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28 Cards in this Set
- Front
- Back
- 3rd side (hint)
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What is hyperplasia?
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increased number of cells
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cell mutation
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What is dysplasia?
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abnormall proliferation of cells w/loss of size, shape, and orientation
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cell mutation
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What is metaplasia?
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1 cell type is replaced by another adult cell type
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Which classification has more to do with prognosis?
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grade
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What criteria are used for staging?
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TMN, tumor size, metastases, node involvement
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infection
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invades and causes damage to cells in host; disrupts normal body function
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what does it do in the host?
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adenoma
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benign epithelial neoplasm, or a neoplasm derived from glands
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what type of neoplasm?
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sarcoma
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malignant neoplasm, derived from mesenchymal tissue
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what type of neoplasm?
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carcinoma
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malignant neoplasm derived from epithelial tissue
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adenocarcinoma
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carcinoma in which the lesion begins to grow in gland patterns
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teratoma
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consists of more than one germ layer;
well differentiated=benign, not well differentiated=malignant |
describe teratoma type tumor/lesion
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leiomyoma
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benign; found in smooth muscle; often in uterine wall
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lymphoma
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malignant lymphocytic neoplasm
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dysplasia
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disorderly but non-neoplastic proliferation of cells
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None
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oncogenes
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mutated forms of DNA, which no longer effectively regulate cell replication
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properties of benign neoplasms
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well differentiated; usually progressive and slow growth; mitotic figures are rare and normal; do not invade surrounding tissue; no metastases occurs
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properties of benign tumors
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malignant neoplasms
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lack of cell differentiation w/ anaplasia; erratic growth; mitotic figures numerous and abnormal; locally invasive; metastatic into other areas
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describe difference of malignant neoplasm vs. benign
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3 classes of hereditary forms of cancer
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1)inherited cancer syndromes(autosomal dominant)
2)familial cancers 3)defective dna repair(autosomal recessive) |
None
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tumor grade
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based on level of differentiation and the # of mitoses
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tumor stage
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more important for prognosis; based on size of lesion and extent of spread
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mononuclear inflammation is what type of response?
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acute response to intracellular parasite
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None
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carbuncle
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localized bacterial infect. of skin and subcutan. tissue; several openings discharging pus
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furuncle
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circumscribed pus-filled inflammation of skin and subcutaneous tissue often b/c of staph. infection
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None
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major clinical consequences of atherosclerosis
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MI, cerebral infarction, aortic aneurysms, peripheral vascular disease, chronic ischemic heart disease
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heart disease resulting from hardening of arteries:
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unchangeable risk factors for heart disease (3)
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old age, male, genetics
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None
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changeable risk factors
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hyperlipidemia, hypertension, smoking, diabetes
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3 main components of acute inflammation
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1.inc. vascular permeability 2.vasodilation 3.PMN emigration
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3 main components of chronic inflammation
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1.infiltration of mononuclear cells 2.tissue destruction 3.attempted repair
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