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33 Cards in this Set
- Front
- Back
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toxic principle of lupine and mode of action
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quinolizidine alkaloids
-stimulation of nicotinic acetylcholine receptors |
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scientific name for lupine
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lupinius
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clinical signs of lupine ingestion
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seizures
ataxia head pressing salivation |
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treatment and prognosis of lupine ingestion
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no antidote
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toxic principle of locoweed and mode of action
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swainsonine
-inhibits alpha mannosidase (causes neuronal swelling and dysfxn) |
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scientific names for locoweed
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oxytropis, astralagus
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clinical signs of locoweed consumption
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belligerent
depression ataxia excitable loss of sense of direction |
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treatment and prognosis of locoweed toxicity
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horses unsafe to ride, addiction occurs (peer pressure)
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scientific name for larkspur
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delphinium
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toxic principle and mode of action of larkspur
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polycyclic diterpene alkaloids
-neuromuscular blocking agents (competes with acetyl choline) |
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scientific names for locoweed
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oxytropis, astralagus
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clinical signs of locoweed consumption
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belligerent
depression ataxia excitable loss of sense of direction |
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treatment and prognosis of locoweed toxicity
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horses unsafe to ride, addiction occurs (peer pressure)
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scientific name for larkspur
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delphinium
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toxic principle and mode of action of larkspur
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polycyclic diterpene alkaloids
-neuromuscular blocking (competes with acetyl choline-competitive inhibition) |
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clinical signs of larkspur toxicity
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nervousness
paresis (weakness) salivation tremors excitement bloat sudden death |
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treatment and prognosis of larkspur toxicity
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detoxify-activated charcoal, cathartics
physostigmine |
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scientific name for braken fern
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pteridium aquilinium
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toxic principle and mode of action of braken fern toxicity
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thiaminase -Vit B deficiency-cell shortage of ATP
ptaquiloside- bone marrow depression |
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clinical signs of braken fern toxicity
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ataxia
weakness blind staggers weight loss head pressing death |
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treatment and prognosis of braken fern toxicity
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long term exposure is guarded
thiamine administration |
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scientific name for poison hemlock
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conium maculatum
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toxic principle and mode of action of poison hemlock
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coniine alkaloid
-stimulation and paralysis of nicotinic receptors (muscle stimulation and paralysis) |
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clinical signs of poison hemlock toxicity
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nervous
convulsions salivation bloat coma sudden death |
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treatment and prognosis of poison hemlock toxicity
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unlikely anything will change outcome
-evacuate stomach, respiratory support -good prognosis with treatment |
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scientific name for water hemlock
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cicuta
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toxic principle and mode of action of water hemlock
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cicutoxin
-seizure induction |
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clinical signs of water hemlock toxicity
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violent seizures
salivation muscle twitching chomping of jaws coma, death |
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treatment and prognosis of water hemlock toxicity
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no antidote-will die
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scientific name for groundsel and fiddleneck
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groundsel-Senecio vulgaris)
fiddleneck-Amsinickia |
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toxic principle and mode of action of groundsel and fiddleneck
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pyrrolizine alkaloids
-alkylate DNA -liver cell necrosis and vascular lesions |
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clinical signs of groundsel and fiddleneck toxicity
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depression
anorexia head pressing, aimless walking ataxia drowsiness |
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treatment and prognosis of groundsel and fiddleneck toxicity
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no antidote, supportive care
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