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36 Cards in this Set

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IUGR/ Fetal Growth Restriction is a general term for a spectrum of fetal physiologic conditions that result in an infant weighing below the ____ percentile for GA.

10th

A decrease in what is thought to be major physiologic factor on IUGR?

decrease in uterine plasma volume

Maternal conditions which may affetect plasma volume include?

-poor nutritional status


-smoking, drug or alcohol abuse


-TORCH infections


-severe anemia


-diabetes, chronic renal disease, severe chronic asthma, heart disease


-under 17 or over 35 years of age


-high altidue

Placental conditions which may affect plasma volume include?

-placental infarcts and hemangiomas


-small placenta


-single umbilical artery


-abruptio placenta


-placental insufficiency

Fetal conditions which may affect plasma volume include?

-genetic or chromosomal defects


-intrauterine infection

Maternal and placental conditions may cause ____ IUGR.

asymmetric

Fetal conditions may cause ___ IUGR.

symmetric

Growth restricted infants born with diminished stores of fat and glycogen, and are likely to be?

hypoglycemic

Clincal signs of IUGR include?

-uterus measuring small for dates


-history of maternal condition associated with IUGR


Symmetric IUGR is?

growth restriction affecting entire fetus

Symmetric IUGR is often ____ or due to maternal infection.

genetic

Sono findings of symmetric IUGR are?

-all measurements more than 2 weeks below expected gestational age (based on firm LMP or prior study)


- transcerebellar diameter consistent with dates when other parameters are less than expected


-oligohydramnios


-mature placenta earlier than expected


-low BPP score

Asymmetric ( "brain sparing") occurs in the last ___ to ___ weeks of pregnancy.

8-10 weeks

Asymmetric IUGR is asymmetry between the?

head size and abdominal size

Sono findings of asymmetric IUGR are?

-asymmetry of head to body ratio > 2 SD


-AC measureing more than 2 weeks behind HC


-oligohydramnios


-mature placenta earlier than expected


-many complex formulas exist for sono diagnosing IUGR

The most common form of IUGR is?

Asymmetric (75%)

A systolic/diastolic ratio of the umbilical atery > ____ is abnormal after 30 weeks.

3.0

Umbilical artery ratios should be taken?

close to the placental cord insertation because ratios are higher if measured close to fetal cord insertion

What is the normal resistance in second and third trimesters for the uterine artery?

low resistance

Appearance of ___ on uterine artery Doppler waveform is abnormal, and thought to predict placental insufficiency.

"notch"

Normally the umbilical artery should progressively __ during the course of the pregnancy.

decrease

Absent or reversed diastolic flow in the umbilical artery is an ___ sign.

ominous (bad)

Erythroblastosis Fetalis is?

destruction of fetal RBCs by antibodies with subsequent fetal or neonatal complications

Causes of erythroblastosis fetalis are?

-Rh incompatibility


-ABO incompatibility (blood type incompatibility)


-isoimmune disease


-other minor blood group incampatibility

Clinical manifestations of erythoblastosis?

-chronic cheart failure (CHF)


-fetal death


-hydrops fetalis



Hydrops fetalis is?

excessive accumulation of fluid in fetal tissues and body cavities, typically there is interstitial edema, pleural and pericardical effusions and ascites


Immune hydrops is due to?

-Rh (Rhesus) incompatibility, also known as Rh immunization


- occurs with Rh (-) mother and Rh (+) father, (Rh positive fetus)

Improtant Question!!! Know this!!


____ Doppler can help determine likelihood of fetal anemia.

middle cerbral artery (MCA)

MCA is examined close to its orgin from the?

ICA

The angle of US beam and direction of blood flow in MCA should be?

zero degrees

Risk of anemia is highest in fetuses with pre-transfusion peak systolic velocity of ___ times the median or higher.

1.5

Non-immune hydrops is?

hydrops due to any cause other than Rh sensitization

Causes of Non-immune hydrops include?

-cardiac anomalies/ arrhythmia


-infection (TORCH, Fifth disease)


-chromosome abnormalities


-congenital hematologic disorders


-abdominal or pulmonary masses leading to venous obstruction


-twin-to-twin transfustion syndrome

Sono findings in hydrops fetalis?

-pericardial effusion (earliest sign)


-ascites


-fetal skin thickening (anasarca) > 5mm AP


- pleural effusion


-hepatosplenomegaly


-polyhydramnios


-enlarged umbilical vein > 1cm


Sono findings of fetal demise are?

-absent cardiac activity


-exaggerated fetal position (i.e flexion)


-Robert's sign: echogenic foci (gas) in pulmonary vessels or abdomen-delayed finding (about one week after demise)


-Spaulding's sign: overlapping skull bones-also delayed finding (seen about one week after demise)


-fetal maceration

What is a halo effect seen radiographically secondary to subcutaneous scalp edema in fetal demise?

-Deuel's sign/halo sign


-NOT seen on US