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8 Cards in this Set
- Front
- Back
What is the source of hydrogen sulfide?
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liberated from the decomposition of urine and feces in the underfloor wast pits, deep litter, manure packs, sewage and other organic matter containing sulfur
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What are the properties of hydrogen sulfide?
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colorless and has an odor of rotten eggs
heavier than air flammable irritant forming sodium sulfide with moist mucous membranes |
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What is the toxicity of hydrogen sulfide?
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most dangerous sewage gas
humans can detect.005 -.1ppm 20ppm causes irritation 50ppm can cause sever symptoms 1000 ppm cause rapid unconsciouness and death in about an hour sudden exposure to 400ppm may be quickly fatal |
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What is the toxicokinetics of hydrogen sulfide?
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readily absorbed though the lungs and GI tract
converted to alkali sulfates in the blood -the hydrosulfide radical is normally oxidized to sulfate and is excreted in urine -some is excrete in feces |
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What is the mechanism of action for hydrogen sulfide?
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dirrect irritation of mucous membranes
inhibition of cellular repiration by inhibiting cytochrome oxidase |
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What are the clinical signs of hydrogen sulfide?
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large concentration may cause sudden collapse, cyanosis dyspnea, anoxic convulsions, signs of irritation to ocular, respiratory mucosa and lungs as in ammonia
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What are the lesions associated with hydrogen sulfate?
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-compatible with clinical signs
-the blood is dark and may not clot -the tissues may be dark or greenish purple -if congested the GI contents may be black or dark gray and have sewage odor |
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How do you treat hydrogen sulfide toxicosis?
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removal of source
sodium nitrite IV may be partly effective by forming methemoglobin that binds the hydrated sulfide radical and reactive cytochrome oxidase oxygen and supportive therapy |