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13 Cards in this Set

  • Front
  • Back
Probenecid with:
Penicillin
ACE Inhibitors
Antivirals
probenecid inh OATs
decreases renal clearance
incr half-life
Cimetidine with:
Procainamide
Levofloxacin
Dofetilide
cimetidine inh OCT, OAT, OATP
decr renal clearance
increased AUC
Fruit Juices with:
fexofenadine
FJ inh OATPs
decr plasma levels of fex
NSAIDs or Probenecid with:
methotrexate
Probenecid and NSAIDs inh
OAT3
decr renal cl of MTX
Quinidine with:
loperamide
quinidine inh MDR1
incr CNS ADE of loperamide
verapamil with:
talinolol
verapamil inh MDR1
decr plasma levels of talinolol
erythromycin with:
fexofenadine
erythro inh MDR1
incr plasma levels of fex
rifampin with:
fexofenadine
rifampin induces MDR1
decr plasma levels of fex
Quinidine, Verapamil, Talinol, Clarithromycin, Statins with:
digoxin
inhibitors of MDR1
incr plasma dig levels
decr renal clearance
rifampin with:
digoxin
rifampin induces MDR1
decr plasma dig levels
troglitazone
inhibits BSEP
hepatotoxicity
bosentan
estrogens
cyclosporine
inhibits BSEP
cholesthiasis
cidofovir
adefovir
cehaloridine
inhibit OAT1
nephrotoxicity