Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
3 Cards in this Set
- Front
- Back
What are gp100
tyrosinase MART1? |
Tumoar associated antigens in
melanoma |
|
TGF-b in immunosuppression in tumors?
|
Inhibits T cell function
Induces conversion of CD4 effector to Treg, which inhibits trafficking and antigen presentation in DCs |
|
Sipuleucel-T
|
First FDA approved cancer vaccine
Contains: APCs isolated from patient's blood PAP/GM-CSF fusion protein GM-CSF activates and recruits DCs used for prostate cancer |