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8 Cards in this Set
- Front
- Back
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What are pyrethrins and pyrethroids?
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-used for flea and tick control in dogs and cats
-used for sprays and dips -extracts from chysanthemums |
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What is the mechanism of action of pyrethrins and pyrethroids?
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-delay closure of sodium ion channels in the axonal membrane (knock down effect)
-may inhibit ATPase leading to repetitive -calls allergic reactions (esters) -type 2 ptrethroids interfere with GABA and glutamic acid |
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What are the clinical signs associated with pyrethrins?
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-salivation
-vomiting -diarrhea -hyperexcitability -tremors -seizures -dyspnea -prostration -death |
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What are the lesions associated with pyrethrins?
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no specific lesions
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How do you diagnose pyrethrins in a lab?
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-low tissue levels
-difficult to detect -specimens are liver and brain -tissue levels are not well correlated with severity of clinical signs |
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How do you diagnose pyrethrins?
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history
clinical signs rule out other diseases |
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How do you treat pyrethrin toxicosis?
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Treat symptomatically
-diazepam for anticonvulsants -phenothiazines are coutraindicated -wash skin with soap and water |
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What is the prognosis of pyrethrin toxicosis?
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excellent
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