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11 Cards in this Set
- Front
- Back
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OATP
1A2 |
enterocyte/prox tub
apical subs: fexofenadine inh: rifampin, FJ |
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OATP
1B1 |
hepatocyte (basolateral)
subs: statins, MTX, rifampin inh: rifampin, macrolides, cyclosporine |
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OATP
1B3 |
hepatocyte (basolateral)
subs: rifampin, digoxin, MTX, fexo, prav, fluva, rosu inh: rifampin, macrolides, repaglinide |
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OATP
2B1 |
hepatocyte (BL) entero (apical)
BBB, placenta subs: fluva, ator, fexo, benzylpen inh: NONE |
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OCT1
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hepatocyte (basolateral)
subs: lamivudine, zalcitabine, metformin inh: verapamil, montelukast, ritonavir |
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OCT2
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proximal tubule (basolateral)
subs: cimetidine, amantadine inh: NONE |
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OCT3
|
enterocyte (apical)
hepatocyte (BL) sub: cimetidine inh: NONE |
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OAT1
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prox tubule (basolateral)
subs: cimetidine, simvastatin inh: probenecid |
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OAT2
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hepatocyte/prox tub (basolateral)
subs: zido, 5-FU, taxol, ceph, NSAIDs, tetracyclines inh: prav, probenecid |
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OAT3
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prox tub (BL)
subs: famotidine, ranitidine, MTX, ceph, diuretics, NSAIDs inh: probenecid, NSAIDs |
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OAT4
|
proximal tubule (apical)
subs: tetracycline, MTX, NSAIDs, zido, prava, cephs inh: probenecid |
