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13 Cards in this Set
- Front
- Back
Probenecid with:
Penicillin ACE Inhibitors Antivirals |
probenecid inh OATs
decreases renal clearance incr half-life |
|
Cimetidine with:
Procainamide Levofloxacin Dofetilide |
cimetidine inh OCT, OAT, OATP
decr renal clearance increased AUC |
|
Fruit Juices with:
fexofenadine |
FJ inh OATPs
decr plasma levels of fex |
|
NSAIDs or Probenecid with:
methotrexate |
Probenecid and NSAIDs inh
OAT3 decr renal cl of MTX |
|
Quinidine with:
loperamide |
quinidine inh MDR1
incr CNS ADE of loperamide |
|
verapamil with:
talinolol |
verapamil inh MDR1
decr plasma levels of talinolol |
|
erythromycin with:
fexofenadine |
erythro inh MDR1
incr plasma levels of fex |
|
rifampin with:
fexofenadine |
rifampin induces MDR1
decr plasma levels of fex |
|
Quinidine, Verapamil, Talinol, Clarithromycin, Statins with:
digoxin |
inhibitors of MDR1
incr plasma dig levels decr renal clearance |
|
rifampin with:
digoxin |
rifampin induces MDR1
decr plasma dig levels |
|
troglitazone
|
inhibits BSEP
hepatotoxicity |
|
bosentan
estrogens cyclosporine |
inhibits BSEP
cholesthiasis |
|
cidofovir
adefovir cehaloridine |
inhibit OAT1
nephrotoxicity |