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38 Cards in this Set
- Front
- Back
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What is Toxoplasmosis caused by
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Obligate intracellular protozoan of the Sporozoa group
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What animals pass Toxo
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Cats and other carnivores as the definitive host and other animals such as cattle pigs chicks
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Why do you get Toxo ie how is it transmitted
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eating undercooked meat or exposure to cat feces
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If a mother was previoulsy infected with Toxo will she pass it on.
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NO, her immunity would have killed the disease
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In most cases Toxo is what...
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subclinical
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What if toxo is not subclinical
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severe meningoencephalyomyelitis, with large inflammatory lesions, necrosis, calcification,cyst formation, and vascular changes in retina
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How do you diagnose Toxo
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Serum IgG v. IgM
Demo of protozoa in tissue secretions, smears, or body fluids |
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How do you prevent Toxo
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preg woment should not eat under cooked pork/ lamb/ beef
Stay away from cat feces Not to garden (more likely to get it from this) |
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Other disease
HBV |
DNA virus
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HCV
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RNA virus
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treponema pallidum
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syphillis
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Parvovirus B19-
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DNA virus
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Enterovirsus
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Picrornavirus
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VZV
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DNA herpes virus causing chicken pox
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Treponema pallidum more indepth
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Congenital syphillis
Can lead to serious fetal disease. Organ failure and death of featus. First subclinical and then rhinitus and maculopapular rash. Late bony destruction and CV syphilis are common in untreated infants who survive the initial course of disease |
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Human parvovirus B-19
whats the main sign |
Erythema infectiosum (slapped cheek syndrome)
Tiny naked SS DNA virus |
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What cells does parvo infect
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Erythoid precursor cells. Can lead to aplastic crisis. Permanent immunity after infection
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Primary infnx of parvo will cause
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Fetus may develop necrosis of hepatocytes, hemolysis, anemia, cardiac failure and hydrops fetalis, and death
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Varicella Zoster
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chance of infxn gets higher as trimester progresses.
Is not recognised by a constellation of abnormalities: low birth weight, hypoplasia of extremity, cicatrical skin scarring, localized muscular atrophy |
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Rubella (german measles)
caused by what type of virus |
non-arthropod borne toga virus. Small + strand RNA virus with envelope
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Rubella causes what in children and adults?
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Acute exanthematous disease, not very serious.
Over half of adult infxns are asymptomatic |
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Rubella unlike like varicella zoster....
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The infection get worse if it starts early in trimester
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Asymptomatic children show rebuella where....
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In their throat, urine, feces, and CSF
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The signs baby with Rubella is going to show
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slow growth, so small during gestational age with signs of early cataracts, cardiac malformations, deafness, microcephaly, spastic displegia, chorioretinitis and glaucoma
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What is the main sign of rubella
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a rubelliform rash. May appear normal at birth but develops encephalitis or interstitial pneumonitis
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If rubella not severe what can be overlooked
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deafness or psychomotor retardation
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CMV is caused by what type of virus
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Herpesvirus which is a large enveloped dsDNA virus
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How is CMV transmitted
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oral or genital
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CMV is known for its latency which is
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Primary CMV resolves into a latent subclinical infxn lasting for life. 50-80% of people are infected
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CMV causes
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mononucleosis and the people with children are the worst off
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CMV in utero causes
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microcephaly, intracerebral calcification, pyschomotor retardation
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CMV in utero causes the most common which is
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psychomotor retardation and sensorineural hearing loss
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Herpes simplex type 2 is what kind of virus
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DS DNA virus
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How is it Herpes transmitted
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direct contact with infected secretions. Usually a STD
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If you don't show lesion you can still pass HSV2 TF
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True
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How do infants get HSV
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through the birthcanal rarely retrograde
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What does HSV-2 cause in babies. Can HSV-1 cause the same thing. ANs. yest
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diffuse encephalitis, 60% die from overwhelming infxn and majority of survivors are left with severe ocular and neurological sequelae
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Prevent HSV from babies
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Caesarian birth
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