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9 Cards in this Set

  • Front
  • Back
What are plants with dimethyl disulfide?
What is the MOA?
Signs?
mustards

contains 5 methyl cysteine sulfoxide which is reduced by intestinal flora in monogastrics and rumen microflora to dimethyl disulfide
causes heinz bodies

see anemia, depression, hemoglobinemia, cyanosis
What are plants with diterpene esters?
MOA?
Signs?
spurge family
poinsettia

causes direct irritation of the skin of the skin and mucous membranes

signs are mild in SA but severe in horses
What are plants with grayantoxins?
heath family
azaleas

bind to sodium channels in excitable cells
increases permeability of sodium ions and depolarization
irritation of GI mucosa

see excessive salivation, vomiting, regurgitation, colic and diarrhea
What are plants with lectins?
casterbean
bean

inhibits cellular protein synthesis resulting in cell death

see GI signs including hemorrhagic gastroenteritis
What are plants with meliatoxins?
sources
-tetranortriterpenes
-alkaloid
-resin
-plant
-chinaberry

entero and neurotoxic

see GI signs with or without blood
CNS and peripheral neuronal signs generally similar to nicoteine poisoning
death is from respiratory failure
What are plants with propyl disulfide toxin?
onion, garlic, shallots, chices, leek

oxygen free radicals wich damage RBC membraines

see anorexia, ataxia, tachycardia, dyspnea, icterus, anion odor and abortion
What are plants with tetradymol?
horshbrush - sunflower family

causes induction of microsomal enzymes
causes liver damage

sheep are most susceptible
seen anorexia, depression, incoordination, dyspnea and probably icterus and head pressing
What are plants with Thiaminase?
horse tail
bracken fern

thiaminase destroys thiamine in the diet and produces signs of thiamine deficiency in monogastrics
What are plants with triterpenoid saponins?
alfalfa
holly
ginsing
pokeweed

causes direct irritation of the GI mucosa

see salivation, anorexia, vomiting, diarrhea, colic and hypothermia