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137 Cards in this Set
- Front
- Back
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Atropine Side Effects
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Fever, dry eyes and mouth, tachycardia
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Effective in prevention of migraine headaches but not effective in acute
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Propranolol
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Nystatin mechanism of action
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Binds to ergosterol to disrupt fungal cell membranes
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Route for nitroglycerin
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Sublingual because it bypasses the liver
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AmB adverse reaction
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Nephrotox
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Neuraminidas inhibitor useful in tx or prevention of influenza A and B
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Zanamivir
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Genital herpes tx
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Valacylovir
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Zidovudine SE
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Anemia
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Sumatriptan SE
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Paresthesias and vasospasm
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Brease Cancer Tx
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Tamoxifen
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Tx of Prostate cancer
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Flutamide
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activation of Beta adrenoceptors produces
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tachycardia
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most useful absence seizure tx
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Ethosuximide
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tx onychomycosis
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Terbinafine
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prior to folate tx for megaloblastic anemia, this should be considered to prevent neurological disease
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B12 deficiency
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Hydrocortisone treats this
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Adrenocortical insufficiency
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T/F A cocaine overdose can result in fatal cardiac arrhythmias
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T
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Which herbal has setrogenic properties
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Ginseng
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Exhinacea long term SE
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hepatotox
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can improve atopic dermatitis
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Triamcinolone
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Hypertensive rebound from withdrawl of which drug
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Clonidine
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T/F Prominent diuresis due to carbonic anhydrase inhibition is an attribute of digoxin
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F
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T/F Increased heart rate is an adverse effect of digoxin
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F
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Carbidopa...
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Prevents the breakdown of L-dopa to dopamine in the periphery
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T/F Decreased cardiac output is an action of histamine
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F
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This is a characteristic of alkylating agents used in cancer chemotherapy
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Induction of DNA damage
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Lidocaine...
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is very selective for abnormal cardiac tissue
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T/F Propranol causes torsade de pointes
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F
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This inhibits synthesis of cholesterol by inhibiting HMG-CoA reductase
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Lovastatin
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This binds bile acids in the intestine preventing their return to the liver
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Cholestyramine
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Hypertensive rebound from withdrawl of which drug
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Clonidine
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T/F Prominent diuresis due to carbonic anhydrase inhibition is an attribute of digoxin
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F
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T/F Increased heart rate is an adverse effect of digoxin
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F
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Carbidopa...
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Prevents the breakdown of L-dopa to dopamine in the periphery
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T/F Decreased cardiac output is an action of histamine
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F
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This is a characteristic of alkylating agents used in cancer chemotherapy
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Induction of DNA damage
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Lidocaine...
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is very selective for abnormal cardiac tissue
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T/F Propranol causes torsade de pointes
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F
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This inhibits synthesis of cholesterol by inhibiting HMG-CoA reductase
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Lovastatin
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This binds bile acids in the intestine preventing their return to the liver
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Cholestyramine
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Appropriate antidote for iron toxicity
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Deferoxamine
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Cromolyn action
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mast cell membranes
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Used to treat TB, this imparts a reddish color to sweat and tears
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Rifampin
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Drug for G+ bone infection that causes painful and bloody diarrhea
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Clindamycin
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Diarrhea treatment
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Oral vancomycin
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An antagonistic antibiotic combination
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Ampicillin + tetracycline
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Used in combination with various penicillins to inhibit beta-lactamase activity
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Clavulanic acid
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methicillin and vancomycin resistant staphylococcus aureus tx
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Linezolid
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Lease likely SE with modern loop diuretic
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Hyperkalemia
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Pilocarpine effect
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reduction in intraocular pressure
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T/F Loratadin is an H2 receptor blocker
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F
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Implicated in causing gastric barrier breakdown
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Aspirin
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Greatest degree of beta-2 adrenergic receptor selectivity
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Albuterol
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most effective antidiarrheal action
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Loperamide
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T/F mu opioid receptors are responsible for the antidiarrheal action of Atropine
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F
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T/F Alcohols are effective anivirals
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F
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T/F Iodophors promote rapid release of iodine
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F
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T/F Thyroid hormones decrease cardiovascular activity
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F
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effective tx for hyperthyroidism (4)
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Potassium iodide, Radioiodide (I-131), Propylthiouracil, Methimazole
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Long duration hypothyroidism drug
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Levothyroxine (T4)
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Hormones responsible for calcium regulation (3)
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Parathyroid hormone, Vitamin D, Calcitonin
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binds to hydroxyapatite, reducing bone turnover; useful in tx of Paget's ds
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Etidronate
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T/F - Prescriptions of Schedule IV drugs may be automatically refilled up to five times within a six month period
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F
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Primary tox leading to death from an acetaminophen overdose is
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Hepatocellular necrosis
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A naturally-occuring compound which blocks mitosis for tx of breast cancer
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Palcitaxol
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based on mol weight, this would diffuse across the placenta with the greatest difficulty
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Infliximab (MW - 149,100 Da)
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This profoundly affects fetus development with brief exposure
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Thalidomide
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A plot of drug concentration vs. the percent of recepotor containing bound drug can be used to estimate
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Drug-receptor affinity
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protein that couples a receptor to the inhibition of adenylyl cyclase
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Gi
