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15 Cards in this Set

  • Front
  • Back

Anoxia

Lack of oxygen to the brain

Complex focal seizures

seizure disorder that produces a blank stare, disorientation, repetitive
actions, and memory loss.

Eclampsia

A life-threatening condition that can develop in pregnant women that causes high blood
pressure and seizures.

Hirsutism

Excessive growth of body hair (especially in women).

Myoclonic seizure:

Seizure that is characterized by jerking muscle movements and is caused by
contraction of major muscle groups.

Simple focal seizures

Seizure that affects only one part of the brain and causes the person to
experience unusual sensations or feelings.

Status epilepticus

Medical emergency brought on by repeated generalized seizures that can
deprive the brain of oxygen.

Tonic-clonic (grand mal) seizures

Generalized seizure that causes stiffening of the limbs, difficulty
breathing, and jerking movements and is followed by disorientation and limbs that become limp.

HYDANTOINS

Phenytoin and fosphenytoin suppress seizure activity by binding to receptors on voltage-dependent
sodium channels

VALPROATES

Valproates are described as “broad-spectrum” antiseizure drugs because they are effective in treating
all types of seizures.

IMINOSTILBENES

There are only two antiseizure medications in this class, carbamazepine and oxcarbazepine. They are
used to treat generalized and complex focal seizures.

γ-AMINOBUTYRIC ACID ANALOGS

Gabapentin, pregabalin, tiagabine, and vigabatrin are administered for the treatment of general and
partial (focal) seizures.

SUCCINIMIDES

Ethosuximide and methsuximide are indicated for the treatment of absence seizures

BARBITURATES

Phenobarbital was the first drug used to treat seizures. It is indicated in the treatment of
generalized tonic-clonic seizures and partial seizures and is administered to children to control
febrile seizures. Amobarbital, mephobarbital, and primidone are also administered to treat tonicclonic
seizures. Pentobarbital is indicated for the treatment of status epilepticus and acute
control of tonic-clonic seizures from meningitis, tetanus, ethanol withdrawal, eclampsia, and
poisons.

OTHER BROAD-SPECTRUM ANTISEIZURE DRUGS

Lamotrigine, levetiracetam, topiramate, and zonisamide are newer broad-spectrum antiseizure drugs.