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30 Cards in this Set
- Front
- Back
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What is the MoA of phenoxyacetic acid?
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(1) increase nitrate or cyanide in the plant
(2) make more palatable -in animals --> cause increased irritability of skeletal muscle |
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What are the systems affected with phenoxyacetic acid toxicosis?
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GI, Muscle
-myotonia -paresis in hind limbs |
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What are the 2 sources for dipyridil herbicides?
-what is the main difference |
paraquat - free radicals cause fibrosis in the lung
diquat |
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What are clinical signs with paraquat toxicosis at high and low doses?
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-High --> CNS, convulsion (<2 hours)
-Low--> GI, respiratory, renal (called the hit and run) (1-3 days) |
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What are clinical signs with diquat toxicosis at high and low doses?
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-High --> CNS, convulsion (<2 hours)
-Low--> GI, renal (called the hit and run) (1-3 days) |
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Which herbicide is the most common contaminate of well water?
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triazine --> atrazine (problems with the frogs)
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What are the main systems affected with triazine herbicides?
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CNS in cattle (cattle get into bags)
-hyperesthesia, muscle tremors |
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Is use of atropine a good idea with thiocarbamate toxicity/
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no - b/c it is not a AChE inhibitor
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What system does glycophosate, a glycine base herbicide affect? (ROUNDUP)
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GI
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What fungicide gives seed its pink color and what clinical signs does this fungicide cause?
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Captan
-respiratory signs (dyspnea) |
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How is toxicity from carbamate fungicides normally gotten?
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grain overload
-Thiram is most hazardous |
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What are the clinical signs seen with surfactants?
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CNS (cationic), GI, RBC (anionic)
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What about automatic dishwasher detergents can make them caustic?
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the Ca builders
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What are the 3 types of disinfectant cleaners?
Which ones are highly toxic to cats? |
(1) phenolic
(2) pine oil (3) cationic surfactant -Phenolic and pine oil |
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What is unique about phenolic disinfectant cleaners?
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-denature and ppt. proteins
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What are the clinical signs of disinfectant cleaners?
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GI, CNS (cationic) and hepatic (phenol/pine oil)
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What is the worst prognosis of all household cleaners?
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drain cleaners
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What type of necrosis is seen with drain cleaners (basic)?
-toilette bowl cleaners (acidic)? |
liquifactive necrosis (pH>12) --> keep penetrating tissue
coagulative necrosis (pH<2) --> LESS PENETRATION |
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What is the most toxic of the bleeches?
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mildew removal
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What are considered corrosive?
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-cationic surfactants, pine oils, phenols, bleach, ammonia greater than 5%
-ALL oven cleaners/drain cleaners |
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What should not be combined with corrosive acids?
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bases - due to exothermic reaction
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What are contraindications for vomiting?
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extreme depression, excitation, corrosive ingestions, volatile hydrocarbons
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What is the most volatile household hydrocarbon?
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furniture polish
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What are the systems affected with hydrocarbons?
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CNS depression, respiratory (due to aspiration)
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What is the general treatment for hydrocarbons?
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- if > 1ml/kg --> induce vomiting
-DONT induce vomiting with furniture polish or < 1ml/kg |
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What is in fertilizers?
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nitrates
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What is the clinical signs seen with nitraties?
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GI in SA
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What is the problem with rose fertilizers?
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lots of Fe
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What types of things is activated charcoal useful for?
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-anionic surfactants, cationic surfactants, disinfectants, hydrocarbons
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What is activated charcoal bad for?
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acids or alkaline products
-small, inorganic compounds (fertilizer, iron) |
