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27 Cards in this Set
- Front
- Back
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Class of drug
Cyclophosphamide |
Alkylating agent
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Class of drug
Cisplatin |
Platinums
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Class of drug
Bleomycin |
Antitumor antibiotic
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Class of drug
Methotrexate |
Antimetabolite - folate analogue
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Class of drug
5-Fluorouracil |
Antimetabolite - pyrimidine analogue
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Class of drug
Theoguanine |
Antimetabolite - purine analogue
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Class of drug
Doxorubicin |
Topoisomerase inhibitor
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Class of drug
Etoposide |
Topoisomerase inhibitor
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Class of drug
Paclitaxel |
Antimitotic
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Class of drug
Vincristine |
Antimitotic
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Class of drug
Anastrozole |
Antihormone - aromatase inhibitor - prevents estrogen formation
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Class of drug
Tamoxifen |
Antihormone - estrogen blocker
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Class of drug
Goserelin |
Antihormone - blocks androgen production
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Class of drug
Flutamide |
Antihormone - androgen blocker in prostate
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Class of drug
Filgastrim |
Cytokine - growth factor
- used for neutropenia |
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Class of drug
Ondansetron |
Serotonin receptor antagonist
- GI upset |
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Class of drug
Metoclopramide |
Dopamine receptor antagonist
- gi upset (s/e of cytotoxic drugs) |
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Class of drug
Aprepitant |
Substance P
- GI upset prevention with chemotherapy |
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Class of drug
Dexamethasone |
Corticosteroid
- GI upset prevention with chemotherapy |
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Which classes of cancer meds can be used to damage DNA
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1. Alkylating agents (cyclophosphamide)
2. Platinums (cisplatin) 3. Antitumor abx (Bleomycin) |
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Which cancer meds can be used to inhibit microtubules?
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1. Vinca alkaloids (Vincristine) - binds tubulin
2. Taxanes (Paclitaxel) - binds microtubule |
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Which cancer meds can be used to inhibit DNA synthesis and repair?
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1. Topoisomerase inhibitors (Etoposide and Doxorubicin)
2. Antimetabolites - 5-fluorouracil (pyrimidine analogue) - Theoguanine (purine analogue) - Methotrexate (folate inhibitor) |
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Which cancer meds can be used to block female hormone based cancer
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1. Aromatase inhibitors - Anastrozole
2. Estrogen blocker - Tamoxifen |
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Which cancer meds can be used to block MALE hormone based cancer
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1. Androgen inhibitor - goserelin
2. Androgen blocker - flutamide |
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Which meds can be used to treat gi upset side effect of chemotherapy?
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1. Serotonin receptor inhibitor (Ondansetron)
2. Dopamine receptor inhibitor (Metoclopramide) 3. Substance P (Aprepitant) 4. Corticosteroids (Dexamethasone) |
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Which chemotherapy med creates free radicals?
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Doxorubicin
Bleomycin |
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Which chemo drug has a life time dose maximum? Why?
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Doxorubicin - cardiotoxic
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