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27 Cards in this Set
- Front
- Back
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Cancer caused by hepatitis B virus
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hepatocellular carcinoma
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cancer caused by hepatitis C virus
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hepatocellular carcinoma (liver cancer)
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GAG codes for
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structural proteins
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POL codes for
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reverse transcriptase, protease, integrase
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ENV codes for
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viral envelope protein that recognizes the cell surface receptor for the retrovirus
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cancer caused by HTLV-I (human T-cell lymphotropic virus)
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acute adult T cell leukemia
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cancer caused by HTLV-II (human T-cell lymphotropic virus II)
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hairy cell leukemia
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E6 binds to and causes degradation of
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the growth suppressor p53
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The two early gene products ______ appear to be essential for transformation by human papillomaviruses (HPV).
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- E6 and E7 -
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E7 binds to and inactivates
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retinoblastoma protein (RB), which normally acts as a negative regulator of the cell cycle by binding to and inactivating the transcription factor E2F1.
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cancer caused by human papilloma virus - 6 (HPV-6)
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oral cancers of squamous cell origin
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vaccines against HPV (human papilloma virus)
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gardasil
Cervarix |
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Gardasil protects against
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HPV-16, 18 (the types causing cervical cancer), as well as against 6 and 11 (the types causing genital warts, but rarely cancer)
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Cervarix protects against
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HPV-16, 18 (the types causing cervical cancer) only
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cancers caused by HPV-16 and 18
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cervical cancer
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HPV-6 and 11 cause
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genital wars, rarely cancer
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HPV-5 causes
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epidermodysplasia verruciformis (EV) - skin lesions that resemble flat warts
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the etiologic agent in papillomas of the genitalia, known as Condyloma acuminatum (CA) or genital warts
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human papilloma virus
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gene essential for transformation of SV40 (polyomavirus)
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large T antigen
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gene essential for transformation polyoma (polyomavirus)
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middle T antigens
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Large T antigen: SV40 :: E6 and E7: ______
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human papilloma virus (HPV)
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BK and JC polyomaviruses are established in
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the urinary tract
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JC polyomavirus can spread to the ____ and cause
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the brain
progresive multifocal leukoencephalopathy (PML) |
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cancers associate by Epstein-Barr virus
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Burkett's lymphoma
nasopharyngeal carcinoma |
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cancer associated with human herpesvirus 8
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kaposi sarcoma
body cavity-based B-cell lymphomas in AIDS patients |
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Chronic carriers of HBV have a ____ times greater risk of eventually developing liver cancer.
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300
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Worldwide, HBV is responsible for _____of all liver cancer cases
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60%
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