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4 Cards in this Set
- Front
- Back
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3 basic descriptors of tumors
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clonal origin
unregulated growth altered tissue specificity |
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what types of tumors are immunogenic?
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chemical or radiation induced (altered self)
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Tumor versus Cancer antigens?
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Tumor antigens are only on tumor cells, are unique to each tumor, products of oncogenic viruses
cencer antigens restricted to gamatogenic tissues and cancer, frequently on X chrom., indiciative of metastatic potential |
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Treg cells
-job -definition -expresses -activated by -suppressed by |
-suppress response to self
-CD4+CD25+ T cells -express CTLA-4 -activated by IL2 -suppressed by IFNgamma |
