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27 Cards in this Set

  • Front
  • Back
actin
smooth muscl cells, myofibroblasts, myoepithelial cells
alpha-fetoprotein
hepatocytic and hepatoid, yolk sac tumors, germ cell tumors
CA19-9
colonic carcinomas, pancreatobiliary adenocarcinomas, transitional cell carcinomas
CA-125
adenocarcinomas of ovary, cervix, endometrium, GI tract, thyroid, breast
Calretinin
+ for mesothelioma, - for lung adenocarcinoma
CEA
carcinoembryonic antigen

adenocarcinomas of GI tract (including pancreas) and lung
CD31
endothelial cells
CD99
Ewing's sarcoma / PNET (primitive neuroectodermal tumor)
CD117
GIST tumor family (gastrointestinal stromal tumor)
CDX2
adenocarcinomas of intestinal origin
Chromogranin
neurosecretory granules
Desmin
smooth and skeletal muscle
EMA
epithelial membrane antigen

epithelial
Factor VIII-related antigen
endothelial cell differentiation
HMB-45
melanocytic origin and neural crest-derived tumors
Keratins
epithelial cells
LCA
CD3
UCHL-1
CD20
CD79a
leukocyte common antigens: Lymphoid differentiation
T-lymphocyte
T-lymphocyte
B-cell
B-cell
Melan-A
melanocyte
Myogenin
skeletal muscle
Myoglobin
striated (skeletal and myocardial muscle)
NSE
neuron-specific enolase

neurons and neuroendocrine cells
PSA
prostate-specific antigen

prostate
S-100
glial and Schwann cells; malnocytes, chondrocytes, adipocytes, myoepithelial cells
Synaptophysin
neuroectodermal and neuroendocrine
TTF-1
thyroid transcription factor-1

thyroid carcinoma and lung carcinoma (including small cell neuroendocrine type). used in differential between primary lung carcinoma and carcinomas of other sites
vimentin
mesenchymal origin (endothelial cells, fibroblasts, smooth muscles)
CA 15-3
breast carcinoma