Topic 2 Toxic Chemicals And Toxic Effects

Front 1

Toxicity

Back 1

Some chemicals are much more toxic than others which means that the dose required to cause harm is much less.

Toxic effect of a substance is dependent on many factors including the nature of the chemical, route of exposure, site of action, metabolic pathway and the dose.

Front 2

RTECS

(Registry of Toxic Effects of Chemical Substances)

Back 2

(1) primary irritation; (2) mutagenic effects; (3) reproductive effects; (4) tumorigenic effects; (5) acute toxicity; and (6) other multiple dose toxicity.

Front 3

MSDS

Material Safety Data Sheets

Back 3

contain information on toxicity of the substance and other hazards including fire and explosion, corrosion and chemical reactivity.

Front 4

Clinical Toxicology Information Services

Back 4

These services provide information on the emergency treatment of poisoning, diagnosis, assays and antidotes.

Front 5

Local toxic effects

Back 5

Local toxic effects are those that occur at the site of first contact, such as corrosive burns on the skin

Front 6

Systemic toxic effects

Back 6

Systemic toxic effects are those that occur as a result of the absorption and distribution of the chemical from the point of entry, to a distant site at which the deleterious effect occurs.

central nervous system (CNS)

peripheral nervous system (PNS)

cardiovascular system (CVS)

blood and blood forming tissues

liver

kidneys