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14 Cards in this Set
- Front
- Back
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What is the source of metaldehyde?
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Slug and snail bait
-Palatable |
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*What species are susceptible to metaldehyde toxicosis? Most commonly affected?
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All animals, most commonly dogs
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What is the toxic dose of metaldehyde for a 22lb dog (10 kg)?
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~65 grams (3%)
-100-400 mg/kg BW |
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What is the mechanism of action of metaldehyde?
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Acetaldehyde is liberated by gastric hydrolysis
-precise mechanism of action unknown |
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****What are the primary clinical signs of metaldehyde toxicosis?
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"Shake and bake syndrome"= muscle tremors + hyperthermia
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*Where do the muscle tremors from metaldehyde begin?
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Fine motor tremors start at head
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What are 3 ways to diagnose metaldehyde toxicosis?
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1) History of potential exposure
2) Appropriate clinical signs -muscle tremors, lack of lesions 3) Chemical analysis |
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**What are the best specimens to perform chemical analysis on if you suspect metaldehyde toxicosis? How should it be preserved?
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Frozen stomach/intestinal contents
Preserve in air tight container |
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**What are the 5 primary components of metaldehyde treatment?
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1) Control seizure activity / muscle tremors
2) Decontamination 3) Airway management 4) Fluids 5) Control hyperthermia |
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*What are the 4 ways to decontaminate an animal with metaldehyde toxicosis?
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1) *Emetics
2) *Gastric lavage 3) Activated charcoal 4) *Enemas |
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What are 2 reasons to give fluids for metaldehyde toxicosis?
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1) Bicarbonate
2) Maintain cardiovascular support |
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What are 3 ways to control hyperthermia in animals with metaldehyde toxicosis?
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1) Stop tremors
2) Fluids 3) Baths, cold water enemas etc |
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What is the prognosis of metaldehyde toxicosis?
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Most recover w/ effective management (24 hours)
-Guarded to good, depends upon dose at time of presentation |
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What are the long term sequelae of metaldehyde toxicosis?
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Renal and hepatic dysfunction could occur
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