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28 Cards in this Set

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What is the main cause of toxic poisonings in children?

Alcohol

Why are children more prone to toxic exposure?

Curiosity

What is the mechanism of APAP toxicity?

Metabolites

Antidote for heparin

Protamine

Chronic dependence of opioids. treatment?

Naltrexone


(50 MG daily =MD)

Naloxene is the antidote for what?

The acute treatment of opiate poisoning

Cyanide poisoning antidote?

Sodium and Amyl nitrite/ sodium thiosulfate

Irons antidote

Deferoxamine

Flumazenil

Antidote for benzodiazepines

Antidote for warfarin

Vitamin K

The antidote for salicylates and tricyclic antidepressants?

Sodium bicarbonate

What is the AC- to drug ratio? And the recommended amount if the amount of drug ingested is unknown?

10:1 ratio give 0.5-2g/kg or as much as can be tolerated

Activated charcoal

Most likely complication of activated charcoal?

Vomiting

Aspiration of bowel perforation is less likely

Define MDAC

Administration of >2 sequential does = multiple-dose activated charcoal

What is WBI?

A method of flushing out the GI tract due to poisoning using a polyethylene glycol and electrolyte solution.

This preparation prevents electrolyte abnormalities associated with sodium phosphate

Why shouldn't Miralax (commonly used in kids for constipation) be used for WBI?

Miralax has NO electrolytes!

What is the most commonly identified cause of acute liver failure in children?

Acetaminophen (Tylenol)

Involved in more than 10% adult poisoning fatalities

Define acetaminophen induced hepatotoxicity (liver)

Aspartate aminotransferase concentrations >1000 IU/L

Define fulminant

(Of a disease or symptom) severe and sudden in onset

What might patients experience with stage 3 liver damage?

Fulminant hepatic failure, encephalopathy, coma, and hemorrhage.

What is the cause of death due to acetaminophen overdose?

MOD- multiple organ damage

Occurs in 3-5 days in Stage 3

Intoxication

Maladaptive behavioral or psychological change that develops after a recent ingestion of alcohol or other drugs.

Withdrawal

Syndrome after the cessation of (or reduction in) use that is heavy and prolonged to induce intoxication

What is the active ingredient in maijuana?

Delta-9-tetrahydrocannabinol (delta-9-THC)

This active ingredient is a partial agonist

What is nystagmus?

Rapid involuntary movements of the eye

What is given for acute opioid reversal?

Naloxone given repeatedly as needed

When is flumazenil administered?

Acute intoxication with benzodiazepines including flunitrazepam

When would methylene blue treatment be used?

Methemoglobinemia due to inhalant intoxication