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25 Cards in this Set
- Front
- Back
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Iron |
3-5 g in body Cofactor O2 binding |
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Ferric state |
Found in food 3+ |
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Ferrous state |
Absorbable 2+ |
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Iron deficiency |
15% of pop See decrease in ferritin first |
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Primary iron overload |
Hereditary hemochromatosis Iron builds up in organs |
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Secondary iron overload |
Excess intake |
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% Saturation |
(Total iron/ TIBC) X 100 |
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TIBC |
250-425 |
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Copper |
Mainly cofactor Iron reduction |
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Copper deficiency |
Uncommon Pre-mies |
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Menkes Disease |
Cu is deposited but not release Pts life expectancy is ~5 years |
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Copper excess |
Dietary intake |
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Wilson's Disease |
Cu builds up in liver and brain Manifests between 6 - 40 years old Can impair neurological fxn Zinc acetate therapy |
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Zinc |
Influences ~300 enzymes Glycolysis, growth factor, membrane structures |
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Zinc deficiency |
Malnutrition Decreased T-cell fxn Severe cases result in death |
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Zinc Excess |
Usually nontoxic Fumes from factories can be fatal |
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Chromium |
Hexavalent Carcinogen Trivalent Maintains glucose metabolism |
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Cobalt |
B 12 fxn Helps RBCs develop |
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Flouride |
Teeth |
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Manganese |
Forms metalloenzymes Enzyme activator |
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Molybdenum |
Cofactor |
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Selenium |
Considered carcinogen until it's not Metabolizes free radicals |
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Keshan Disease |
Endemic cardiomyopathy Seen in china |
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Keshin-Beck Disease |
Endemic osteoarthritis |
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Selenium sulfide excess |
Chronic exposure to antifungals and anti dandruff |
