duration)= Longterm & low grade
Pathological (histo appearance)= Lymphocytes, plasma cells, macrophages, leukocytes, more nuclear Cells!!

Front 32

Patterns of Acute inflmmation:
Onset/Duration:
Exudation/nonexuadation:
What cells/how:

Back 32

Onset/Duration: Rapid onset, short duratio (min-days)
Exudation/nonexuadation: EXUDATION of fluid & plasma proteins
What cells/how: EMIGRATION of Leukocytes, prodominantly NEUTROPHILS

Front 33

Patterns of Chronic inflmmation:
Duration:
Cell. nucleus:
What cells/how:

Back 33

Duration: Longer Duration
Cell/nucleus= MONONCLEAR cells- macrophages, lymphocytes, plasma cells
What cells/how: PROLIFERATION of Blood Vessels and Fibroblasts
= NON EXUDATIVE- but blood vessels and fibroblast

Front 34

Exudative= what is it?
where is it found?

Back 34

Fluid that filters from the Vascular space into a site
=Acute Inflammation tends to be more exudative
ex poison ivy

Front 35

Non-Exudative=? what and where found?

Back 35

Chronic Inflammation is frequently non-exudative & is often associated w/fibrosis & scarring.
ex. rhemotoid arthritis

Front 36

Exudative Inflamation
Edema-
Exudate - contents=
Transudate=
Neutrophil=
Pus=

Back 36

Edema=excess fluid.
Exudate - contents= Protein Rich Fluid
Transudate= Protein -poor fluid
neurtphil= response
pus= an exudate rich in neutrophils & debris of dead cell ( combo of neutrophils & necrotic tissue)

Front 37

Clinical Features of Inflammation:
1. Serous inflamation-/Transudate

Back 37

-Blister filled w/low protein moved from vascular system into the tissue

Front 38

Clinical Features of Inflammation:
2.Fibrinous Inflamation-?

Back 38

Ex. Fibrinous percarditis in rhematic fever
Fibrogen surgace of ____??
- ??
-EXUDATE

Front 39

Clinical Features of Inflammation:
3. Suppurative (purlent) inflammation:

Back 39

= forming pus-

Front 40

Clinical Features of Inflammation:
4. Abscess-

Back 40

A localized collection of pus that has accumulated in a tissue cavity, producing fluctance.
(-Fluid filled cavity)
(-FLUCTANCE=Filled w/fluid swelling)

Front 41

Clinical Features of Inflammation:
5. Cellulitis-

Back 41

Diffuse spread of an acute inflammatory process through the fascial planes of soft tissue producing:
a) erythema
b) edema
c) warmth
d) Pain
e) without consolidation
(-inflammatory cells in tissue, not flunctant & not cavity_).

Front 42

Clinical Features of Inflammation:
6. Catarrhal (seromucosa) inflamation-

Back 42

A clinical type of exudative inflammation, occurs only on mucosal surfaces containing mucus-secreting cells, such as nasal or bronchial mucosa
-copous amts of mucous

Front 43

Clinical Features of Inflammation:
7. Ulceration=

Back 43

= Ulcerative inflammation= Recurrent Aphthous Stomatitis
--> An ulcer is a defect in Epithelial continuity
- inlammation type- no epithelium fibrin filled

Front 44

What are the cells of inflammmatory response??

6

Back 44

1. Neutrophil
2. Platelets- fragments of cytoplasm & mega...??
3. Eosinophil
4. Lymphocyte
5. monocyte
6. basophil