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Halothane
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is a depressant of respiration
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with inhalation anesthetics, the rate of onset is
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inversely proportional to the solubility of anesthetic gas in the blood
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T/F Nitroglycerin produces Tachycardia
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F
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most likely result in the developlment of hypokalemia, hyperglycemia, hyperuricemia, hypercalcemia, and hypocalciuria
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a thiazide diuretic
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may result in he development of hypokalemia, hyperglycemia, hyleruricemia, and ototox
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thiazide diuretic
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T/F Specificity of action on tumor cells is not a basic proiciple of cancer chemotherapy
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T
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T/F 5-Fluorouracil does not eshibit acute tox
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T
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Parkinsonism is best treated by
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increasing dopamine levels in the central nervous system
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T/F The same dose of lysergic acid dithylamine produces equal effects after oral and parenteral administration
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T
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Has been shown to cause neuronal serotonin depletion and neurotox
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Methylene-dioxy-methamphetamine
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T/F Local anesthetics should not be used in pregnant women
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F
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calcium channel blocker that does not affect cardiac output
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Nifedipine
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reduces the absorption of bile acids from the GI tract
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Colestipol
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Vitamin K is required for
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carboxylation of coagulation factors
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Activation of plasminogen to plasmin
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is catalyzed by urokinase
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enhances cytochrome P450, leading to a reduction in the effectiveness of oral contraceptives
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Rifampin
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Alkalination of the urine with sodium bicarbonate increases excretion of
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a weak acid
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Acetylcholine is lease likely to produce
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Constipation
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Atropine and other muscarinic receptor blockers are most effective in the treatment of
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Motion sickness
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Glucocorticoids regulate all of the following except
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Aldosterone functions
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Salt losers, ammenorhea, virilization
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21 beta hydroxylase deficiency
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Hypogonadism
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17 beta hydroxylase deficiency
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Na+ and water retention, hylokalemia
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11 beta hydroxylase deficiency
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T/F Alkalinization increases reabsorption of weak acids
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F
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Acarbose and slufonylureas can lead to hypoglycemia by acting
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on unrelated biological systems
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T/F the cyt P450 inhibition increases the degradatin of related drugs
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F
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increases the amount of free steroids in the circulation
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Androgen
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T/F Cortisol can increase collagen formation
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F
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T/F Cortisol can decrease osteoclase activity
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F
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has the greatest glucocorticoid activity and the lowest mineral corticoid activity
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Dexamethasone
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prn
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As needed
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T =
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One pill
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The name and amount of each ingredient on a prescription
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Inscription
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Salt losers, virilization, amenorrhea and short stature
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21-beta hydroxylase deficiency
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Cortisol increases plasma levels of
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Sodium
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Cortisol is contraindicated in
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Peptic ulcer, diabetes, and ostroporosis
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Inhibits the conversion of cholesterol to pregnenolone
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Aminoglutrthiamide
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Best steroid prep for chronic inflammation characterized by dryness and scaling
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Ointment
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Ibuprofen
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Binds reversibly to cyclooxygenase
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NSAIDS have no effect on hyperthermia associated with
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heat stroke, Atropoine, or PG injection
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mostly affect cycloxygenase II
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Meloxicam
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Has no effect on production or excretion of uric acid
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Colchcines
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Inhibit TNFa2 in RA patients
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Etanercept
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Inhibit cell wall mycolic acids, causes pyridoxine def
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Isoniazide (INH)
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Inhibit DNA dependent RNA polymerase, induce cyt p450, gives orange to red color to body secretions
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Rifampin
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Most associated with arthropathy of cartilage
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Ciprofloxacin
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Expired prepartion associated with systemic lupus and Facony syndrome
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Tetracyclin
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Rapid injection is associated with redneck, redman syndrome
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Vancomysin
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Is the lease associated with pseudo membranous colitis
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Vancomycin
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Inhibit cell wall synthesis
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Penicillin
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Interact at 30s protein
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Tetracyclin
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Interact at 50s protein
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Chloramphenicol
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Compete with PABA for dihydropterte synthesis
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Sulfadiazine
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Has the lease sedative property
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Astemizole
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Is useful as a local anesthetic
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Diphenhydramine
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Is a sulfonylurea with the longest duration of action and most associated with hypoglycemia
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Chlorpropamide
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Short acting, useful for IV injection insulin
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Crystalline zinc
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Is an inhibitor of insulin secretion
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alpha adrenergic agonists
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Is mainly used for inhibiting H+, K+ proton pump
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Omeprazole
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This antacid can cause constipation and milk alkali syndrome
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Calcium carbonate
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Inhibit hydrolysis of acetylcholine by inhibiting acetlycholine esterase
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Neostigmine
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Antibacterial, an absorbent and decreases motility
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Bismuth
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Activate pre-synaptic D2 dopamine R
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Metchopramide
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Most associated with red urine and stool laxative
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Phenolphthalein
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T/F Viruses are independent from the host cell for replication
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F
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Most useful for oral single-drug therapy of vaginal or urinary tract fungal infection
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Fluconazole
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mechanism of action of itraconazole
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inhibits ergosterol synthesis
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antifungal agent most associated with the production of nephrotoxicity
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AmB
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