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34 Cards in this Set

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What is the source of rotenone?
roots of the Derris plants
What is the use for rotenone?
in flea control products
premise insecticides
control of external parasites, intentional killing of fish in lakes
What is the absorption and metabolism of rotenone?
absorption- good in oily food, metabolized in the liver to toxic(-OH) and nontoxic products
What spp. is most sensitive to rotenone toxicity?
cats and birds
What are some clinical signs you can see with rotenone toxicity?
vomiting, gi irritaion, respiratory depression, and dyspnea
How is rotenone toxicity best diagnosed?
blood analysis reveals incidence of hypoglycemia
What is the treatment given for rotenone toxicity?
diazepam-control seizures
dextrose- given IV
What is contraindicated with rotenone toxicity?
phenothiazine tranquilizers
What is the specific antidote given for rotenone toxicity?
there is no specific antidote available
What spp. is Amitraz used on?
cattle, dogs, adn pigs
What is the MOA of Amitraz
its an alpha-adrenergic agonist and MAO inhibitor
What organs are targeted with Amitraz?
CNS and cardiovascular system
What clinical signs can be seen with Amitraz intoxication?
vomiting, diarrhea, ataxia, seizures
What is Citrus Oil Extracts used for?
control of lice, ticks, and fleas
What system is most effected with Citrus Oil Extracts?
Nervous system
What clinical signs are seen with citrus oil extract toxicity?
ataxia, vasodilation, CNS depression
What is boric acid used for?
used to control ants and roaches
What spp. is most effected by toxicity of boric acid?
cats, and to a lesser extent dogs
Where is the site of greatest damage in boric acid toxicity?
in the kidney due to accumulation
What are some clinical signs that are observed with boric acid toxicity?
GI tract disturbances
Muscle weakness
CNS depression
Comprimised renal function
Metabolic acidosis
Occassional tremors and seizures
What are the characteristic lesions associated with boric acid toxicity?
gastroenteritis
nephrosis
cerebral edema
hepatic and renal fatty degeneration
What is the common name for N,N-diethyltoluamide?
Deet
What is the use of deet?
used as an insect repellant
What is the MOA of Deet?
it is neurotoxic
What are some clinical signs that are evident in people affected with deet toxicity?
confusion, acute manic psychosis, headaches, ataxia, tremors, encephalopathy, convulsions
What signs are seen with acute toxicity to deet?
seizures, hypotension, bradycardia, coma
What agent is present in mothproofing products?
napthalene
What are clincal signs seen with napthalene?
vomiting, hemoglobinuria, Heinz bodies
What is the source of molluscacides:metaldehyde?
pellets and baits for slugs and snails
What three things are decreased in the brain due to toxicity?
GABA, Norepinephrine, and Serotonin
What imbalances can be observed with metaldehyde toxicity?
high fever, and electrolyte and acid-base imbalance
What metabolic process is seen with metaldehyde toxicity?
metabolic acidosis
What is the most popular molluscacide which has no specific hazard?
copper sulfate
What molluscacide is receiving a growing amount of attention?
pentachlorophenol