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7 Cards in this Set
- Front
- Back
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What are paraquats?
Diquats? |
P: broad spectrum restricted use pesticides used to spray herbs
D: brad spectrum general use pesticide to spray herbs highly toxic |
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What is the MOA for para and diquat?
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reduce by nicotinamide-adenine dinucleotide phosphate (NADPH to produce singlet oxygen
-reacts with lipids of the cell membrane -production of free radial and membrane necrosis |
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What are clinical signs?
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acute
-vomiting, anorexia and depression -high doses - ataxia, dsypnea delay -cyanosis, harsh resp sounds, reduced pulmonary compliance chronic -pulmonary fibrosis |
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What are the lesions with Paraquat and diquat?
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mainly in respiratory tract
see congestion, edema, hemorrhage lingual ulcers liver, kidney and spleen congestion |
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How do you lab diagnose paraquats?
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stomach contents
urine (after 48 hours) |
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How do you treat paraquats?
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no specific antidote
detox -emetics -saline carthartics supportive -O2 (can be contraindicated) |
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What is the prognosis of paraquats?
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guarded or grave
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